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Completed Phase 1Phase 2 Interventional Results available

Tipifarnib and Combination Chemotherapy in Treating Patients With Stage II or Stage III Breast Cancer

ClinicalTrials.gov ID: NCT00470301

Public ClinicalTrials.gov record NCT00470301. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 7, 2026, 12:11 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I-II Study of R115777 (Tipifarnib, Zarnestra®) Plus Sequential Weekly Paclitaxel Followed by Dose-Dense Doxorubicin and Cyclophosphamide in Patients With Stage IIB-IIIC Breast Cancer

Study identification

NCT ID
NCT00470301
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
60 participants

Conditions and interventions

Interventions

  • cyclophosphamide Drug
  • doxorubicin Drug
  • paclitaxel Drug
  • tipifarnib Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2007
Primary completion
Aug 31, 2013
Completion
Aug 31, 2013
Last update posted
Feb 15, 2021

2007 – 2013

United States locations

U.S. sites
7
U.S. states
3
U.S. cities
4
Facility City State ZIP Site status
H. Lee Moffitt Cancer Center and Research Institute Tampa Florida 33612
Mount Sinai Medical Center New York New York 10029
Columbia University Medical Center New York New York 10032
Weill Medical College of Cornell University New York New York 10065
Albert Einstein College of Medicine The Bronx New York 10461
Montefiore Medical Center The Bronx New York 10467-2490
M D Anderson Cancer Center Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00470301, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 15, 2021 · Synced May 7, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00470301 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →