A Safety and Efficacy Study Comparing Naltrexone SR/Bupropion SR and Placebo in Obese Subjects With Type 2 Diabetes
Public ClinicalTrials.gov record NCT00474630. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double Blind, Placebo Controlled Study Comparing the Safety and Efficacy of Naltrexone 32 mg Sustained Release (SR)/Bupropion 360 mg Sustained Release (SR) and Placebo in Obese Subjects With Type 2 Diabetes Mellitus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is determine whether the combination of naltrexone SR and bupropion SR is safe and effective in treating obesity in subjects with type 2 diabetes.
Study identification
- NCT ID
- NCT00474630
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 505 participants
Conditions and interventions
Conditions
Interventions
- Naltrexone SR 32 mg/bupropion SR 360 mg/ day Drug
- Placebo Drug
- Ancillary therapy Behavioral
Drug · Behavioral
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2007 (Type not available)
- Primary completion
- Jun 2009 (Actual)
- Completion
- Jun 2009 (Actual)
- Last update posted
- Nov 21, 2014
2007 – 2009
United States locations
- U.S. sites
- 53
- U.S. states
- 25
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| SelfCenter, PC | Fairhope | Alabama | 36532 | — |
| Pivotal Research Centers | Peoria | Arizona | 85381 | — |
| HOPE Research Institute | Phoenix | Arizona | 85050 | — |
| HealthStar Research | Hot Springs | Arkansas | 71913 | — |
| Impact Clinical Trials | Beverly Hills | California | 90211 | — |
| Northern California Research | Carmichael | California | 98608 | — |
| Sierra Medical Research | Fresno | California | 93710 | — |
| Advance Clinical Research Institute | Orange | California | 92869 | — |
| Affiliated Research Institute | San Diego | California | 92108 | — |
| VA San Diego Healthcare System | San Diego | California | 92161 | — |
| Apex Research Institue | Santa Ana | California | 92705 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| LCFP Inc. | Fort Myers | Florida | 33907 | — |
| Miami Research Associates | Miami | Florida | 33143 | — |
| Suncoast Clinical Research | Palm Harbor | Florida | 34684 | — |
| University Clinical Research | Pembroke Pines | Florida | 33024 | — |
| CSRA Partners in Health, Inc | Augusta | Georgia | 30909 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Deaconess Clinic | Evansville | Indiana | 47713 | — |
| Northwest Indiana Center for Clinical Research | Valparaiso | Indiana | 46383 | — |
| Central Kentucky Research Associates, Inc. | Lexington | Kentucky | 40509 | — |
| L-Marc | Louisville | Kentucky | 40213 | — |
| Trover Center for Clinical Studies | Madisonville | Kentucky | 42431 | — |
| Pennington Biomedical Research Center | Baton Rouge | Louisiana | 70808 | — |
| Medical Research Institute | Slidell | Louisiana | 70458 | — |
| Health Trends Research, LLC | Baltimore | Maryland | 21209 | — |
| FutureCare Studies | Springfield | Massachusetts | 01103 | — |
| Twin Cities Clinical Research | Brooklyn Center | Minnesota | 55430 | — |
| The Center for Pharmaceutical Research | Kansas City | Missouri | 64114 | — |
| Mercy Health Research | St Louis | Missouri | 63141 | — |
| Radiant Research, Inc. | St Louis | Missouri | 63141 | — |
| Center for Nutrition and Metabolic Diseases, Univ. of Nevada | Reno | Nevada | 89557 | — |
| Endocrinology & Diabetes Consultants | Dover | New Hampshire | 03820 | — |
| Lovelace Scientific Resources | Albuquerque | New Mexico | 87108 | — |
| Diabetes care and Information Center | Flushing | New York | 11365 | — |
| Central New York Clinical Research | Manlius | New York | 13104 | — |
| Rochester Clinical Research, Inc | Rochester | New York | 14609 | — |
| Metrolina Medical Research | Charlotte | North Carolina | 28209 | — |
| Rapid Medical Research, Inc. | Cleveland | Ohio | 44122 | — |
| Central Ohio Nutrition Center, Inc. | Columbus | Ohio | 43213 | — |
| Wells Institute for Health Awareness | Kettering | Ohio | 45429 | — |
| Your Diabetes Endocrine and Nutrition Group | Mentor | Ohio | 44060 | — |
| Mountain View Clinical Research | Greer | South Carolina | 29349 | — |
| Palmetto Medical Research | Mt. Pleasant | South Carolina | 29464 | — |
| ClinSearch | Chattanooga | Tennessee | 37404 | — |
| Clinical Research Associates, Inc. | Nashville | Tennessee | 37203 | — |
| The Cooper Institute | Dallas | Texas | 75230 | — |
| Baylor Endocrine Center | Dallas | Texas | 75246 | — |
| Diabetes Center of the Southwest | Midland | Texas | 79705 | — |
| InVisions Consultants, LLC | San Antonio | Texas | 78217 | — |
| Diabetes & Glandular Disease Research Associates, Inc. | San Antonio | Texas | 78229-4801 | — |
| Summit Research Network, Inc. | Seattle | Washington | 98104 | — |
| Northside Internal Medicine | Spokane | Washington | 99208 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00474630, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 21, 2014 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00474630 live on ClinicalTrials.gov.