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Terminated Phase 3 Interventional Results available

Pivotal Clinical Study of Endoscopic Ablation for Atrial Fibrillation (AF) in Patients That Have Failed Drugs

ClinicalTrials.gov ID: NCT00477230

Public ClinicalTrials.gov record NCT00477230. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 8, 2026, 10:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Pivotal Clinical Study of the CardioFocus Endoscopic Ablation System for the Treatment of Symptomatic Atrial Fibrillation (AF)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the study is to compare two types of treatment for atrial fibrillation (AF) that are designed to treat the symptoms of atrial fibrillation. The treatments being compared are: * A single catheter ablation procedure with the investigational EAS, a visually-guided, light-energy catheter * Standard drug therapy (antiarrhythmic drugs) To learn more about the CardioFocus ENABLE investigational clinical study, please contact the study site closest to you. Eligibility Criteria Persons with paroxysmal atrial fibrillation may be eligible for this study. Other study eligibility criteria include: * 18 to 80 years of age * Frequent episodes of AF * Failed at least 1 drug treatment for AF (beta-blockers or standard AADs) * Other criteria

Study identification

NCT ID
NCT00477230
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
CardioFocus
Industry
Enrollment
64 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2007
Primary completion
Apr 30, 2009
Completion
Apr 30, 2009
Last update posted
Jun 26, 2012

2007 – 2009

United States locations

U.S. sites
18
U.S. states
11
U.S. cities
18
Facility City State ZIP Site status
Arizona Arrhythmia Consultants Scottsdale Arizona 85260
Mercy General Hospital Sacramento California 95819-3633
University of California at San Francisco San Francisco California 94143
St. John's Health Center Santa Monica California
Palm Beach Heart Research Institute Atlantis Florida 33462
Florida Hospital Orlando Florida
Indiana University, Krannert Institute of Cardiology Indianapolis Indiana 46202
Genesis Medical Center Davenport Iowa
University of Michigan Ann Arbor Michigan 48109
William Beaumont Hospital Royal Oak Michigan
St. Luke's-Roosevelt New York New York
Strong Memorial Hosptial - University of Rochester Rochester New York 14627
Ohio State University Columbus Ohio 43210
University of Pennsylvania Hospital Philadelphia Pennsylvania 19096
Texas Cardiac Arrhythmia Research Austin Texas 78705
The Methodist Hospital Houston Texas 77030
University of Virginia Charlottesville Virginia
Sentara Cardiovascular Research Institute Norfolk Virginia 23507

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00477230, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 26, 2012 · Synced Sep 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00477230 live on ClinicalTrials.gov.

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