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Completed Phase 1 Interventional

A Phase 1 Study Investigating the Combination of RAD001, Cetuximab and Irinotecan as Second-line Therapy After FOLFOX (or XELOX) Plus Bevacizumab in Patients With Metastatic Colorectal Cancer

ClinicalTrials.gov ID: NCT00478634

Public ClinicalTrials.gov record NCT00478634. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 10, 2026, 9:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label, Multicenter Phase 1 Study Investigating the Combination of RAD001, Cetuximab and Irinotecan as Second-line Therapy After FOLFOX (or XELOX) Plus Bevacizumab (if Given as Part of Local Standard Practice) in Patient With Metastatic Colorectal Adenocarcinoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will assess the safety of RAD001 when given together with cetuximab and irinotecan

Study identification

NCT ID
NCT00478634
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
19 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2007
Primary completion
Aug 31, 2009
Completion
Aug 31, 2009
Last update posted
Nov 1, 2012

2007 – 2009

United States locations

U.S. sites
16
U.S. states
11
U.S. cities
16
Facility City State ZIP Site status
Highlands Oncology Group Fayetteville Arkansas 72701
Comprehensive nBlood and Cancer Care Bakersfield California 93309
UCSD - Moores Cancer Center La Jolla California 92037
Comprehensive Cancer Care Los Angeles California 90095
North Valley Hematology/Oncology Medical Group: The Thomas & Dorothy Leavey Cancer Center Northridge California 91325
Cancer Care Associates Medical Group, Inc. Redondo Beach California 90277
Norwalk Hospital Norwalk Connecticut 06850
Gerogetown University Lombardi Cancer Center Washington D.C. District of Columbia 20057
H. Lee Moffitt Cancer Center Tampa Florida 33612
Oncology Specialists Park Ridge Illinois 60068
Nevada Cancer Institute Las Vegas Nevada 89135
Roswell Park Cancer Institute Buffalo New York 14263
Richmond University Medical Center Staten Island New York 10310
UNC School of Medicine Chapel Hill North Carolina 27599
Oncology/Hematology Associates Bethlehem Pennsylvania 18017
Arlington Cancer Center Arlington Texas 76012

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00478634, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 1, 2012 · Synced Sep 10, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00478634 live on ClinicalTrials.gov.

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