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Completed Phase 1Phase 2 Interventional Results available

Hydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma Multiforme

ClinicalTrials.gov ID: NCT00486603

Public ClinicalTrials.gov record NCT00486603. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 13, 2026, 10:44 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I/II Trial of Hydroxychloroquine in Conjunction With Radiation Therapy and Concurrent and Adjuvant Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme

Study identification

NCT ID
NCT00486603
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Enrollment
92 participants

Conditions and interventions

Interventions

  • Radiation Radiation
  • hydroxychloroquine Drug
  • pharmacological study Other
  • temozolomide Drug

Radiation · Drug · Other

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 28, 2007
Primary completion
May 31, 2013
Completion
Dec 31, 2013
Last update posted
Jul 9, 2019

2007 – 2014

United States locations

U.S. sites
9
U.S. states
9
U.S. cities
9
Facility City State ZIP Site status
University of Alabama at Birmingham Comprehensive Cancer Center Birmingham Alabama 35294
H. Lee Moffitt Cancer Center and Research Institute at University of South Florida Tampa Florida 33612-9497
Winship Cancer Institute of Emory University Atlanta Georgia 30322
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore Maryland 21231-2410
Massachusetts General Hospital Boston Massachusetts 02114
Josephine Ford Cancer Center at Henry Ford Hospital Detroit Michigan 48202
Wake Forest University Comprehensive Cancer Center Winston-Salem North Carolina 27157-1096
Case Comprehensive Cancer Center Cleveland Ohio 44106-5065
Abramson Cancer Center of the University of Pennsylvania Philadelphia Pennsylvania 19104-4283

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00486603, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 9, 2019 · Synced May 13, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00486603 live on ClinicalTrials.gov.

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