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Terminated Phase 2 Interventional Results available

Study of Oral LBH589 in Adult Participants With Refractory/Resistant Cutaneous T-Cell Lymphoma (CTCL)

ClinicalTrials.gov ID: NCT00490776

Public ClinicalTrials.gov record NCT00490776. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 8:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Study of Oral LBH589 in Adult Patients With Cutaneous T-Cell Lymphoma Who Are Intolerant to or Have Progressed on or After Prior HDAC Inhibitor

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study evaluated the safety and efficacy of LBH589B in adult participants with refractory/resistant Cutaneous T-Cell Lymphoma and prior Histone Deacetylase (HDAC) inhibitor therapy.

Study identification

NCT ID
NCT00490776
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
9 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 5, 2007 (Actual)
Primary completion
Sep 2009 (Actual)
Completion
Sep 22, 2009 (Actual)
Last update posted
Aug 18, 2021

2007 – 2009

United States locations

U.S. sites
18
U.S. states
16
U.S. cities
18
Facility City State ZIP Site status
University of Alabama at Birmingham/ The Kirklin Clinic Birmingham Alabama 35233 —
UCLA Medical Center School of Medicine/ Dpt of Hematology-Oncology Los Angeles California 90095 —
University of Colorado Health Sciences Center/Anschutz Cancer Pavillion Aurora Colorado 80010 —
Florida Academic Dermatology Centers Miami Florida 33136 —
Medical College of Georgia Augusta Georgia 30912 —
Rush Presbyterian Hospital/St. Luke's Medical Center Chicago Illinois 60612 —
St. Louis University Cancer Cennter St Louis Missouri 63110 —
Nebraska Medical Center Omaha Nebraska 68198 —
Roswell Park Cancer Institute Buffalo New York 14263 —
NYU Clinical Cancer Center New York New York 10016 —
Our Lady of Mercy Medical Center/Comprehensive Cancer Center The Bronx New York 10466 —
Wake University Health Sciences Winston-Salem North Carolina 27157 —
University of Oklahoma-Tulsa Tulsa Oklahoma 74104 —
Craig Okada Portland Oregon 97239 —
University of Pittsburg Medical Center Pittsburgh Pennsylvania 15213 —
The Jones Clinic Germantown Tennessee 38138 —
MD Anderson Cancer Center/University of Texas Houston Texas 77030 —
Seattle Cancer Care Alliance Seattle Washington 98109-102 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00490776, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 18, 2021 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00490776 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →