1st or 2nd Line MBC (Metastatic Breast Cancer) With Previous Avastin (Bevacizumab) Therapy
Public ClinicalTrials.gov record NCT00493636. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Randomized Phase 2b Study of Sorafenib Compared to Placebo When Administered in Combination With Chemotherapy for Patients With Locally Advanced or MBC That Has Progressed During or After Bevacizumab Therapy
Study identification
- NCT ID
- NCT00493636
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Accelerated Community Oncology Research Network
- Other
- Enrollment
- 160 participants
Conditions and interventions
Conditions
Interventions
- Capecitabine Drug
- Gemcitabine Drug
- Placebo Drug
- Sorafenib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2007
- Primary completion
- Aug 31, 2010
- Completion
- Oct 31, 2012
- Last update posted
- May 19, 2014
2007 – 2012
United States locations
- U.S. sites
- 44
- U.S. states
- 23
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Providence Cancer Center / Katmai Oncology Group LLC | Anchorage | Alaska | 99508 | — |
| Highlands Oncology Group | Fayetteville | Arkansas | 72703 | — |
| Compassionate Cancer Care-Corona | Corona | California | 92879 | — |
| Compassionate Cancer Care-Fountain Valley | Fountain Valley | California | 92879 | — |
| California Cancer Care | Greenbrae | California | 94904-2007 | — |
| Long Beach Memorial Medical Center | Long Beach | California | 90806 | — |
| Compassionate Cancer Care-Riverside | Riverside | California | 92501 | — |
| Sutter Cancer Center | Sacramento | California | 98516 | — |
| California Pacific Medical Center | San Francisco | California | 94107 | — |
| University of California San Francisco Comprehensive Cancer Center | San Francisco | California | 94115 | — |
| Front Range Cancer Specialists | Fort Collins | Colorado | 80528 | — |
| Hematology Oncology PC / Bennett Cancer Center | Stamford | Connecticut | 06902 | — |
| Oncology Associates of Bridgeport | Trumbull | Connecticut | 06611 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Washington Cancer Institute | Washington D.C. | District of Columbia | 20010 | — |
| Pasco Hernando Oncology Associates PA | Brooksville | Florida | 34613 | — |
| Pasco Hernando Oncology Associates PA | New Port Richey | Florida | 34652 | — |
| Augusta Oncology Associates, PC | Augusta | Georgia | 30901 | — |
| Cascade Cancer Center | Macon | Georgia | 31201 | — |
| Central Georgia Cancer Care | Macon | Georgia | 31201 | — |
| Northwest Georgia Oncology Center | Marietta | Georgia | 30060 | — |
| Northwestern University-Robert H. Lurie Comprehensive Cancer Center | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Quincy Medical Group | Quincy | Illinois | 62301 | — |
| Northern Indiana Cancer Research Consortium | South Bend | Indiana | 46601 | — |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809 | — |
| Maine Center for Cancer Medicine | Scarborough | Maine | 04474-9308 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01107 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48105 | — |
| Columbia Comprehensive Cancer Care Clinic & Research Institute | Jefferson City | Missouri | 65109 | — |
| Oncology Hematology Specialists, PA | Denville | New Jersey | 07134 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Hematology Oncology Associates of New York | East Syracuse | New York | 13057 | — |
| Queens Cancer Center | Jamaica | New York | 11432 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | — |
| Presbyterian Hospital | Charlotte | North Carolina | 28204 | — |
| North Coast Cancer Care | Sandusky | Ohio | 44870 | — |
| Hematology Oncology of Northeast Pennsylvania | Dunmore | Pennsylvania | 18512 | — |
| Pennsylvania Oncology Hematology Associates | Philadelphia | Pennsylvania | 19106 | — |
| Charleston Hematology Oncology Associates | Charleston | South Carolina | 29403 | — |
| The West Clinic | Memphis | Tennessee | 38120 | — |
| Oncology Alliance | Glendale | Wisconsin | 53212 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00493636, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 19, 2014 · Synced May 16, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00493636 live on ClinicalTrials.gov.