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Completed Phase 2 Interventional Results available

Adj TC + Herceptin Early Stage Breast Cancer

ClinicalTrials.gov ID: NCT00493649

Public ClinicalTrials.gov record NCT00493649. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 23, 2026, 5:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Trial of Adjuvant TC (Docetaxel/Cyclophosphamide) Plus Trastuzumab in HER2-Positive Early Stage Breast Cancer Patients

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this research study is to find out what effects (good and bad) docetaxel/cyclophosphamide (brand names: Taxotere and Cytoxan, or TC) plus trastuzumab (brand name: Herceptin, or H) has HER2+ breast cancer.

Study identification

NCT ID
NCT00493649
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
US Oncology Research
Industry
Enrollment
493 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2007
Primary completion
Mar 31, 2013
Completion
Mar 31, 2013
Last update posted
Nov 2, 2016

2007 – 2013

United States locations

U.S. sites
69
U.S. states
23
U.S. cities
65
Facility City State ZIP Site status
Birmingham Hematology and Oncology Birmingham Alabama 35205
Hematology Oncology Associates Phoenix Arizona 85012
Northern AZ Hematology & Oncology Associates Sedona Arizona 86336
Arizona Oncology Associates DBA HOPE Tucson Arizona 85704
Rocky Mountain Cancer Center-Rose Denver Colorado 80220
Connecticut Oncology & Hematology, LLP Torrington Connecticut 06790
Florida Cancer Institute New Port Richey Florida 34655
Ocala Oncology Center Ocala Florida 34474
Cancer Centers of Florida, P.A. Ocoee Florida 34761
Hematology Oncology Associates of IL Chicago Illinois 60611
Cancer Care & Hematology Specialists of Chicagoland Niles Illinois 60714
Central Indiana Cancer Centers Indianapolis Indiana 46227
Hope Center Terre Haute Indiana 47802
Kansas City Cancer Centers-Southwest Overland Park Kansas 66210
Maryland Oncology Hematology, P.A. Columbia Maryland 21044
Alliance Hematology Oncology P.A. Westminster Maryland 21157
Minnesota Oncology Hematology, P.A. Minneapolis Minnesota 55404
Missouri Cancer Associates Columbia Missouri 65201
Arch Medical Services, Inc. St Louis Missouri 63141
Comprehensive Cancer Centers of Nevada Henderson Nevada 89052
Hematology-Oncology Associates of NNJ, P.A. Morristown New Jersey 07960
New Mexico Cancer Care Associates Santa Fe New Mexico 87505
New York Oncology Hematology, P.C. Albany New York 12006
Ruth Oratz MD New York New York 10016
Interlakes Oncology Hematology, PC Rochester New York 14623
Cancer Centers of North Carolina Raleigh North Carolina 27607
Greater Dayton Cancer Center Kettering Ohio 45409
Willamette Valley Cancer Center Eugene Oregon 97401
Medical Oncology Associates Kingston Pennsylvania 18704
Cancer Centers of the Carolinas Greenville South Carolina 29605
Texas Cancer Center-Abilene (South) Abilene Texas 79606
Texas Oncology, P.A.-Amarillo Amarillo Texas 79106
Texas Cancer Center Arlington Texas 76014
Texas Oncology Cancer Center Austin Texas 78731
Mamie McFaddin Ward Cancer Center Beaumont Texas 77702
Texas Oncology, P.A.-Bedford Bedford Texas 76022
Texas Cancer Center at Medical City Dallas Texas 75230
Texas Oncology, P.A. Dallas Texas 75231
Methodist Charlton Cancer Ctr. Dallas Texas 75237
Texas Oncology, P.A. Dallas Texas 75246
Texas Cancer Center Denton Texas 76210
El Paso Cancer Treatment Ctr El Paso Texas 79915
Texas Oncology, P.A. Fort Worth Texas 76104
Texas Oncology, P.A. Garland Texas 75042
Texas Oncology, P.A. Houston Texas 77024
Lake Vista Cancer Center Lewisville Texas 75067
Longview Cancer Center Longview Texas 75601
South Texas Cancer Center-McAllen McAllen Texas 78503
Texas Cancer Center of Mesquite Mesquite Texas 75150
Allison Cancer Center Midland Texas 79701
Texas Oncology-Odessa Odessa Texas 79761
Paris Regional Cancer Center Paris Texas 75460
San Antonio Tumor and Blood Clinic San Antonio Texas 78217
HOAST-Medical Dr. San Antonio Texas 78229
Texas Cancer Center-Sherman Sherman Texas 75090
Texas Oncology Cancer Center-Sugar Land Sugar Land Texas 77479
Tyler Cancer Center Tyler Texas 75702
Texas Oncology Cancer Care and Research Waco Texas 76712
Texas Oncology PA Webster Texas 77598
Texoma Cancer Center Wichita Falls Texas 76310
Fairfax Northern VA Hem-Onc PC Fairfax Virginia 22031
Virginia Oncology Associates Norfolk Virginia 23502
Onc and Hem Associates of SW VA, Inc. Salem Virginia 24153
Highline Medical Oncology Burien Washington 98166
Puget Sound Cancer Center-Edmonds Edmonds Washington 98026
Puget Sound Cancer Center-Seattle Seattle Washington 98133
Cancer Care Northwest-South Spokane Washington 99202
Northwest Cancer Specialists-Vancouver Vancouver Washington 98684
Yakima Valley Mem Hosp/North Star Lodge Yakima Washington 98902

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00493649, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 2, 2016 · Synced Sep 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00493649 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →