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Completed Phase 2 Interventional Results available

Adj TC + Herceptin Early Stage Breast Cancer

ClinicalTrials.gov ID: NCT00493649

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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT00493649. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 11, 2026, 10:11 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Trial of Adjuvant TC (Docetaxel/Cyclophosphamide) Plus Trastuzumab in HER2-Positive Early Stage Breast Cancer Patients

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this research study is to find out what effects (good and bad) docetaxel/cyclophosphamide (brand names: Taxotere and Cytoxan, or TC) plus trastuzumab (brand name: Herceptin, or H) has HER2+ breast cancer.

Study identification

NCT ID
NCT00493649
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
US Oncology Research
Industry
Enrollment
493 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2007 (Type not available)
Primary completion
Apr 2013 (Actual)
Completion
Apr 2013 (Actual)
Last update posted
Nov 3, 2016

2007 – 2013

United States locations

U.S. sites
69
U.S. states
23
U.S. cities
65
Facility City State ZIP Site status
Birmingham Hematology and Oncology Birmingham Alabama 35205 —
Hematology Oncology Associates Phoenix Arizona 85012 —
Northern AZ Hematology & Oncology Associates Sedona Arizona 86336 —
Arizona Oncology Associates DBA HOPE Tucson Arizona 85704 —
Rocky Mountain Cancer Center-Rose Denver Colorado 80220 —
Connecticut Oncology & Hematology, LLP Torrington Connecticut 06790 —
Florida Cancer Institute New Port Richey Florida 34655 —
Ocala Oncology Center Ocala Florida 34474 —
Cancer Centers of Florida, P.A. Ocoee Florida 34761 —
Hematology Oncology Associates of IL Chicago Illinois 60611 —
Cancer Care & Hematology Specialists of Chicagoland Niles Illinois 60714 —
Central Indiana Cancer Centers Indianapolis Indiana 46227 —
Hope Center Terre Haute Indiana 47802 —
Kansas City Cancer Centers-Southwest Overland Park Kansas 66210 —
Maryland Oncology Hematology, P.A. Columbia Maryland 21044 —
Alliance Hematology Oncology P.A. Westminster Maryland 21157 —
Minnesota Oncology Hematology, P.A. Minneapolis Minnesota 55404 —
Missouri Cancer Associates Columbia Missouri 65201 —
Arch Medical Services, Inc. St Louis Missouri 63141 —
Comprehensive Cancer Centers of Nevada Henderson Nevada 89052 —
Hematology-Oncology Associates of NNJ, P.A. Morristown New Jersey 07960 —
New Mexico Cancer Care Associates Santa Fe New Mexico 87505 —
New York Oncology Hematology, P.C. Albany New York 12006 —
Ruth Oratz MD New York New York 10016 —
Interlakes Oncology Hematology, PC Rochester New York 14623 —
Cancer Centers of North Carolina Raleigh North Carolina 27607 —
Greater Dayton Cancer Center Kettering Ohio 45409 —
Willamette Valley Cancer Center Eugene Oregon 97401 —
Medical Oncology Associates Kingston Pennsylvania 18704 —
Cancer Centers of the Carolinas Greenville South Carolina 29605 —
Texas Cancer Center-Abilene (South) Abilene Texas 79606 —
Texas Oncology, P.A.-Amarillo Amarillo Texas 79106 —
Texas Cancer Center Arlington Texas 76014 —
Texas Oncology Cancer Center Austin Texas 78731 —
Mamie McFaddin Ward Cancer Center Beaumont Texas 77702 —
Texas Oncology, P.A.-Bedford Bedford Texas 76022 —
Texas Cancer Center at Medical City Dallas Texas 75230 —
Texas Oncology, P.A. Dallas Texas 75231 —
Methodist Charlton Cancer Ctr. Dallas Texas 75237 —
Texas Oncology, P.A. Dallas Texas 75246 —
Texas Cancer Center Denton Texas 76210 —
El Paso Cancer Treatment Ctr El Paso Texas 79915 —
Texas Oncology, P.A. Fort Worth Texas 76104 —
Texas Oncology, P.A. Garland Texas 75042 —
Texas Oncology, P.A. Houston Texas 77024 —
Lake Vista Cancer Center Lewisville Texas 75067 —
Longview Cancer Center Longview Texas 75601 —
South Texas Cancer Center-McAllen McAllen Texas 78503 —
Texas Cancer Center of Mesquite Mesquite Texas 75150 —
Allison Cancer Center Midland Texas 79701 —
Texas Oncology-Odessa Odessa Texas 79761 —
Paris Regional Cancer Center Paris Texas 75460 —
San Antonio Tumor and Blood Clinic San Antonio Texas 78217 —
HOAST-Medical Dr. San Antonio Texas 78229 —
Texas Cancer Center-Sherman Sherman Texas 75090 —
Texas Oncology Cancer Center-Sugar Land Sugar Land Texas 77479 —
Tyler Cancer Center Tyler Texas 75702 —
Texas Oncology Cancer Care and Research Waco Texas 76712 —
Texas Oncology PA Webster Texas 77598 —
Texoma Cancer Center Wichita Falls Texas 76310 —
Fairfax Northern VA Hem-Onc PC Fairfax Virginia 22031 —
Virginia Oncology Associates Norfolk Virginia 23502 —
Onc and Hem Associates of SW VA, Inc. Salem Virginia 24153 —
Highline Medical Oncology Burien Washington 98166 —
Puget Sound Cancer Center-Edmonds Edmonds Washington 98026 —
Puget Sound Cancer Center-Seattle Seattle Washington 98133 —
Cancer Care Northwest-South Spokane Washington 99202 —
Northwest Cancer Specialists-Vancouver Vancouver Washington 98684 —
Yakima Valley Mem Hosp/North Star Lodge Yakima Washington 98902 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00493649, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 3, 2016 · Synced Nov 11, 2026

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