Efficacy and Safety of Clevudine Compared With Adefovir in Patients With HBeAg Positive Chronic Hepatitis Due to Hepatitis B Virus
Public ClinicalTrials.gov record NCT00496002. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Randomized, Double-Blind, Active-Control, 96 Week, Phase III Trial of the Efficacy and Safety of Clevudine Compared With Adefovir at Weeks 48 and 96 in Nucleoside Treatment-Naïve Patients With HBeAg Positive Chronic Hepatitis Due to Hepatitis B Virus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objectives of this study are to compare in nucleoside treatment-naïve subjects, the efficacy and safety of clevudine 30 mg once daily versus adefovir 10 mg once daily, each as monotherapy, for 48 weeks and 96 weeks.
Study identification
- NCT ID
- NCT00496002
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 16 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2007 (Type not available)
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Apr 27, 2009
Started 2007
United States locations
- U.S. sites
- 66
- U.S. states
- 22
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham | Birmingham | Alabama | — | — |
| Not listed | Anaheim | California | 92801 | — |
| Advanced Clinical Research Institution | Anaheim | California | — | — |
| Not listed | Fresno | California | 93710 | — |
| Not listed | Fresno | California | — | — |
| Not listed | Los Angeles | California | 90045 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | — | — |
| West Gastroenterology Medical Group | Los Angeles | California | — | — |
| Not listed | Los Angeles | California | — | — |
| Not listed | San Clemente | California | — | — |
| Not listed | San Diego | California | 92123 | — |
| Medical Associates Research Group | San Diego | California | — | — |
| Sharp Rees-Stealy Medical Group Inc | San Diego | California | — | — |
| Not listed | San Diego | California | — | — |
| Quest Clinical Research | San Francisco | California | 94115 | — |
| California Pacific Medical Center | San Francisco | California | — | — |
| Ucsf/Sfgh | San Francisco | California | — | — |
| San Mateo Medical Center | San Mateo | California | — | — |
| Not listed | Norwich | Connecticut | 06360 | — |
| The William W. Backus Hospital | Norwich | Connecticut | — | — |
| Not listed | Tampa | Florida | 33614 | — |
| Infectious Disease Research Institute, Inc. | Tampa | Florida | — | — |
| Not listed | Tampa | Florida | — | — |
| Liver Center | Honolulu | Hawaii | — | — |
| Memphis Gastroenterology Group | Germantown | Indiana | — | — |
| Iowa Health-Des Moines | Des Moines | Iowa | — | — |
| Tulane Medical Center | New Orleans | Louisiana | — | — |
| Not listed | New Orleans | Louisiana | — | — |
| Banks Hepatology Institute | College Park | Maryland | — | — |
| Not listed | Boston | Massachusetts | — | — |
| Digestive Health Specialists | Tupelo | Mississippi | — | — |
| Saint Louis University | St Louis | Missouri | — | — |
| Not listed | Hillsborough | New Jersey | 08844 | — |
| UMA Research Department | Binghamton | New York | — | — |
| Not listed | Manhasset | New York | — | — |
| Beth Israel Medical Center | New York | New York | — | — |
| VAMC/NYU | New York | New York | — | — |
| Weill Cornell Medical College | New York | New York | — | — |
| Not listed | New York | New York | — | — |
| Not listed | Asheville | North Carolina | 28801 | — |
| Asheville Gastroenterology | Asheville | North Carolina | — | — |
| Duke University | Durham | North Carolina | — | — |
| Not listed | Cincinnati | Ohio | 45242 | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Portland | Oregon | 97220 | — |
| Not listed | Portland | Oregon | 97239 | — |
| Oregon Heath and Science University (OHSU) | Portland | Oregon | — | — |
| The Oregon Clinica P.C. | Portland | Oregon | — | — |
| Nashville Gastrointestinal Specialists, Inc | Nashville | Tennessee | — | — |
| Not listed | Austin | Texas | 78745 | — |
| Austin Gastroenterology, PA | Austin | Texas | — | — |
| Baylor University Medical Center | Dallas | Texas | — | — |
| Methodist Transplant Physicians | Dallas | Texas | — | — |
| Not listed | Galveston | Texas | — | — |
| Not listed | Houston | Texas | 77028 | — |
| Advanced Liver Therapies | Houston | Texas | — | — |
| Century Clinical Research, Inc. | Houston | Texas | — | — |
| Brooke Army Medical Center | San Antonio | Texas | — | — |
| Not listed | Salt Lake City | Utah | 84121 | — |
| Not listed | Salt Lake City | Utah | — | — |
| University of Virginia | Charlottesville | Virginia | — | — |
| Not listed | Fairfax | Virginia | 22031 | — |
| Metropolitan Research | Fairfax | Virginia | — | — |
| Not listed | Richmond | Virginia | — | — |
| Virginia Mason Medical Center | Seattle | Washington | — | — |
| Not listed | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 68 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00496002, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2009 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00496002 live on ClinicalTrials.gov.