ClinicalTrials.gov record
Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy
ClinicalTrials.gov ID: NCT00499369
Public ClinicalTrials.gov record NCT00499369. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III Trial of Irinotecan-Based Chemotherapy Plus Cetuximab (NSC-714692) or Bevacizumab (NSC-704865) as Second-Line Therapy for Patients With Metastatic Colorectal Cancer Who Have Progressed on Bevacizumab With Either FOLFOX, OPTIMOX or XELOX
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized phase III trial is studying giving irinotecan and cetuximab together with bevacizumab to see how well it works compared with giving irinotecan and cetuximab alone in treating patients with metastatic colorectal cancer that progressed during first-line therapy. Drugs used in chemotherapy, such as irinotecan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as cetuximab and bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. It is not yet known whether irinotecan and cetuximab are more effective with or without bevacizumab in treating metastatic colorectal cancer.
Study identification
- NCT ID
- NCT00499369
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 72 participants
Conditions and interventions
Conditions
Interventions
- irinotecan hydrochloride Drug
- leucovorin calcium Drug
- fluorouracil Drug
- cetuximab Biological
- bevacizumab Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2007 (Type not available)
- Primary completion
- Nov 2012 (Actual)
- Completion
- Nov 2012 (Actual)
- Last update posted
- Jul 31, 2014
2007 – 2012
United States locations
- U.S. sites
- 382
- U.S. states
- 39
- U.S. cities
- 262
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Saint Edward Mercy Medical Center | Fort Smith | Arkansas | 72903 | — |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | 91505 | — |
| East Bay Radiation Oncology Center | Castro Valley | California | 94546 | — |
| Eden Hospital Medical Center | Castro Valley | California | 94546 | — |
| Valley Medical Oncology Consultants-Castro Valley | Castro Valley | California | 94546 | — |
| City of Hope Medical Center | Duarte | California | 91010 | — |
| Northbay Cancer Center | Fairfield | California | 94533 | — |
| Valley Medical Oncology Consultants-Fremont | Fremont | California | 94538 | — |
| Glendale Memorial Hospital and Health Center | Glendale | California | 91204 | — |
| Marin General Hospital | Greenbrae | California | 94904 | — |
| Saint Rose Hospital | Hayward | California | 94545 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Fremont - Rideout Cancer Center | Marysville | California | 95901 | — |
| Highland General Hospital | Oakland | California | 94602 | — |
| Alta Bates Summit Medical Center - Summit Campus | Oakland | California | 94609 | — |
| Bay Area Breast Surgeons Inc | Oakland | California | 94609 | — |
| Bay Area Tumor Institute CCOP | Oakland | California | 94609 | — |
| Larry G Strieff MD Medical Corporation | Oakland | California | 94609 | — |
| Tom K Lee Inc | Oakland | California | 94609 | — |
| Palchak David MD | Pismo Beach | California | 93449 | — |
| Valley Care Health System - Pleasanton | Pleasanton | California | 94588 | — |
| Valley Medical Oncology Consultants | Pleasanton | California | 94588 | — |
| Sutter Roseville Medical Center | Roseville | California | 95661 | — |
| UC Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Doctors Medical Center- JC Robinson Regional Cancer Center | San Pablo | California | 94806 | — |
| Tahoe Forest Cancer Center | Truckee | California | 96161 | — |
| The Medical Center of Aurora | Aurora | Colorado | 80012 | — |
| Boulder Community Hospital | Boulder | Colorado | 80301 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| Memorial Hospital Colorado Springs | Colorado Springs | Colorado | 80909 | — |
| Porter Adventist Hospital | Denver | Colorado | 80210 | — |
| Exempla Saint Joseph Hospital | Denver | Colorado | 80218 | — |
| Presbyterian - Saint Lukes Medical Center - Health One | Denver | Colorado | 80218 | — |
| Rose Medical Center | Denver | Colorado | 80220 | — |
| Colorado Cancer Research Program CCOP | Denver | Colorado | 80224-2522 | — |
| Swedish Medical Center | Englewood | Colorado | 80113 | — |
| Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado | 81502 | — |
| North Colorado Medical Center | Greeley | Colorado | 80631 | — |
| Saint Anthony Hospital | Lakewood | Colorado | 80228 | — |
| Sky Ridge Medical Center | Lone Tree | Colorado | 80124 | — |
| Longmont United Hospital | Longmont | Colorado | 80501 | — |
| McKee Medical Center | Loveland | Colorado | 80539 | — |
| Saint Mary Corwin Medical Center | Pueblo | Colorado | 81004 | — |
| North Suburban Medical Center | Thornton | Colorado | 80229 | — |
| Exempla Lutheran Medical Center | Wheat Ridge | Colorado | 80033 | — |
| The Hospital of Central Connecticut | New Britain | Connecticut | 06050 | — |
| Bayhealth Medical Center at Kent General | Dover | Delaware | 19901 | — |
| Lombardi Comprehensive Cancer Center at Georgetown University | Washington D.C. | District of Columbia | 20057 | — |
| Edna Williams Cancer Center at the Baptist Cancer Institute | Jacksonville | Florida | 32207 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224-9980 | — |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | 33136 | — |
| Space Coast Cancer Centers-Titusville | Titusville | Florida | 32796 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Atlanta Regional CCOP | Atlanta | Georgia | 30342 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| Saint Joseph's Hospital of Atlanta | Atlanta | Georgia | 30342 | — |
| Well Star Cobb Hospital | Austell | Georgia | 30106 | — |
| John B Amos Cancer Center | Columbus | Georgia | 31904 | — |
| Atlanta VA Medical Center | Decatur | Georgia | 30033 | — |
| Dekalb Medical Center | Decatur | Georgia | 30033 | — |
| Gwinnett Medical Center | Lawrenceville | Georgia | 30045 | — |
| Wellstar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| Southern Regional Medical Center | Riverdale | Georgia | 30274 | — |
| Harbin Clinic Medical Oncology and Clinical Research | Rome | Georgia | 30165 | — |
| South Georgia Medical Center | Valdosta | Georgia | 31603 | — |
| Rush - Copley Medical Center | Aurora | Illinois | 60504 | — |
| Saint Joseph Medical Center | Bloomington | Illinois | 61701 | — |
| Graham Hospital Association | Canton | Illinois | 61520 | — |
| Memorial Hospital | Carthage | Illinois | 62321 | — |
| John H Stroger Jr Hospital of Cook County | Chicago | Illinois | 60612-3785 | — |
| Resurrection Healthcare | Chicago | Illinois | 60631 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Saint Anthony Memorial Hospital | Effingham | Illinois | 62401 | — |
| Eureka Hospital | Eureka | Illinois | 61530 | — |
| Galesburg Cottage Hospital | Galesburg | Illinois | 61401 | — |
| Illinois CancerCare Galesburg | Galesburg | Illinois | 61401 | — |
| Mason District Hospital | Havana | Illinois | 62644 | — |
| Hopedale Medical Complex - Hospital | Hopedale | Illinois | 61747 | — |
| Joliet Oncology-Hematology Associates Limited | Joliet | Illinois | 60435 | — |
| Adventist La Grange Memorial Hospital | La Grange | Illinois | 60525 | — |
| Mcdonough District Hospital | Macomb | Illinois | 61455 | — |
| Bromenn Regional Medical Center | Normal | Illinois | 61761 | — |
| Community Cancer Center Foundation | Normal | Illinois | 61761 | — |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | — |
| Ottawa Regional Hospital and Healthcare Center | Ottawa | Illinois | 61350 | — |
| Pekin Cancer Treatment Center | Pekin | Illinois | 61554 | — |
| Pekin Hospital | Pekin | Illinois | 61554 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61603 | — |
| Proctor Hospital | Peoria | Illinois | 61614 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| Illinois Oncology Research Association CCOP | Peoria | Illinois | 61615 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Illinois Valley Hospital | Peru | Illinois | 61354 | — |
| Perry Memorial Hospital | Princeton | Illinois | 61356 | — |
| Saint Margaret's Hospital | Spring Valley | Illinois | 61362 | — |
| Memorial Medical Center | Springfield | Illinois | 62781-0001 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Carle Clinic-Urbana Main | Urbana | Illinois | 61801 | — |
| Elkhart Clinic | Elkhart | Indiana | 46514-2098 | — |
| Michiana Hematology Oncology PC-Elkhart | Elkhart | Indiana | 46514 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Fort Wayne Medical Oncology and Hematology Inc-Parkview | Fort Wayne | Indiana | 46845 | — |
| Community Howard Regional Health | Kokomo | Indiana | 46904 | — |
| Indiana University Health La Porte Hospital | La Porte | Indiana | 46350 | — |
| Franciscan Saint Anthony Health-Michigan City | Michigan City | Indiana | 46360 | — |
| Michiana Hematology Oncology PC-Mishawaka | Mishawaka | Indiana | 46545-1470 | — |
| Saint Joseph Regional Medical Center-Mishawaka | Mishawaka | Indiana | 46545-1470 | — |
| Michiana Hematology Oncology PC-Plymouth | Plymouth | Indiana | 46563 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Michiana Hematology Oncology PC-South Bend | South Bend | Indiana | 46601 | — |
| South Bend Clinic | South Bend | Indiana | 46617 | — |
| Northern Indiana Cancer Research Consortium | South Bend | Indiana | 46628 | — |
| Michiana Hematology Oncology-PC Westville | Westville | Indiana | 46391 | — |
| McFarland Clinic PC-William R Bliss Cancer Center | Ames | Iowa | 50010 | — |
| Hematology Oncology Associates-Quad Cities | Bettendorf | Iowa | 52722 | — |
| Cedar Rapids Oncology Association | Cedar Rapids | Iowa | 52403 | — |
| Mercy Hospital | Cedar Rapids | Iowa | 52403 | — |
| Oncology Associates at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | — |
| Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | 50325 | — |
| Mercy Capitol | Des Moines | Iowa | 50307 | — |
| Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Iowa Oncology Research Association CCOP | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa | 50314 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| Iowa Lutheran Hospital | Des Moines | Iowa | 50316 | — |
| Siouxland Hematology Oncology Associates | Sioux City | Iowa | 51101 | — |
| Mercy Medical Center-Sioux City | Sioux City | Iowa | 51104 | — |
| Saint Luke's Regional Medical Center | Sioux City | Iowa | 51104 | — |
| Covenant Medical Center | Waterloo | Iowa | 50702 | — |
| Cancer Center of Kansas - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas - Dodge City | Dodge City | Kansas | 67801 | — |
| Cancer Center of Kansas - El Dorado | El Dorado | Kansas | 67042 | — |
| Cancer Center of Kansas - Fort Scott | Fort Scott | Kansas | 66701 | — |
| Hays Medical Center | Hays | Kansas | 67601 | — |
| Promise Regional Medical Center-Hutchinson | Hutchinson | Kansas | 65702 | — |
| Cancer Center of Kansas-Independence | Independence | Kansas | 67301 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Cancer Center of Kansas-Kingman | Kingman | Kansas | 67068 | — |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | — |
| Cancer Center of Kansas-Liberal | Liberal | Kansas | 67901 | — |
| Cancer Center of Kansas - Newton | Newton | Kansas | 67114 | — |
| Olathe Cancer Center | Olathe | Kansas | 66061 | — |
| Cancer Center of Kansas - Parsons | Parsons | Kansas | 67357 | — |
| Via Christi Hospital-Pittsburg | Pittsburg | Kansas | 66762 | — |
| Cancer Center of Kansas - Pratt | Pratt | Kansas | 67124 | — |
| Cancer Center of Kansas - Salina | Salina | Kansas | 67401 | — |
| Salina Regional Health Center | Salina | Kansas | 67401 | — |
| Stormont-Vail Regional Health Center | Topeka | Kansas | 66604 | — |
| Saint Francis Hospital and Medical Center - Topeka | Topeka | Kansas | 66606 | — |
| Cancer Center of Kansas - Wellington | Wellington | Kansas | 67152 | — |
| Associates In Womens Health | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas-Wichita Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas - Main Office | Wichita | Kansas | 67214 | — |
| Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Wichita CCOP | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas - Winfield | Winfield | Kansas | 67156 | — |
| Doctors Carrol, Sheth, Raghavan | Louisville | Kentucky | 40215 | — |
| Baton Rouge General Medical Center | Baton Rouge | Louisiana | 70806 | — |
| Harold Alfond Center for Cancer Care | Augusta | Maine | 04330 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Memorial Hospital at Easton - Shore Regional Cancer Center | Easton | Maryland | 21601 | — |
| Frederick Memorial Hospital | Frederick | Maryland | 21701 | — |
| Sturdy Memorial Hospital | Attleboro | Massachusetts | 02703 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Bixby Medical Center | Adrian | Michigan | 49221 | — |
| Hickman Cancer Center | Adrian | Michigan | 49221 | — |
| Saint Joseph Mercy Hospital | Ann Arbor | Michigan | 48106-0995 | — |
| Michigan Cancer Research Consortium Community Clinical Oncology Program | Ann Arbor | Michigan | 48106 | — |
| Oakwood Hospital | Dearborn | Michigan | 48124 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Saint John Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Green Bay Oncology - Escanaba | Escanaba | Michigan | 49431 | — |
| Hurley Medical Center | Flint | Michigan | 48502 | — |
| Genesys Regional Medical Center-West Flint Campus | Flint | Michigan | 48532 | — |
| Grand Rapids Clinical Oncology Program | Grand Rapids | Michigan | 49503 | — |
| Holland Community Hospital | Holland | Michigan | 49423 | — |
| Green Bay Oncology - Iron Mountain | Iron Mountain | Michigan | 49801 | — |
| Allegiance Health | Jackson | Michigan | 49201 | — |
| Sparrow Hospital | Lansing | Michigan | 48912 | — |
| Saint Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| Community Cancer Center of Monroe | Monroe | Michigan | 48162 | — |
| Mercy Memorial Hospital | Monroe | Michigan | 48162 | — |
| Mercy Health Partners-Hackley Campus | Muskegon | Michigan | 49442 | — |
| Michiana Hematology Oncology PC-Niles | Niles | Michigan | 49120 | — |
| Saint Joseph Mercy Oakland | Pontiac | Michigan | 48341-2985 | — |
| Saint Joseph Mercy Port Huron | Port Huron | Michigan | 48060 | — |
| William Beaumont Hospital-Royal Oak | Royal Oak | Michigan | 48073 | — |
| Saint Mary's of Michigan | Saginaw | Michigan | 48601 | — |
| Lakeland Hospital | Saint Joseph | Michigan | 49085 | — |
| Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | — |
| Saint John Macomb-Oakland Hospital | Warren | Michigan | 48093 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Essentia Health Duluth Clinic CCOP | Duluth | Minnesota | 55805 | — |
| Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | 55805 | — |
| Miller-Dwan Hospital | Duluth | Minnesota | 55805 | — |
| Fairview-Southdale Hospital | Edina | Minnesota | 55435 | — |
| Etzell, Paul S MD (UIA Investigator) | Fergus Falls | Minnesota | 56537 | — |
| Swenson, Wade II, MD (UIA Investigator) | Fergus Falls | Minnesota | 56537 | — |
| Unity Hospital | Fridley | Minnesota | 55432 | — |
| Hutchinson Area Health Care | Hutchinson | Minnesota | 55350 | — |
| Meeker County Memorial Hospital | Litchfield | Minnesota | 55355 | — |
| Mayo Clinic Health Systems-Mankato | Mankato | Minnesota | 56001 | — |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | — |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Virginia Piper Cancer Institute | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Metro-Minnesota CCOP | Saint Louis Park | Minnesota | 55416 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Saint Joseph's Hospital - Healtheast | Saint Paul | Minnesota | 55102 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | — |
| Minnesota Oncology and Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | — |
| Woodwinds Health Campus | Woodbury | Minnesota | 55125 | — |
| Singing River Hospital | Pascagoula | Mississippi | 39581 | — |
| Southeast Missouri Hospital | Cape Girardeau | Missouri | 63701 | — |
| Veterans Administration | Columbia | Missouri | 65201 | — |
| University of Missouri - Ellis Fischel | Columbia | Missouri | 65212 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| Saint Louis University Hospital | St Louis | Missouri | 63110 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Center for Cancer Care and Research | St Louis | Missouri | 63141 | — |
| Montana Cancer Consortium CCOP | Billings | Montana | 59101 | — |
| Northern Rockies Radiation Oncology Center | Billings | Montana | 59101 | — |
| Saint Vincent Healthcare | Billings | Montana | 59101 | — |
| Hematology-Oncology Centers of the Northern Rockies PC | Billings | Montana | 59102 | — |
| Billings Clinic | Billings | Montana | 59107-7000 | — |
| Bozeman Deaconess Cancer Center | Bozeman | Montana | 59715 | — |
| Bozeman Deaconess Hospital | Bozeman | Montana | 59715 | — |
| Saint James Community Hospital and Cancer Treatment Center | Butte | Montana | 59701 | — |
| Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Berdeaux, Donald MD (UIA Investigator) | Great Falls | Montana | 59405 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Northern Montana Hospital | Havre | Montana | 59501 | — |
| Saint Peter's Community Hospital | Helena | Montana | 59601 | — |
| Glacier Oncology PLLC | Kalispell | Montana | 59901 | — |
| Kalispell Medical Oncology | Kalispell | Montana | 59901 | — |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | — |
| Community Medical Hospital | Missoula | Montana | 59801 | — |
| Montana Cancer Specialists | Missoula | Montana | 59802 | — |
| Saint Patrick Hospital - Community Hospital | Missoula | Montana | 59802 | — |
| Guardian Oncology and Center for Wellness | Missoula | Montana | 59804 | — |
| Good Samaritan Hospital | Kearney | Nebraska | 68847 | — |
| Nebraska Cancer Research Center | Lincoln | Nebraska | 68510 | — |
| Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County | Mount Holly | New Jersey | 08060 | — |
| Sparta Cancer Treatment Center | Sparta | New Jersey | 07871 | — |
| Virtua West Jersey Hospital Voorhees | Voorhees Township | New Jersey | 08043 | — |
| Veterans Affairs Western New York Health Care System-Buffalo | Buffalo | New York | 14215 | — |
| Finger Lakes Hematology and Oncology | Clifton Springs | New York | 14432 | — |
| Adirondack Cancer Center | Glens Falls | New York | 12801 | — |
| Glens Falls Hospital | Glens Falls | New York | 12801 | — |
| Orange Regional Medical Center | Middletown | New York | 10940 | — |
| Montefiore Medical Center | The Bronx | New York | 10467-2490 | — |
| Southeastern Medical Oncology Center-Goldsboro | Goldsboro | North Carolina | 27534 | — |
| Margaret R Pardee Memorial Hospital | Hendersonville | North Carolina | 28791 | — |
| Kinston Medical Specialists PA | Kinston | North Carolina | 28501 | — |
| FirstHealth of the Carolinas-Moore Regional Hosiptal | Pinehurst | North Carolina | 28374 | — |
| Rutherford Hospital | Rutherfordton | North Carolina | 28139 | — |
| Bismarck Cancer Center | Bismarck | North Dakota | 58501 | — |
| Mid Dakota Clinic | Bismarck | North Dakota | 58501 | — |
| Saint Alexius Medical Center | Bismarck | North Dakota | 58501 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Altru Cancer Center | Grand Forks | North Dakota | 58201 | — |
| Akron General Medical Center | Akron | Ohio | 44307 | — |
| Mary Rutan Hospital | Bellefontaine | Ohio | 43311 | — |
| Toledo Clinic Cancer Centers-Bowling Green | Bowling Green | Ohio | 43402 | — |
| Mercy Medical Center | Canton | Ohio | 44708 | — |
| Aultman Health Foundation | Canton | Ohio | 44710 | — |
| Adena Regional Medical Center | Chillicothe | Ohio | 45601 | — |
| North Coast Cancer Care-Clyde | Clyde | Ohio | 43410 | — |
| Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| Columbus CCOP | Columbus | Ohio | 43215 | — |
| Grant Medical Center | Columbus | Ohio | 43215 | — |
| Mount Carmel Health Center West | Columbus | Ohio | 43222 | — |
| Doctors Hospital | Columbus | Ohio | 43228 | — |
| Grady Memorial Hospital | Delaware | Ohio | 43015 | — |
| Community Health Partners Regional Medical Center | Elyria | Ohio | 44035 | — |
| Hematology Oncology Center Incorporated | Elyria | Ohio | 44035 | — |
| Fremont Memorial Hospital | Fremont | Ohio | 43420 | — |
| Fairfield Medical Center | Lancaster | Ohio | 43130 | — |
| Lima Memorial Hospital | Lima | Ohio | 45804 | — |
| Mansfield General Hospital-MedCentral Health System | Mansfield | Ohio | 44903 | — |
| Marietta Memorial Hospital | Marietta | Ohio | 45750 | — |
| Saint Luke's Hospital | Maumee | Ohio | 43537 | — |
| Toledo Clinic Cancer Centers-Maumee | Maumee | Ohio | 43537 | — |
| Toledo Radiation Oncology at Northwest Ohio Onocolgy Center | Maumee | Ohio | 43537 | — |
| Knox Community Hospital | Mount Vernon | Ohio | 43050 | — |
| Licking Memorial Hospital | Newark | Ohio | 43055 | — |
| Fisher-Titus Medical Center | Norwalk | Ohio | 44857 | — |
| Saint Charles Hospital | Oregon | Ohio | 43616 | — |
| Toledo Clinic Cancer Centers-Oregon | Oregon | Ohio | 43616 | — |
| Firelands Regional Medical Center | Sandusky | Ohio | 44870 | — |
| North Coast Cancer Care | Sandusky | Ohio | 44870 | — |
| Springfield Regional Medical Center | Springfield | Ohio | 45505 | — |
| Flower Hospital | Sylvania | Ohio | 43560 | — |
| Mercy Hospital of Tiffin | Tiffin | Ohio | 44883 | — |
| The Toledo Hospital/Toledo Children's Hospital | Toledo | Ohio | 43606 | — |
| Saint Vincent Mercy Medical Center | Toledo | Ohio | 43608 | — |
| University of Toledo | Toledo | Ohio | 43614 | — |
| Toledo Community Hospital Oncology Program CCOP | Toledo | Ohio | 43617 | — |
| Mercy Saint Anne Hospital | Toledo | Ohio | 43623 | — |
| Toledo Clinic Cancer Centers-Toledo | Toledo | Ohio | 43623 | — |
| Fulton County Health Center | Wauseon | Ohio | 43567 | — |
| Saint Ann's Hospital | Westerville | Ohio | 43081 | — |
| Genesis HealthCare System | Zanesville | Ohio | 43701 | — |
| Bay Area Hospital | Coos Bay | Oregon | 97420 | — |
| Adventist Medical Center | Portland | Oregon | 97216 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822-2001 | — |
| Mercy Fitzgerald Hospital | Darby | Pennsylvania | 19023-1291 | — |
| Geisinger Medical Center-Cancer Center Hazelton | Hazleton | Pennsylvania | 18201 | — |
| Central PA Hematology-Medical Oncology Associates PC | Lemoyne | Pennsylvania | 17043 | — |
| Riddle Hospital | Media | Pennsylvania | 19063 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Allegheny Cancer Center at Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Hematology and Oncology Associates of North East Pennsylvania | Scranton | Pennsylvania | 18508 | — |
| Geisinger Medical Group | State College | Pennsylvania | 16801 | — |
| Associates In Hematology Oncology PC-Upland | Upland | Pennsylvania | 19013 | — |
| Geisinger Wyoming Valley | Wilkes-Barre | Pennsylvania | 18711 | — |
| AnMed Health Hospital | Anderson | South Carolina | 29621 | — |
| South Carolina Oncology Associates PA | Columbia | South Carolina | 29210 | — |
| Greenville Health System Cancer Institute-Easley | Easley | South Carolina | 29640 | — |
| McLeod Regional Medical Center | Florence | South Carolina | 29506 | — |
| Greenville Health System Cancer Institute-Andrews | Greenville | South Carolina | 29605 | — |
| Greenville Health System Cancer Institute-Butternut | Greenville | South Carolina | 29605 | — |
| Greenville Health System Cancer Institute-Faris | Greenville | South Carolina | 29605 | — |
| Greenville Memorial Hospital | Greenville | South Carolina | 29605 | — |
| Greenville Health System Cancer Instutite/Greenville CCOP | Greenville | South Carolina | 29615 | — |
| Self Regional Healthcare | Greenwood | South Carolina | 29646 | — |
| Cancer Centers of the Carolinas-Greer Medical Oncology | Greer | South Carolina | 29650 | — |
| Greenville Health System Cancer Institute-Greer | Greer | South Carolina | 29650 | — |
| Greenville Health System Cancer Institute-Seneca | Seneca | South Carolina | 29672 | — |
| Spartanburg Regional Medical Center | Spartanburg | South Carolina | 29303 | — |
| Upstate Carolina CCOP | Spartanburg | South Carolina | 29303 | — |
| Greenville Health System Cancer Institute-Spartanburg | Spartanburg | South Carolina | 29307 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| University of Tennessee - Memphis | Memphis | Tennessee | 38163 | — |
| The Don and Sybil Harrington Cancer Center | Amarillo | Texas | 79106 | — |
| Scott and White Memorial Hospital | Temple | Texas | 76508 | — |
| Fredericksburg Oncology Inc | Fredericksburg | Virginia | 22401 | — |
| PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | 98225 | — |
| Harrison HealthPartners Hematology and Oncology-Bremerton | Bremerton | Washington | 98310 | — |
| Columbia Basin Hematology and Oncology PLLC | Kennewick | Washington | 99336 | — |
| Skagit Valley Hospital | Mount Vernon | Washington | 98274 | — |
| Harrison HealthPartners Hematology and Oncology-Poulsbo | Poulsbo | Washington | 98370 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Minor and James Medical PLLC | Seattle | Washington | 98104 | — |
| Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium | Seattle | Washington | 98109 | — |
| Group Health Cooperative-Seattle | Seattle | Washington | 98112 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122-4307 | — |
| The Polyclinic | Seattle | Washington | 98122 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| United General Hospital | Sedro-Woolley | Washington | 98284 | — |
| Cancer Care Northwest - Spokane South | Spokane | Washington | 99202 | — |
| Evergreen Hematology and Oncology PS | Spokane | Washington | 99218 | — |
| Wenatchee Valley Medical Center | Wenatchee | Washington | 98801 | — |
| West Virginia University Charleston | Charleston | West Virginia | 25304 | — |
| Camden-Clark Memorial Hospital | Parkersburg | West Virginia | 26101 | — |
| Midelfort Clinic-Clairemont Campus | Eau Claire | Wisconsin | 54702 | — |
| Mayo Clinic Health System Eau Claire Hospital - Luther Campus | Eau Claire | Wisconsin | 54703 | — |
| Aurora Cancer Care-Southern Lakes | Elkhorn | Wisconsin | 53121 | — |
| Green Bay Oncology at Saint Vincent Hospital | Green Bay | Wisconsin | 54301-3526 | — |
| Saint Vincent Hospital | Green Bay | Wisconsin | 54301 | — |
| Green Bay Oncology Limited at Saint Mary's Hospital | Green Bay | Wisconsin | 54303 | — |
| Saint Mary's Hospital | Green Bay | Wisconsin | 54303 | — |
| Mercy Health System | Janesville | Wisconsin | 53547 | — |
| Holy Family Memorial Hospital | Manitowoc | Wisconsin | 54221 | — |
| Bay Area Medical Center | Marinette | Wisconsin | 54143 | — |
| Columbia Saint Mary's Hospital - Ozaukee | Mequon | Wisconsin | 53097 | — |
| Columbia Saint Mary's Water Tower Medical Commons | Milwaukee | Wisconsin | 53211 | — |
| Medical Consultants Limited | Milwaukee | Wisconsin | 53215 | — |
| Green Bay Oncology - Oconto Falls | Oconto Falls | Wisconsin | 54154 | — |
| Green Bay Oncology - Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235 | — |
| Rocky Mountain Oncology | Casper | Wyoming | 82609 | — |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00499369, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 31, 2014 · Synced Nov 1, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00499369 live on ClinicalTrials.gov.