Phase 2 Proof-of-Concept Study of the Safety and Efficacy of Alfimeprase to Rapidly Open Arteries and Restore Brain Function Following a Stroke
Public ClinicalTrials.gov record NCT00499902. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2, Multicenter, Open-Label, Two-Stage Study to Evaluate the Safety and Efficacy of Intra-Arterial Catheter-Directed Alfimeprase for Restoration of Neurologic Function and Rapid Opening of Arteries in Stroke (CARNEROS-1)
Study identification
- NCT ID
- NCT00499902
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- ARCA Biopharma, Inc.
- Industry
- Enrollment
- 7 participants
Conditions and interventions
Conditions
Interventions
- alfimeprase Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2007
- Primary completion
- Apr 30, 2008
- Completion
- Apr 30, 2008
- Last update posted
- Apr 23, 2008
2007 – 2008
United States locations
- U.S. sites
- 17
- U.S. states
- 12
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Medical Center | Los Angeles | California | 90024 | — |
| Northwestern Medical Center | Chicago | Illinois | 60611 | — |
| Ruan Neurology & Clinical Research Center | Des Moines | Iowa | 50314 | — |
| University of Iowa Hospital | Iowa City | Iowa | 52242 | — |
| University of Iowa Hospital | Iowa City | Iowa | 53342 | — |
| University of Kansas School of Medicine, Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Norton Hospital | Louisville | Kentucky | 40202 | — |
| Michigan State University, Sparrow Hospital | Lansing | Michigan | 48912 | — |
| Albany Medical Center Hospital | Albany | New York | 12208 | — |
| Kalieda Health, MFH | Buffalo | New York | 14203 | — |
| Columbia Presbyterian Medical Center | New York | New York | 10032 | — |
| University of Cincinnati | Cincinnati | Ohio | 45243 | — |
| Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| Oregon Stroke Center | Portland | Oregon | 97239 | — |
| University of Pittsburg Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00499902, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 23, 2008 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00499902 live on ClinicalTrials.gov.