Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia
Public ClinicalTrials.gov record NCT00503581. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase II Evaluation of Continuous Progestin Therapy vs. Sequential Progestin Therapy in the Treatment of Endometrial Intraepithelial Neoplasia (EIN) From a Referred Cohort of Atypical Endometrial Hyperplasia (AEH) or EIN Patients That Desire Uterine Preservation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized phase II trial is studying how well megestrol works in treating patients with endometrial neoplasia or endometrial hyperplasia. Estrogen can cause the growth of endometrial cancer cells. Hormone therapy using megestrol may fight endometrial cancer by blocking the use of estrogen by the abnormal cells.
Study identification
- NCT ID
- NCT00503581
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 9 participants
Conditions and interventions
Interventions
- Biopsy Procedure
- Laboratory Biomarker Analysis Other
- Megestrol Acetate Drug
- Pharmacological Study Other
- Quality-of-Life Assessment Other
- Therapeutic Conventional Surgery Procedure
Procedure · Other · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2007 (Type not available)
- Primary completion
- Jul 2012 (Actual)
- Completion
- Not listed
- Last update posted
- Nov 3, 2020
Started 2007
United States locations
- U.S. sites
- 50
- U.S. states
- 14
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| Olive View-University of California Los Angeles Medical Center | Sylmar | California | 91342 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Saint Francis Hospital and Medical Center | Hartford | Connecticut | 06105 | — |
| The Hospital of Central Connecticut | New Britain | Connecticut | 06050 | — |
| Memorial University Medical Center | Savannah | Georgia | 31404 | — |
| Saint Anthony's Health | Alton | Illinois | 62002 | — |
| Rush - Copley Medical Center | Aurora | Illinois | 60504 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Joliet Oncology-Hematology Associates Limited | Joliet | Illinois | 60435 | — |
| Good Samaritan Regional Health Center | Mount Vernon | Illinois | 62864 | — |
| Carle Clinic-Urbana Main | Urbana | Illinois | 61801 | — |
| Elkhart Clinic | Elkhart | Indiana | 46514-2098 | — |
| Michiana Hematology Oncology PC-Elkhart | Elkhart | Indiana | 46514 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Community Howard Regional Health | Kokomo | Indiana | 46904 | — |
| IU Health La Porte Hospital | La Porte | Indiana | 46350 | — |
| Franciscan Saint Anthony Health-Michigan City | Michigan City | Indiana | 46360 | — |
| Michiana Hematology Oncology PC-Mishawaka | Mishawaka | Indiana | 46545 | — |
| Saint Joseph Regional Medical Center-Mishawaka | Mishawaka | Indiana | 46545 | — |
| Michiana Hematology Oncology PC-Plymouth | Plymouth | Indiana | 46563 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Michiana Hematology Oncology PC-South Bend | South Bend | Indiana | 46601 | — |
| South Bend Clinic | South Bend | Indiana | 46617 | — |
| Northern Indiana Cancer Research Consortium CCOP | South Bend | Indiana | 46628 | — |
| Michiana Hematology Oncology-PC Westville | Westville | Indiana | 46391 | — |
| Gynecologic Oncology of West Michigan PLLC | Grand Rapids | Michigan | 49546 | — |
| Michiana Hematology Oncology PC-Niles | Niles | Michigan | 49120 | — |
| Lakeland Hospital | Saint Joseph | Michigan | 49085 | — |
| Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | — |
| Southeast Missouri Hospital | Cape Girardeau | Missouri | 63701 | — |
| Saint Francis Medical Center | Cape Girardeau | Missouri | 63703 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield | Springfield | Missouri | 65804 | — |
| Saint Louis Cancer and Breast Institute-South City | St Louis | Missouri | 63109 | — |
| Saint John's Mercy Medical Center | St Louis | Missouri | 63141 | — |
| Saint Louis-Cape Girardeau CCOP | St Louis | Missouri | 63141 | — |
| Women's Cancer Center of Nevada | Las Vegas | Nevada | 89169 | — |
| State University of New York Downstate Medical Center | Brooklyn | New York | 11203 | — |
| Montefiore Medical Center-Einstein Campus | The Bronx | New York | 10461 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| FirstHealth of the Carolinas-Moore Regional Hosiptal | Pinehurst | North Carolina | 28374 | — |
| Mount Carmel Health Center West | Columbus | Ohio | 43222 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Cancer Care Associates-Midtown | Tulsa | Oklahoma | 74104 | — |
| Tulsa Cancer Institute | Tulsa | Oklahoma | 74146 | — |
| Virginia Commonwealth University/Massey Cancer Center | Richmond | Virginia | 23298 | — |
| Columbia Saint Mary's Hospital - Ozaukee | Mequon | Wisconsin | 53097 | — |
| Columbia Saint Mary's Water Tower Medical Commons | Milwaukee | Wisconsin | 53211 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00503581, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 3, 2020 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00503581 live on ClinicalTrials.gov.