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Terminated Phase 2 Interventional

Safety and Efficacy Study of KP-1461 to Treat ART-Experienced HIV+ Patients

ClinicalTrials.gov ID: NCT00504452

Public ClinicalTrials.gov record NCT00504452. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 13, 2026, 4:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label, Multicenter, Mechanism Validation Study to Evaluate the Safety, Efficacy and Tolerability of KP-1461 as Monotherapy for 124 Days in Antiretroviral-experienced, HIV-1-infected Subjects

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary purpose of the study is to investigate the safety and efficacy of KP-1461 given every 12 hours for 124 days to HIV+ patients who have failed multiple antiretroviral regimens.

Study identification

NCT ID
NCT00504452
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Koronis Pharmaceuticals.
Industry
Enrollment
27 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 30, 2007
Primary completion
Aug 31, 2008
Completion
May 31, 2009
Last update posted
Nov 6, 2011

2007 – 2009

United States locations

U.S. sites
30
U.S. states
19
U.S. cities
28
Facility City State ZIP Site status
Health for Life Clinic Little Rock Arkansas 72207
Living Hope Clinical Foundation Long Beach California 90813
Light Source Medical/U. of Southern California Los Angeles California 90036
ACTU at CARES/UC Davis Sacramento California 95817
UCSD Antiviral Research Center San Diego California 92103
Quest Clinical Research San Francisco California 94115
Dupont Circle Physician's Group Washington D.C. District of Columbia 20009
Whitman-Walker Clinic Washington D.C. District of Columbia 20009
Comprehensive Care Center -- HIV Clinical Research Fort Lauderdale Florida 33311
Wohlfeiler, Piperato and Associates, LLC North Miami Beach Florida 33169
Orlando Immunology Center Orlando Florida 32803
Treasure Coast Infectious Disease Consultants Vero Beach Florida 32960
AIDS Research Consortium of Atlanta Atlanta Georgia 30308
Northstar Medical Center Chicago Illinois 60657
University of Kansas School of Medicine - PriVia, The Research Centers of Via Christi Wichita Kansas 67214
Institute of Human Virology, University of Maryland Baltimore Maryland 21201
Community Research Initiative of New England Boston Massachusetts 02215
Dybedal Center for Clinical Research, Kansas City University of Medicine and Biosciences Kansas City Missouri 64106
St. Michael's Medical Center Newark New Jersey 07102
Southwest CARE Center Santa Fe New Mexico 87505
Albany Medical College Albany New York 12208
AIDS Community Research Initiative of America New York New York 10018
Mount Sinai Medical Center New York New York 10029
Duke University Medical Center Durham North Carolina 27710
University of Cincinnati Medical Center Cincinnati Ohio 45267
Thomas Jefferson University, Division of Infectious Disease Philadelphia Pennsylvania 19107
Charlton Methodist Hospital Dallas Texas 75204
University of Texas Health Science Center Houston Texas 77030
CARE-ID Annandale Virginia 22003
University of Washington AIDS Clinical Trials Unit Seattle Washington 98104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00504452, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 6, 2011 · Synced Sep 13, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00504452 live on ClinicalTrials.gov.

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