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Completed Phase 2 Interventional Results available

Intravenous CTLA4-lg Treatment in Recent Onset Type 1 Diabetes Mellitus

ClinicalTrials.gov ID: NCT00505375

Public ClinicalTrials.gov record NCT00505375. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 30, 2026, 12:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Effects of CTLA-4 Ig (Abatacept) On The Progression of Type 1 Diabetes In New Onset Subjects

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine whether treatment with CTLA4-Ig (Abatacept) in individuals with new onset T1DM will improve insulin secretion (C-peptide production) compared to placebo.

Study identification

NCT ID
NCT00505375
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
112 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
6 Years to 45 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 2008 (Actual)
Primary completion
May 2012 (Actual)
Completion
May 2012 (Actual)
Last update posted
May 6, 2020

2008 – 2012

United States locations

U.S. sites
12
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
Childrens Hospital Los Angeles Los Angeles California 90027 —
University of California - San Francisco San Francisco California 94143 —
Stanford University Stanford California 94305 —
The Barbara Davis Center for Childhood Diabetes Aurora Colorado 80045 —
University of Florida Gainesville Florida 32610-0296 —
University of Miami Miami Florida 33136 —
Joslin Diabetes Center Boston Massachusetts 02215 —
University of Minnesota Minneapolis Minnesota 55455 —
Columbia University, Naomi Berrie Diabetes Center New York New York 10032 —
University of Pittsburgh, Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15213 —
University of Texas, Southwestern Medical School Dallas Texas 75235-8858 —
Benaroya Research Institute Seattle Washington 98101 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00505375, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 6, 2020 · Synced Sep 30, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00505375 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →