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Vascular Endothelial Growth Factor VEGF Trap-Eye:Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration(AMD)

ClinicalTrials.gov ID: NCT00509795

Public ClinicalTrials.gov record NCT00509795. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 22, 2026, 9:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double Masked, Active Controlled Phase III Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal VEGF Trap in Subjects With Neovascular Age-Related Macular Degeneration

Study identification

NCT ID
NCT00509795
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Regeneron Pharmaceuticals
Industry
Enrollment
1,217 participants

Conditions and interventions

Interventions

  • ranibizumab Biological
  • aflibercept injection (VEGF Trap-Eye, BAY86-5321) Biological

Biological

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2007
Primary completion
Aug 31, 2010
Completion
Jun 30, 2011
Last update posted
Dec 27, 2012

2007 – 2011

United States locations

U.S. sites
176
U.S. states
41
U.S. cities
147
Facility City State ZIP Site status
Not listed Birmingham Alabama 35205 —
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Not listed Loma Linda California 92354 —
Not listed Los Angeles California 90033 —
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Not listed Menlo Park California 94025 —
Not listed Mountain View California 94040 —
Not listed Oakland California 94609 —
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Not listed Fort Wayne Indiana 46804 —
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Not listed New Albany Indiana 47150 —
Not listed Iowa City Iowa 52242-1091 —
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Not listed New Orleans Louisiana 70115 —
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Not listed Shreveport Louisiana 71105 —
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Not listed Chevy Chase Maryland 20815 —
Not listed Hagerstown Maryland 21740 —
Not listed Towson Maryland 21204 —
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Not listed Lawrenceville New Jersey 08648 —
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Not listed Toms River New Jersey 08753 —
Not listed Albuquerque New Mexico 87106 —
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Not listed Lynbrook New York 11563 —
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Not listed Poughkeepsie New York 12601 —
Not listed Rochester New York 14620 —
Not listed Rochester New York 14642 —
Not listed Slingerlands New York 12159 —
Not listed Syracuse New York 13224 —
Not listed Asheville North Carolina 28803 —
Not listed Charlotte North Carolina 28210 —
Not listed Raleigh North Carolina 27607 —
Not listed Southern Pines North Carolina 28387 —
Not listed Winston-Salem North Carolina 27157 —
Not listed Cincinnati Ohio 45202 —
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Not listed Toledo Ohio 43608 —
Not listed Oklahoma City Oklahoma 73104 —
Not listed Ashland Oregon 97520 —
Not listed Portland Oregon 97210 —
Not listed Portland Oregon 97227 —
Not listed Salem Oregon 97302 —
Not listed Kingston Pennsylvania 18704 —
Not listed Philadelphia Pennsylvania 19104 —
Not listed Philadelphia Pennsylvania 19107 —
Not listed Philadelphia Pennsylvania 19124 —
Not listed Pittsberg Pennsylvania 15231 —
Not listed Pittsburgh Pennsylvania 15212 —
Not listed Pittsburgh Pennsylvania 15213 —
Not listed West Mifflin Pennsylvania 15122 —
Not listed Wyomissing Pennsylvania 19610 —
Not listed Providence Rhode Island 02903-4928 —
Not listed Charleston South Carolina 29414 —
Not listed Columbia South Carolina 29223 —
Not listed Greenville South Carolina 29605 —
Not listed West Columbia South Carolina 29169 —
Not listed Rapid City South Dakota 57701 —
Not listed Memphis Tennessee 38119 —
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Not listed Nashville Tennessee 37203 —
Not listed Abilene Texas 79606 —
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Not listed Corpus Cristi Texas 78413 —
Not listed Dallas Texas 75390 —
Not listed DeSoto Texas 75115 —
Not listed Fort Worth Texas 76102 —
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Not listed Galveston Texas 77555 —
Not listed Houston Texas 77030 —
Not listed McAllen Texas 78503 —
Not listed Odessa Texas 79761 —
Not listed San Antonio Texas 78240 —
Not listed Salt Lake City Utah 84107 —
Not listed Salt Lake City Utah 84132 —
Not listed Burlington Vermont 05401 —
Not listed Charlottesville Virginia 22908 —
Not listed Fairfax Virginia 22031 —
Not listed Richmond Virginia 23221 —
Not listed Seattle Washington 98104 —
Not listed Silverdale Washington 98383 —
Not listed Madison Wisconsin 53715 —
Not listed Madison Wisconsin 58705 —
Not listed Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00509795, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 27, 2012 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00509795 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →