A Study for Patients With Complicated Skin and Skin Structure Infections
Public ClinicalTrials.gov record NCT00514527. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Nuvocid® (Oritavancin) at Single or Infrequent Doses for the Treatment of Complicated Skin and Skin Structure Infections (SIMPLIFI)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Two Phase III trials to demonstrate the efficacy and safety of oritavancin in the treatment of complicated skin and skin structure infections (cSSSI) have been completed. The pharmacokinetic profile of oritavancin in humans suggests that oritavancin has the potential to be used safely and effectively when given either as a single dose or as an infrequent dose for cSSSI. Data from animals support this theory. SIMPLIFI has been designed to evaluate the efficacy and safety of either a single dose of oritavancin or an infrequent dose of oritavancin (First dose on Day one with an option for a second dose on Day five) compared to the previously studied dosing regimen of 200mg oritavancin given once daily for 3 to 7 days.
Study identification
- NCT ID
- NCT00514527
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 294 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2007 (Type not available)
- Primary completion
- Apr 2008 (Actual)
- Completion
- May 2008 (Actual)
- Last update posted
- Aug 14, 2008
2007 – 2008
United States locations
- U.S. sites
- 33
- U.S. states
- 15
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Targanta Recruiting Site | Mobile | Alabama | 36617 | — |
| Targanta Recruiting Site | Anaheim | California | 92804 | — |
| Targanta Recruiting Site | Buena Park | California | 90620 | — |
| Targanta Recruiting Site | Chula Vista | California | 91911 | — |
| Targanta Recruiting Site | Hawaiian Gardens | California | 90716 | — |
| Targanta Recruiting Site | Long Beach | California | 90813 | — |
| Targanta Recruiting Site | Los Angeles | California | 90015 | — |
| Targanta Recruiting Site | Oceanside | California | 92056 | — |
| Targanta Recruiting Site | Rolling Hills Estates | California | 90274 | — |
| Targanta Recruiting Site | San Jose | California | 95124 | — |
| Targanta Recruiting Site | Torrance | California | 90509 | — |
| Targanta Recruiting Site | Atlantis | Florida | 33462 | — |
| Targanta Recruiting Site | Inverness | Florida | 34452 | — |
| Targanta Recruiting Site | Miami | Florida | 33136 | — |
| Targanta Recruiting Site | Columbus | Georgia | 31405 | — |
| Targanta Recruiting Site | Marietta | Georgia | 30060 | — |
| Targanta Recruiting Site | Savannah | Georgia | 31405 | — |
| Targanta Recruiting Site | Springfield | Illinois | 602701 | — |
| Targanta Recruiting Site | Indianapolis | Indiana | 46280 | — |
| Targanta Recruiting Site | Baton Rouge | Louisiana | 70808 | — |
| Targanta Recruiting Site | Lafayette | Louisiana | 70503 | — |
| Targanta Recruiting Site | New Orleans | Louisiana | 70112 | — |
| Targanta Recruiting Site | Cumberland | Maryland | 21502 | — |
| Targanta Recruiting Site | Detroit | Michigan | 48202 | — |
| Targanta Recruiting Site | Minneapolis | Minnesota | 55422 | — |
| Targanta Recruiting Site | Albany | New York | 12208-1901 | — |
| Targanta Recruiting Site | Columbus | Ohio | 43215 | — |
| Targanta Recruiting Site | Toledo | Ohio | 43608 | — |
| Targanta Recruiting Site | Jackson | Tennessee | 38301 | — |
| Targanta Recruiting Site | Arlington | Texas | 76012 | — |
| Targanta Recruiting Site | Houston | Texas | 77005 | — |
| Targanta Recruiting Site | Houston | Texas | 77055 | — |
| Targanta Recruiting Site | Salt Lake City | Utah | 84102 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 33 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00514527, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 14, 2008 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00514527 live on ClinicalTrials.gov.