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Completed Phase 2 Interventional

Study of XL647 in Subjects With NSCLC Who Have Progressed After Responding to Treatment With Gefitinib or Erlotinib

ClinicalTrials.gov ID: NCT00522145

Public ClinicalTrials.gov record NCT00522145. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 8:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study of XL647 in Subjects With Non-Small Cell Lung Cancer Who Have Progressed After Responding to Treatment With Either Gefitinib or Erlotinib

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine the best confirmed response rate of daily administration of the multiple receptor tyrosine kinase (RTK) inhibitor (including EGFR and VEGFR2) XL647 in subjects with NSCLC who have progressed after responding to treatment with either erlotinib or gefitinib.

Study identification

NCT ID
NCT00522145
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Kadmon Corporation, LLC
Industry
Enrollment
41 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2007
Primary completion
Sep 30, 2009
Completion
Jan 31, 2010
Last update posted
May 12, 2022

2007 – 2010

United States locations

U.S. sites
10
U.S. states
7
U.S. cities
10
Facility City State ZIP Site status
Ronald Yanagihara Gilroy California 95020
University of California Davis Cancer Center Sacramento California 95817
Oncology Division and General Clincial Research, Stanford University Medical Center Stanford California 94305
Cancer Care Center, Inc. P.C. New Albany Indiana 47150
Washington County Hospital, The Center for Clinical Research Hagerstown Maryland 21740
Wayne State University, Wertz Clinical Cancer Center, Karmanos Center Detroit Michigan 48201
Memorial Sloan-Kettering Cancer Center New York New York 10021
New Bern Cancer Care Oncology New Bern North Carolina 28560
Case Western Reserve University, University Hospitals of Cleveland Cleveland Ohio 44106
Signal Point Clinical Research Center Middletown Ohio 45042

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00522145, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 12, 2022 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00522145 live on ClinicalTrials.gov.

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