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Completed Phase 2 Interventional Results available

Randomized, Single-Masked, Long-Term, Safety and Tolerability Study of VEGF Trap-Eye in AMD

ClinicalTrials.gov ID: NCT00527423

Public ClinicalTrials.gov record NCT00527423. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 5:20 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Single-Masked , Long-Term, Safety and Tolerability Study of Intravitreal VEGF Trap-Eye in Subjects With Neovascular Age-related Macular Degeneration

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Rollover study for subjects in prior VEGF Trap-Eye Phase I and II studies. Primary objective is to assess long-term safety and tolerability of continuing intravitreal treatment in subjects with wet age-related macular degeneration.

Study identification

NCT ID
NCT00527423
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Regeneron Pharmaceuticals
Industry
Enrollment
157 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2007 (Type not available)
Primary completion
Oct 2011 (Actual)
Completion
Oct 2011 (Actual)
Last update posted
Jun 12, 2013

2007 – 2011

United States locations

U.S. sites
33
U.S. states
18
U.S. cities
33
Facility City State ZIP Site status
Not listed Peoria Arizona 85381 —
Not listed Phoenix Arizona 85020 —
Not listed Tucson Arizona 85704 —
Not listed Beverly Hills California 90211 —
Not listed Loma Linda California 92354 —
Not listed Palm Springs California 92262 —
Not listed Pasadena California 91105 —
Not listed Poway California 92064 —
Not listed Westlake Village California 91361 —
Not listed Fort Myers Florida 33912 —
Not listed Stuart Florida 34994 —
Not listed Winter Haven Florida 33880 —
Not listed Augusta Georgia 30909 —
Not listed Glenview Illinois 60026 —
Not listed Indianapolis Indiana 47280 —
Not listed Baltimore Maryland 21287 —
Not listed Hagerstown Maryland 21740 —
Not listed Boston Massachusetts 02114 —
Not listed West Springfield Massachusetts 01089 —
Not listed Toms River New Jersey 08755 —
Not listed Lynbrook New York 11563 —
Not listed Charlotte North Carolina 28210 —
Not listed Oklahoma City Oklahoma 73104 —
Not listed Portland Oregon 97210 —
Not listed West Columbia South Carolina 29169 —
Not listed Rapid City South Dakota 57701 —
Not listed Nashville Tennessee 37203 —
Not listed Austin Texas 78705 —
Not listed Fort Worth Texas 76102 —
Not listed Houston Texas 77030 —
Not listed McAllen Texas 78503 —
Not listed San Antonio Texas 78240 —
Not listed Salt Lake City Utah 84107 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00527423, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 12, 2013 · Synced Oct 26, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00527423 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →