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Completed Phase 3 Interventional Results available

AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease

ClinicalTrials.gov ID: NCT00528424

Public ClinicalTrials.gov record NCT00528424. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:30 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Open-Label Extension Study of the Safety and Efficacy of AA4500 in the Treatment of Subjects With Advanced Dupuytren's Disease

Study identification

NCT ID
NCT00528424
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Enrollment
286 participants

Conditions and interventions

Interventions

  • AA4500 Biological

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2007
Primary completion
Oct 31, 2008
Completion
Oct 31, 2008
Last update posted
Dec 1, 2017

2007 – 2008

United States locations

U.S. sites
15
U.S. states
11
U.S. cities
15
Facility City State ZIP Site status
100 UCLA Medical Plaza, Suite 305 Los Angeles California 90095
Hand Surgery Clinic Palo Alto California 94304
Hand Surgery Associates, PC Denver Colorado 80210
The Hand and Upper Extremity Center of Georgia, P.C. Atlanta Georgia 30342
Rockford Orthopedic Associates, Ltd. Rockford Illinois 61107
The Indiana Hand Center Indianapolis Indiana 46260
Brigham and Women's Hospital, Department of Orthopedic Surgery Boston Massachusetts 02115
Newton-Wellesley Hospital Newton Massachusetts 02462
TRIA Orthopaedic Center Minneapolis Minnesota 55431
Hospital for Special Surgery New York New York 10021
SUNY Stony Brook - Department of Orthopedics Stony Brook New York 11794
Health Research Institute Oklahoma City Oklahoma 73109
Hand Microsurgery & Reconstructive Orthopaedics Erie Pennsylvania 16550
University Orthopedics Center State College Pennsylvania 16801
Department of Orthopaedics, Brown University, Rhode Island Hospital Providence Rhode Island 02905

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00528424, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 1, 2017 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00528424 live on ClinicalTrials.gov.

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