AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Dupuytren's Contracture
Public ClinicalTrials.gov record NCT00528606. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Efficacy of AA4500 in the Treatment of Subjects With Dupuytren's Contracture
Study identification
- NCT ID
- NCT00528606
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Endo USA Inc., a Keenova Therapeutics Company
- Industry
- Enrollment
- 308 participants
Conditions and interventions
Conditions
Interventions
- collagenase clostridium histolyticum Biological
- Placebo Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2007
- Primary completion
- Mar 31, 2008
- Completion
- Mar 31, 2008
- Last update posted
- Dec 1, 2017
2007 – 2008
United States locations
- U.S. sites
- 15
- U.S. states
- 11
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| 100 UCLA Medical Plaza, Suite 305 | Los Angeles | California | 90095 | — |
| Hand Surgery Clinic | Palo Alto | California | 94304 | — |
| Hand Surgery Associates, PC | Denver | Colorado | 80210 | — |
| The Hand and Upper Extremity Center of Georgia, P.C. | Atlanta | Georgia | 30342 | — |
| Rockford Orthopedic Associates, Ltd. | Rockford | Illinois | 61107 | — |
| The Indiana Hand Center | Indianapolis | Indiana | 46260 | — |
| Brigham and Women's Hospital, Department of Orthopedic Surgery | Boston | Massachusetts | 02115 | — |
| Newton-Wellesley Hospital | Newton | Massachusetts | 02462 | — |
| TRIA Orthopaedic Center | Minneapolis | Minnesota | 55431 | — |
| Hospital for Special Surgery | New York | New York | 10021 | — |
| SUNY Stony Brook - Department of Orthopedics | Stony Brook | New York | 11794 | — |
| Health Research Institute | Oklahoma City | Oklahoma | 73109 | — |
| Hand Microsurgery & Reconstructive Orthopaedics | Erie | Pennsylvania | 16550 | — |
| University Orthopedics Center | State College | Pennsylvania | 16801 | — |
| Department of Orthopaedics, Brown University, Rhode Island Hospital | Providence | Rhode Island | 02905 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00528606, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 1, 2017 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00528606 live on ClinicalTrials.gov.