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Completed Phase 3 Interventional Results available

Safety and Efficacy Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease

ClinicalTrials.gov ID: NCT00528840

Public ClinicalTrials.gov record NCT00528840. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Open-Label Study of the Safety and Efficacy of AA4500 in the Treatment of Subjects With Advanced Dupuytren's Disease

Study identification

NCT ID
NCT00528840
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Enrollment
201 participants

Conditions and interventions

Interventions

  • collagenase clostridium histolyticum Biological

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2007
Primary completion
Sep 30, 2008
Completion
Sep 30, 2008
Last update posted
Dec 1, 2017

2007 – 2008

United States locations

U.S. sites
14
U.S. states
11
U.S. cities
13
Facility City State ZIP Site status
Hope Research Institute Phoenix Arizona 85050
Tucson Orthopedic Institute, P.C. Tucson Arizona 85172
Providence Clinical Research Burbank California 91505
Southern Illinois Hand Center, S.C. Effingham Illinois 62401
Rockford Orthopedic Associates, Ltd. Rockford Illinois 61107
The Indiana Hand Center Indianapolis Indiana 46260
Pri Via Wichita Kansas 67214
St. Alexius Medical Center Bismarck North Dakota 58501
David R. Mandel, Inc. Mayfield Ohio 44143
St. Vincent Medical Center Portland Oregon 97225
Hamot Center for Clinical Research Erie Pennsylvania 16550
Alpha Clinical Research Clarksville Tennessee 37043
The Rheumatic Disease Clinic of Houston Houston Texas 77004
Accurate Clincal Research Houston Texas 77034

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00528840, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 1, 2017 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00528840 live on ClinicalTrials.gov.

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