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Completed Phase 2 Interventional

Proof of Concept Study of Cognitive Improvement in Patients With Schizophrenia

ClinicalTrials.gov ID: NCT00528905

Public ClinicalTrials.gov record NCT00528905. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 26, 2026, 2:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center Randomized, Placebo-Controlled, Double-Blind, Parallel Group, Phase IIb Proof of Concept Study With 3 Oral Groups of AZD3480 During 12 Weeks Treatment of Cognitive Deficits in Patients With Schizophrenia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to demonstrate that AZD3480 improves cognition in patients with stable schizophrenia who are being treated with an atypical antipsychotic and who are active cigarette smokers, to assess the safety and tolerability of AZD3480 and to define the optimal dose(s) to be used in future trials.

Study identification

NCT ID
NCT00528905
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
400 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2007
Primary completion
Sep 30, 2008
Completion
Oct 31, 2008
Last update posted
Nov 24, 2008

2007 – 2008

United States locations

U.S. sites
66
U.S. states
25
U.S. cities
66
Facility City State ZIP Site status
Research Site Little Rock Arkansas — —
Research Site Anaheim California — —
Research Site Cerritos California — —
Research Site Costa Mesa California — —
Research Site Escondido California — —
Research Site Garden Grove California — —
Research Site Long Beach California — —
Research Site Los Angeles California — —
Research Site Oceanside California — —
Research Site Pasadena California — —
Research Site Pico Rivera California — —
Research Site San Diego California — —
Research Site Santa Ana California — —
Research Site New Britain Connecticut — —
Research Site New Haven Connecticut — —
Research Site Washington D.C. District of Columbia — —
Research Site Boca Raton Florida — —
Research Site Coral Gables Florida — —
Research Site North Miami Florida — —
Research Site Orlando Florida — —
Research Site Tampa Florida — —
Research Site Atlanta Georgia — —
Research Site Augusta Georgia — —
Research Site Marietta Georgia — —
Research Site Chicago Illinois — —
Research Site Joliet Illinois — —
Research Site Schaumburg Illinois — —
Research Site Indianapolis Indiana — —
Research Site New Orleans Louisiana — —
Research Site Glen Burnie Maryland — —
Research Site Haverhill Massachusetts — —
Research Site Pittsfield Massachusetts — —
Research Site Minneapolis Minnesota — —
Research Site St Louis Missouri — —
Research Site Las Vegas Nevada — —
Research Site Nashua New Hampshire — —
Research Site Cherry Hill New Jersey — —
Research Site Clementon New Jersey — —
Research Site East Orange New Jersey — —
Research Site Newark New Jersey — —
Research Site Paramus New Jersey — —
Research Site Brooklyn New York — —
Research Site Cedarhurst New York — —
Research Site Elmsford New York — —
Research Site Glen Oaks New York — —
Research Site Jamaica New York — —
Research Site New York New York — —
Research Site Rochester New York — —
Research Site Staten Island New York — —
Research Site Cincinnati Ohio — —
Research Site Columbus Ohio — —
Research Site Kettering Ohio — —
Research Site Oklahoma City Oklahoma — —
Research Site Allentown Pennsylvania — —
Research Site DuBois Pennsylvania — —
Research Site Norristown Pennsylvania — —
Research Site Philadelphia Pennsylvania — —
Research Site Charleston South Carolina — —
Research Site Memphis Tennessee — —
Research Site Austin Texas — —
Research Site DeSoto Texas — —
Research Site Houston Texas — —
Research Site Irving Texas — —
Research Site San Antonio Texas — —
Research Site Richmond Virginia — —
Research Site Spokane Washington — —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00528905, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 24, 2008 · Synced Sep 26, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00528905 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →