A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair
Public ClinicalTrials.gov record NCT00528970. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of Intravenous Methylnaltrexone (MOA-728) for the Treatment of Post Operative Ileus After Ventral Hernia Repair
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the safety and efficacy of two different dose regimens (12 milligrams \[mg\] and 24 mg) of IV MOA-728 versus placebo in shortening the time to return of bowel function in participants receiving opioid analgesia administered via patient-controlled anesthesia (PCA), and who had undergone repair of large (greater than or equal to \[≥\]10 centimeters) ventral hernias with or without a mesh prosthesis via laparotomy or laparoscopy.
Study identification
- NCT ID
- NCT00528970
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 374 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 17, 2007 (Actual)
- Primary completion
- Feb 5, 2008 (Actual)
- Completion
- Feb 5, 2008 (Actual)
- Last update posted
- Sep 4, 2019
2007 – 2008
United States locations
- U.S. sites
- 75
- U.S. states
- 30
- U.S. cities
- 65
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Benton | Arkansas | 72015 | — |
| Not listed | Colton | California | 92324 | — |
| Not listed | Laguna Hills | California | 92653 | — |
| Not listed | Loma Linda | California | 92354 | — |
| Not listed | Long Beach | California | 90806 | — |
| Not listed | Los Angeles | California | 90033 | — |
| Not listed | Orange | California | 92868 | — |
| Not listed | San Jose | California | 95124 | — |
| Not listed | Santa Barbara | California | 93105 | — |
| Not listed | Denver | Colorado | 80218 | — |
| Not listed | Denver | Colorado | 80220 | — |
| Not listed | Inverness | Florida | 34452 | — |
| Not listed | Jacksonville | Florida | 32216 | — |
| Not listed | Jacksonville | Florida | 32224 | — |
| Not listed | Melbourne | Florida | 32901 | — |
| Not listed | Miami | Florida | 33136 | — |
| Not listed | Miami | Florida | 33156 | — |
| Not listed | Naples | Florida | 34119 | — |
| Not listed | Orlando | Florida | 32804 | — |
| Not listed | Pensacola | Florida | 32504 | — |
| Not listed | Tampa | Florida | 33606 | — |
| Not listed | Peoria | Illinois | 61603 | — |
| Not listed | Des Moines | Iowa | 50309 | — |
| Not listed | Kansas City | Kansas | 66160 | — |
| Not listed | Lexington | Kentucky | 40536 | — |
| Not listed | Baltimore | Maryland | 21201 | — |
| Not listed | Boston | Massachusetts | 02118 | — |
| Not listed | Boston | Massachusetts | 02215 | — |
| Not listed | Springfield | Massachusetts | 01199 | — |
| Not listed | Ann Arbor | Michigan | 48109-5048 | — |
| Not listed | Detroit | Michigan | 48201 | — |
| Not listed | Flint | Michigan | 48503 | — |
| Not listed | Jackson | Mississippi | 39202 | — |
| Not listed | Columbia | Missouri | 65212 | — |
| Not listed | Omaha | Nebraska | 68124 | — |
| Not listed | Omaha | Nebraska | 68131 | — |
| Not listed | New Brunswick | New Jersey | 08903 | — |
| Not listed | Albuquerque | New Mexico | 87106 | — |
| Not listed | Albany | New York | 12208 | — |
| Not listed | New York | New York | 10016 | — |
| Not listed | Stony Brook | New York | 11794-8480 | — |
| Not listed | Syracuse | New York | 13210 | — |
| Not listed | The Bronx | New York | 10467 | — |
| Not listed | Chapel Hill | North Carolina | 27599-7081 | — |
| Not listed | Durham | North Carolina | 27710 | — |
| Not listed | Winston-Salem | North Carolina | 27103 | — |
| Not listed | Winston-Salem | North Carolina | 27157 | — |
| Not listed | Cincinnati | Ohio | 45267 | — |
| Not listed | Cleveland | Ohio | 44109 | — |
| Not listed | Columbus | Ohio | 43210 | — |
| Not listed | Oklahoma City | Oklahoma | 73104 | — |
| Not listed | Bend | Oregon | 97701 | — |
| Not listed | Portland | Oregon | 97239 | — |
| Not listed | Hershey | Pennsylvania | 17033 | — |
| Not listed | Philadelphia | Pennsylvania | 19102 | — |
| Not listed | Philadelphia | Pennsylvania | 19104 | — |
| Not listed | Philadelphia | Pennsylvania | 19107-5092 | — |
| Not listed | Philadelphia | Pennsylvania | 19140 | — |
| Not listed | Pittsburgh | Pennsylvania | 15213 | — |
| Not listed | Pittsburgh | Pennsylvania | 15232 | — |
| Not listed | Sellersville | Pennsylvania | 18960 | — |
| Not listed | Providence | Rhode Island | 02906 | — |
| Not listed | Sioux Falls | South Dakota | 57105 | — |
| Not listed | Knoxville | Tennessee | 37934 | — |
| Not listed | Memphis | Tennessee | 38103 | — |
| Not listed | Nashville | Tennessee | 37212 | — |
| Not listed | Fort Worth | Texas | 76135 | — |
| Not listed | San Antonio | Texas | 78229 | — |
| Not listed | Temple | Texas | 76508 | — |
| Not listed | Norfolk | Virginia | 23507 | — |
| Not listed | Winchester | Virginia | 22601 | — |
| Not listed | Bellevue | Washington | 98005 | — |
| Not listed | Tacoma | Washington | 98405 | — |
| Not listed | Morgantown | West Virginia | 26506 | — |
| Not listed | Milwaukee | Wisconsin | 53295 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00528970, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 4, 2019 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00528970 live on ClinicalTrials.gov.