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Completed Phase 3 Interventional Results available

Study Evaluating Subcutaneous MOA-728 for the Treatment of Opioid-Induced Constipation (OIC) in Subjects With Chronic Non-Malignant Pain

ClinicalTrials.gov ID: NCT00529087

Public ClinicalTrials.gov record NCT00529087. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 10:14 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Mulitcenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of Subcutaneous MOA-728 for the Treatment of Opioid-Induced Constipation in Subjects With Chronic Non-Malignant Pain

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary purpose of the protocol is to evaluate the safety, efficacy, and tolerability of subcutaneous MOA-728 versus placebo in subjects with chronic non-malignant pain who have Opioid-Induced Constipation (OIC).

Study identification

NCT ID
NCT00529087
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Bausch Health Americas, Inc.
Industry
Enrollment
460 participants

Conditions and interventions

Conditions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2007 (Type not available)
Primary completion
Dec 2008 (Actual)
Completion
Dec 2008 (Actual)
Last update posted
Nov 25, 2019

2007 – 2008

United States locations

U.S. sites
78
U.S. states
30
U.S. cities
72
Facility City State ZIP Site status
Not listed Mobile Alabama 36606 —
Not listed Mobile Alabama 36608 —
Not listed Sun City Arizona 85351 —
Not listed Tucson Arizona 85710 —
Not listed Tucson Arizona 85741 —
Not listed Hot Springs Arkansas 71913 —
Not listed Anaheim California 92801 —
Not listed Garden Grove California 92843 —
Not listed Hawaiian Gardens California 90716 —
Not listed Long Beach California 90813 —
Not listed Los Angeles California 90048 —
Not listed San Diego California 92121 —
Not listed Brandon Florida 33511 —
Not listed Cheifland Florida 32626 —
Not listed Clearwater Florida 33756 —
Not listed Gainesville Florida 32607 —
Not listed Jacksonville Florida 32216 —
Not listed Jupiter Florida 33458 —
Not listed Largo Florida 33770 —
Not listed Miami Florida 33180 —
Not listed Naples Florida 34104 —
Not listed Ocala Florida 34471 —
Not listed Ocala Florida 34474 —
Not listed Orlando Florida 32806 —
Not listed Ormond Beach Florida 32174 —
Not listed Spring Hill Florida 34609 —
Not listed Tampa Florida 33603 —
Not listed West Palm Beach Florida 33409 —
Not listed Winter Park Florida 32789 —
Not listed Atlanta Georgia 30329 —
Not listed Marietta Georgia 30060 —
Not listed Stockbridge Georgia 30281 —
Not listed Chicago Illinois 60610 —
Not listed DeKalb Illinois 60115 —
Not listed Avon Indiana 46123 —
Not listed Indianapolis Indiana 46250 —
Not listed West Des Moines Iowa 50265 —
Not listed Shreveport Louisiana 71105 —
Not listed Sunset Louisiana 70584 —
Not listed Elkridge Maryland 21075 —
Not listed Boston Massachusetts 02115 —
Not listed Brockton Massachusetts 02301 —
Not listed Cadillac Michigan 49601 —
Not listed Paw Paw Michigan 49079 —
Not listed Traverse City Michigan 49684 —
Not listed Biloxi Mississippi 39531 —
Not listed Ocean Springs Mississippi 39564 —
Not listed Nixa Missouri 65719 —
Not listed Kalispell Montana 59901 —
Not listed Missoula Montana 59808 —
Not listed Omaha Nebraska 68114 —
Not listed Las Vegas Nevada 89119 —
Not listed Albuquerque New Mexico 87102 —
Not listed Great Neck New York 11023 —
Not listed Valley Stream New York 11580 —
Not listed Charlotte North Carolina 28204 —
Not listed Raleigh North Carolina 27607-6475 —
Not listed Winston-Salem North Carolina 27103 —
Not listed Dayton Ohio 45439 —
Not listed Toledo Ohio 43623 —
Not listed Oklahoma City Oklahoma 73112 —
Not listed Medford Oregon 97504 —
Not listed Portland Oregon 97210 —
Not listed Levittown Pennsylvania 19056-2404 —
Not listed Chattanooga Tennessee 37404 —
Not listed Austin Texas 78705 —
Not listed Beaumont Texas 77701 —
Not listed Colleyville Texas 76034 —
Not listed Dallas Texas 75230 —
Not listed Dallas Texas 75251 —
Not listed San Antonio Texas 78209 —
Not listed San Antonio Texas 78229 —
Not listed Alexandria Virginia 22304 —
Not listed Christiansburg Virginia 24073 —
Not listed Hampton Virginia 23666 —
Not listed Spokane Washington 99204 —
Not listed Spokane Washington 99208 —
Not listed Charleston West Virginia 25304-1965 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00529087, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 25, 2019 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00529087 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →