A Randomized Phase IIb Placebo-Controlled Study of R-ICE Chemotherapy With and Without SGN-40 for Patients With DLBCL
Public ClinicalTrials.gov record NCT00529503. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase IIb Placebo-controlled Study of R-ICE Chemotherapy With and Without SGN-40 (Anti-CD40 Humanized Monoclonal Antibody) for Second-line Treatment of Patients With Diffuse Large B-Cell Lymphoma (DLBCL)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized trial to estimate the activity of R-ICE plus SGN-40 vs. R-ICE plus placebo in patients with DLBCL. The study will assess safety and tolerability and will measure any additional clinical benefit observed in patients receiving SGN-40.
Study identification
- NCT ID
- NCT00529503
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 151 participants
Conditions and interventions
Interventions
- SGN-40 Drug
- placebo Drug
- rituximab Drug
- etoposide Drug
- carboplatin Drug
- ifosfamide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2007 (Type not available)
- Primary completion
- Dec 2009 (Actual)
- Completion
- May 2011 (Actual)
- Last update posted
- Feb 25, 2015
2007 – 2011
United States locations
- U.S. sites
- 24
- U.S. states
- 20
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294-3300 | — |
| University of California at Los Angeles | Los Angeles | California | 90095 | — |
| Stanford University Medical Center | Stanford | California | 94305-5821 | — |
| Christiana Care Health Systems | Newark | Delaware | 19718 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20007 | — |
| MD Anderson Cancer Center, Orlando | Orlando | Florida | 32806 | — |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Louisville - James Graham Brown Cancer Center | Louisville | Kentucky | 40202 | — |
| Sparrow Regional Cancer Center | Lansing | Michigan | 48912 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | — |
| Park Nicollet Institute | Saint Louis Park | Minnesota | 55416 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | — |
| St. Luke's Roosevelt Hospital Center | New York | New York | 10019 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Baylor Sammons Cancer Center | Dallas | Texas | 75246 | — |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030-4003 | — |
| MultiCare Health System | Tacoma | Washington | 98405 | — |
| West Virginia University | Morgantown | West Virginia | 26506-9162 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00529503, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 25, 2015 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00529503 live on ClinicalTrials.gov.