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Terminated Phase 2 Interventional

A Randomized Phase IIb Placebo-Controlled Study of R-ICE Chemotherapy With and Without SGN-40 for Patients With DLBCL

ClinicalTrials.gov ID: NCT00529503

Public ClinicalTrials.gov record NCT00529503. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:17 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Phase IIb Placebo-controlled Study of R-ICE Chemotherapy With and Without SGN-40 (Anti-CD40 Humanized Monoclonal Antibody) for Second-line Treatment of Patients With Diffuse Large B-Cell Lymphoma (DLBCL)

Study identification

NCT ID
NCT00529503
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Seagen Inc.
Industry
Enrollment
151 participants

Conditions and interventions

Interventions

  • SGN-40 Drug
  • placebo Drug
  • rituximab Drug
  • etoposide Drug
  • carboplatin Drug
  • ifosfamide Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2007
Primary completion
Nov 30, 2009
Completion
Apr 30, 2011
Last update posted
Feb 24, 2015

2007 – 2011

United States locations

U.S. sites
24
U.S. states
20
U.S. cities
24
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294-3300
University of California at Los Angeles Los Angeles California 90095
Stanford University Medical Center Stanford California 94305-5821
Christiana Care Health Systems Newark Delaware 19718
Georgetown University Washington D.C. District of Columbia 20007
MD Anderson Cancer Center, Orlando Orlando Florida 32806
Winship Cancer Institute, Emory University Atlanta Georgia 30322
Northwestern University Chicago Illinois 60611
University of Louisville - James Graham Brown Cancer Center Louisville Kentucky 40202
Sparrow Regional Cancer Center Lansing Michigan 48912
Mayo Clinic Rochester Rochester Minnesota 55905
Park Nicollet Institute Saint Louis Park Minnesota 55416
Washington University School of Medicine St Louis Missouri 63110
San Juan Oncology Associates Farmington New Mexico 87401
St. Luke's Roosevelt Hospital Center New York New York 10019
Cleveland Clinic Foundation Cleveland Ohio 44195
Ohio State University Columbus Ohio 43210
Providence Portland Medical Center Portland Oregon 97213
Medical University of South Carolina Charleston South Carolina 29425
Sarah Cannon Research Institute Nashville Tennessee 37203
Baylor Sammons Cancer Center Dallas Texas 75246
University of Texas MD Anderson Cancer Center Houston Texas 77030-4003
MultiCare Health System Tacoma Washington 98405
West Virginia University Morgantown West Virginia 26506-9162

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00529503, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 24, 2015 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00529503 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →