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Completed Phase 2 Interventional

A Study of C105 on Cognitive Dysfunction in Persons With Multiple Sclerosis

ClinicalTrials.gov ID: NCT00529581

Public ClinicalTrials.gov record NCT00529581. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 11:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Dose-Titration Study to Assess the Safety, Tolerability, and Efficacy of C105 in Persons With Multiple Sclerosis With Cognitive Impairment

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine the safety and efficacy of C105 in treating the cognitive deficits that can occur due to multiple sclerosis.

Study identification

NCT ID
NCT00529581
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Cognition Pharmaceuticals, LLC
Industry
Enrollment
150 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 2006 (Type not available)
Primary completion
Mar 2008 (Actual)
Completion
Apr 2008 (Actual)
Last update posted
May 28, 2008

2006 – 2008

United States locations

U.S. sites
30
U.S. states
16
U.S. cities
29
Facility City State ZIP Site status
Saint Joseph's Hospital, Barrow Neurology Clinics Phoenix Arizona 85013 —
Northwest Neuro Specialists, PLLC Tuscon Arizona 85741 —
Research Center for Clinical Studies West Lancaster California 93534 —
Loma Linda University, Department of Neurology Loma Linda California 92354 —
Associated Neurologists, P.C. Danbury Connecticut 06810 —
Associated Neurologist of Southern Connecticut, PC Fairfield Connecticut 06824 —
Yale University MS Center New Haven Connecticut 06510 —
Neurology Associates, PA Maitland Florida 32751 —
Lovelace Scientific Resources Sarasota Florida 34233 —
Roskamp Institute Sarasota Florida 34243 —
Suncoast Neuroscience Associates, Inc. St. Petersburg Florida 33701 —
Axiom Clinical Research of Florida Tampa Florida 33609 —
Shepard Center Atlanta Georgia 30309 —
University of Kansas Medical Center, Department of Neurology Kansas City Kansas 66160 —
MidAmerica Neuroscience Institute Lenexa Kansas 66214 —
University of Kentucky Lexington Kentucky 40536 —
Henry Ford Health System, Department of Neurology Detroit Michigan 48202 —
Northern Michigan Neurology Traverse City Michigan 49684 —
The Jacobs Neurological Institute Buffalo New York 14203 —
Raleigh Neurology Associates Raleigh North Carolina 17607 —
MeritCare Neuroscience Clinic Fargo North Dakota 58103 —
Neurology & Neuroscience Associates, Inc. Akron Ohio 44302 —
Riverhills Healthcare, Inc Cincinnati Ohio 45242 —
The Neurology Foundation, Inc. Providence Rhode Island 02905 —
Baylor College of Medicine Houston Texas 77030 —
Central Texas Neurology Round Rock Texas 78681 —
Integra Clinical Research San Antonio Texas 78229 —
University of Virginia, Department of Neurology Charlottesville Virginia 22908 —
Neurological Associates, Inc Richmond Virginia 23230 —
Capitol Neurology Charleston West Virginia 25301 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00529581, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 28, 2008 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00529581 live on ClinicalTrials.gov.

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