Comparison of Alemtuzumab and Rebif® Efficacy in Multiple Sclerosis, Study One
Public ClinicalTrials.gov record NCT00530348. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Rater-Blinded Study Comparing Two Annual Cycles of Intravenous Alemtuzumab to Three-Times Weekly Subcutaneous Interferon Beta-1a (Rebif®) in Treatment-Naïve Patients With Relapsing-Remitting Multiple Sclerosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was to establish the efficacy and safety of alemtuzumab (Lemtrada™) as a treatment for relapsing-remitting multiple sclerosis (MS), in comparison with subcutaneous (SC) interferon beta-1a (Rebif®). The study had enrolled participants who had not previously received MS disease-modifying therapies. Participants had monthly laboratory tests and comprehensive testing every 3 months.
Study identification
- NCT ID
- NCT00530348
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 581 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2007 (Type not available)
- Primary completion
- Apr 2011 (Actual)
- Completion
- Apr 2011 (Actual)
- Last update posted
- Nov 24, 2014
2007 – 2011
United States locations
- U.S. sites
- 36
- U.S. states
- 22
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| North Central Neurology Associates, P.C. | Cullman | Alabama | — | — |
| Barrow Neurological Institute, St. Joseph's Hospital & Medical Center | Phoenix | Arizona | — | — |
| Mayo Clinic Arizona | Scottsdale | Arizona | — | — |
| Northwest NeuroSpecialists, PLLC | Tucson | Arizona | — | — |
| Advanced Neurosciences Research | Fort Collins | Colorado | — | — |
| Neurological Associates | Pompano Beach | Florida | — | — |
| Axiom Clinical Research of Florida | Tampa | Florida | — | — |
| Idaho Falls Multiple Sclerosis Center, PLLC | Idaho Falls | Idaho | — | — |
| Consultants in Neurology, Ltd. | Northbrook | Illinois | — | — |
| Fort Wayne Neurological Center | Fort Wayne | Indiana | — | — |
| University of Kansas Medical Center | Kansas City | Kansas | — | — |
| MidAmerican Neuroscience Institute | Lenexa | Kansas | — | — |
| Associates in Neurology, PSC | Lexington | Kentucky | — | — |
| University of Louisville Research Foundation | Louisville | Kentucky | — | — |
| Louisiana State University Health Sciences Center | Shreveport | Louisiana | — | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | — | — |
| University of Michigan Health System | Ann Arbor | Michigan | — | — |
| Wayne State University | Detroit | Michigan | — | — |
| University of Nevada School of Medicine | Las Vegas | Nevada | — | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | — | — |
| University of New Mexico, Health Sciences Center, MS Specialty Clinic | Albuquerque | New Mexico | — | — |
| Empire Neurology | Latham | New York | — | — |
| Comprehensive Multiple Sclerosis Care Center at South Shore Neurologic Associates, P.C. | Patchogue | New York | — | — |
| University of Rochester Medical Center | Rochester | New York | — | — |
| Carolinas Medical Center (CMC), Neurosciences & Spine Institute (NSSI) | Charlotte | North Carolina | — | — |
| The Ohio State University Medical Center, Multiple Sclerosis Center | Columbus | Ohio | — | — |
| Oak Clinic for Multiple Sclerosis | Uniontown | Ohio | — | — |
| MS Center of Oklahoma | Oklahoma City | Oklahoma | — | — |
| Lehigh Valley Hospital Neurosciences and Pain Research | Allentown | Pennsylvania | — | — |
| Advanced Neurosciences Institute | Franklin | Tennessee | — | — |
| Biomedical Research Alliance of NY, LLC | Franklin | Tennessee | — | — |
| Hope Neurology PC | Knoxville | Tennessee | — | — |
| Baylor College of Medicine, Maxine Mesinger MS Clinic | Houston | Texas | — | — |
| Central Texas Neurology | Round Rock | Texas | — | — |
| Integra Clinical Research | San Antonio | Texas | — | — |
| Neurology Center of San Antonio | San Antonio | Texas | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 65 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00530348, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 24, 2014 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00530348 live on ClinicalTrials.gov.