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Terminated Phase 3 Interventional

A Phase 3 Study to Evaluate the Long-Term Safety of ThermoProfen™ in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee.

ClinicalTrials.gov ID: NCT00532038

Public ClinicalTrials.gov record NCT00532038. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 4:00 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label, Long-Term Safety Study to Evaluate the Safety of ThermoProfen™ for the Treatment of Mild to Moderate Pain Associated With Osteoarthritis of the Knee

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis. This study will evaluate the safety of long-term administration of ThermoProfen™ for the pain associated with osteoarthritis of the knee in adults. The study will be conducted in patients with pain associated with osteoarthritis and who have completed a previous efficacy study of ThermoProfen.

Study identification

NCT ID
NCT00532038
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
ZARS Pharma Inc.
Industry
Enrollment
179 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2007
Primary completion
Oct 31, 2008
Completion
Oct 31, 2008
Last update posted
Mar 15, 2012

2007 – 2008

United States locations

U.S. sites
20
U.S. states
14
U.S. cities
20
Facility City State ZIP Site status
Not listed Anaheim California 92801
Not listed San Diego California 92103
Not listed Westlake Village California 91361
Not listed Clearwater Florida 33761
Not listed Pembroke Pines Florida 33024
Not listed Springfield Illinois 62704
Not listed Evansville Indiana 47714
Not listed Overland Park Kansas 66215
Not listed Baltimore Maryland 21239
Not listed Wheaton Maryland 20902
Not listed Kansas City Missouri 64114
Not listed Mercerville New Jersey
Not listed Raleigh North Carolina 27612
Not listed Lake Oswego Oregon 97035
Not listed Duncansville Pennsylvania 16635
Not listed Erie Pennsylvania 16508
Not listed Anderson South Carolina 29621
Not listed Nashville Tennessee 37205
Not listed Houston Texas 77090
Not listed San Antonio Texas 78217

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Recently updated Osteoarthritis trials

Other public records listing Osteoarthritis. Sorted by last update posted; newest first. Not a recommendation.

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About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00532038, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 15, 2012 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00532038 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →