A Study of the Safety and Efficacy of Two Doses of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects
Public ClinicalTrials.gov record NCT00532779. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double Blind, Placebo Controlled Study Comparing the Safety and Efficacy of Two Doses of Naltrexone Sustained Release (SR)/Bupropion Sustained Release (SR) and Placebo in Obese Subjects
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether 2 doses of the combination of naltrexone SR and bupropion SR are safe and effective in the treatment of obesity.
Study identification
- NCT ID
- NCT00532779
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,742 participants
Conditions and interventions
Conditions
Interventions
- Naltrexone SR 16 mg/Bupropion SR 360 mg /day Drug
- Naltrexone SR 32 mg/Bupropion SR 360 mg /day Drug
- Placebo Drug
- Ancillary therapy Behavioral
Drug · Behavioral
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2007 (Type not available)
- Primary completion
- May 2009 (Actual)
- Completion
- May 2009 (Actual)
- Last update posted
- Nov 21, 2014
2007 – 2009
United States locations
- U.S. sites
- 34
- U.S. states
- 20
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Radiant Research | Birmingham | Alabama | 35209 | — |
| SelfCenter, PC | Fairhope | Alabama | 36532 | — |
| Radiant Research, Phoenix Southeast | Chandler | Arizona | 85225 | — |
| Advanced Clinical Research Institute | Anaheim | California | 92801 | — |
| Advance Clinical Research Institute | Orange | California | 92869 | — |
| Scripps Clinic Del Mar | San Diego | California | 92130 | — |
| VA San Diego Healthcare System | San Diego | California | 92161 | — |
| Miami Research Associates | Miami | Florida | 33143 | — |
| University Clinical Research | Pembroke Pines | Florida | 33024 | — |
| Georgia Clinical Research | Atlanta | Georgia | 30308 | — |
| CSRA Partners in Health, Inc | Augusta | Georgia | 30909 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Radiant Research | Chicago | Illinois | 60610 | — |
| Welborn Clinic | Evansville | Indiana | 47713 | — |
| Radiant Research Kansas City | Overland Park | Kansas | 66202 | — |
| Central Kentucky Research Associates, Inc. | Lexington | Kentucky | 40509 | — |
| Pennington Biomedical Research Center | Baton Rouge | Louisiana | 70808 | — |
| Medical Research Institute | Slidell | Louisiana | 70458 | — |
| Health Trends Research, LLC | Baltimore | Maryland | 21209 | — |
| FutureCare Studies | Springfield | Massachusetts | 01103 | — |
| Center for Nutrition and Metabolic Disorders | Reno | Nevada | 89557 | — |
| Center for Nutrition and Preventive Medicine | Charlotte | North Carolina | 28211 | — |
| Wake Research Associates, LLC | Raleigh | North Carolina | 27612 | — |
| Rapid Medical Research, Inc. | Cleveland | Ohio | 44122 | — |
| Central Ohio Nutrition Center, Inc. | Columbus | Ohio | 43213 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Summit Research Network (Oregon), Inc. | Portland | Oregon | 97210 | — |
| Internal Medicine Associates of Cordova | Cordova | Tennessee | 38018 | — |
| Jackson Clinic, PA | Jackson | Tennessee | 38305 | — |
| Covance Clinical Research Unit Austin | Austin | Texas | 78752 | — |
| Radiant Research | Dallas | Texas | 75231 | — |
| Baylor Endocrine Center | Dallas | Texas | 75246 | — |
| Radiant Research | San Antonio | Texas | 78217 | — |
| Oakwell Clinical Research | San Antonio | Texas | 78218 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00532779, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 21, 2014 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00532779 live on ClinicalTrials.gov.