Hydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell Disease
Public ClinicalTrials.gov record NCT00532883. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Effectiveness of Hydroxyurea and Magnesium Pidolate Alone and in Combination in Hemoglobin SC Disease: A Phase II Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Sickle cell disease (SCD), also known as sickle cell anemia, is an inherited blood disease that can cause intense pain episodes. Hemoglobin SCD (HbSC) is a form of SCD that is characterized by dense red blood cells. The purpose of this study is to evaluate the safety and effectiveness of hydroxyurea and magnesium pidolate, alone and combined, at reducing red blood cell density and the frequency of pain episodes in people with HbSC.
Study identification
- NCT ID
- NCT00532883
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 44 participants
Conditions and interventions
Conditions
Interventions
- Hydroxyurea Drug
- Magnesium Pidolate Drug
- Placebo Pills and Placebo Liquid Other
Drug · Other
Eligibility (public fields only)
- Age range
- 5 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2007 (Type not available)
- Primary completion
- Mar 2009 (Actual)
- Completion
- Aug 2009 (Actual)
- Last update posted
- Jan 18, 2013
2007 – 2009
United States locations
- U.S. sites
- 19
- U.S. states
- 16
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Children's Hospital and Research Center | Oakland | California | 94609-1809 | — |
| University of California Davis | Sacramento | California | 95817 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Children's Healthcare of Atlanta | Atlanta | Georgia | 30342-1600 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Children's Hospital Boston | Boston | Massachusetts | 02118 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Montefiore Medical Center | The Bronx | New York | 10463 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Cincinnati Children's Hospital | Cincinnati | Ohio | 45229 | — |
| University of Oklahoma | Oklahoma City | Oklahoma | 73104 | — |
| Saint Christopher's Hospital | Philadelphia | Pennsylvania | 19134-1095 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19444 | — |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | — |
| Children's Medical Center | Dallas | Texas | 75235 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00532883, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 18, 2013 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00532883 live on ClinicalTrials.gov.