A Study of the Effect of Tocilizumab on Markers of Atherogenic Risk in Patients With Moderate to Severe Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT00535782. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Mechanism of Action Study to Evaluate the Effects of IL-6 Receptor Blockade With Tocilizumab (TCZ) on Lipids, Arterial Stiffness, and Markers of Atherogenic Risk in Patients With Moderate to Severe Active Rheumatoid Arthritis (RA).
Study identification
- NCT ID
- NCT00535782
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 132 participants
Conditions and interventions
Conditions
Interventions
- Tocilizumab Drug
- Placebo Drug
- Methotrexate Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 30, 2007
- Primary completion
- Sep 29, 2008
- Completion
- Jan 30, 2011
- Last update posted
- Jul 25, 2017
2007 – 2011
United States locations
- U.S. sites
- 26
- U.S. states
- 16
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group; Llc, Central | Anniston | Alabama | 36207 | — |
| Rheumatology Associates of North Alabama | Huntsville | Alabama | 35801 | — |
| Advanced Arthritis Care & Research | Scottsdale | Arizona | 85258 | — |
| Catalina Pointe Clinical Research, Inc. | Tucson | Arizona | 85704 | — |
| Pacific Arthritis Care Center | Los Angeles | California | 90045 | — |
| Arthritis & Rheumatism; Disease Specialities | Aventura | Florida | 33180 | — |
| Science and Research Institute, Inc. | Jupiter | Florida | 33458 | — |
| Arthritis Center Palm Harbor | Palm Harbor | Florida | 34684 | — |
| Arthritis Rsrch of Florida, Inc. | Palm Harbor | Florida | 34684 | — |
| Sarasota Arthritis Center; Research Dept | Sarasota | Florida | 34239 | — |
| Burnette & Silverfield, MDS | Tampa | Florida | 33614 | — |
| Arthritis & Rheumatology of Georgia | Atlanta | Georgia | 30342 | — |
| Deerbrook Medical Associates | Vernon Hills | Illinois | 60061 | — |
| Johns Hopkins Uni | Baltimore | Maryland | 21224 | — |
| Borgess Research Institute | Kalamazoo | Michigan | 49048 | — |
| Jackson Arthritis Clinic | Flowood | Mississippi | 39232 | — |
| Physicians Group, LC DBA Rheumatology & Internal Medicine Associates | St Louis | Missouri | 63131 | — |
| NJP Clinical Research | Clifton | New Jersey | 07012 | — |
| Asheville Arthritis & Osteoporosis Center, PA | Asheville | North Carolina | 28803 | — |
| Health Research of Oklahoma, Llc | Oklahoma City | Oklahoma | 73103 | — |
| Lehigh Valley Hospital; Dept of Medicine | Allentown | Pennsylvania | 18103 | — |
| Altoona Center For Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Clinical Research Center of Reading | Wyomissing | Pennsylvania | 19610 | — |
| Houston Inst. For Clinical Research | Houston | Texas | 77074 | — |
| Texas Research Center | Sugar Land | Texas | 77479 | — |
| South Puget Sound Clinical Research | Olympia | Washington | 98502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00535782, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 25, 2017 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00535782 live on ClinicalTrials.gov.