Optimizing Treatment for Treatment-Experienced, HIV-Infected People
Public ClinicalTrials.gov record NCT00537394. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The Optimized Treatment That Includes or Omits NRTIs Trial: A Randomized Strategy Study for HIV-1-Infected Treatment-Experienced Subjects Using the cPSS to Select an Effective Regimen
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of anti-HIV therapy is to prevent HIV from replicating. Long-term control of HIV requires at least two anti-HIV drugs that are active against the virus. Drug resistance is a problem for many treatment-experienced, HIV-infected people. The purpose of this study was to determine the benefit of adding a nucleoside reverse transcriptase inhibitor (NRTI) to a new anti-HIV drug regimen for the suppression of HIV.
Study identification
- NCT ID
- NCT00537394
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 517 participants
Conditions and interventions
Conditions
Interventions
- Enfuvirtide Drug
- Raltegravir Drug
- Darunavir Drug
- Tipranavir Drug
- Etravirine Drug
- Maraviroc Drug
Drug
Eligibility (public fields only)
- Age range
- 16 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2008 (Type not available)
- Primary completion
- May 2012 (Actual)
- Completion
- Apr 2013 (Actual)
- Last update posted
- Nov 4, 2021
2008 – 2013
United States locations
- U.S. sites
- 61
- U.S. states
- 23
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Therapeutics CRS | Birmingham | Alabama | 35294-2050 | — |
| Miller Children's Hosp. Long Beach CA NICHD CRS | Long Beach | California | 90806 | — |
| University of Southern California CRS | Los Angeles | California | 90033 | — |
| Usc La Nichd Crs | Los Angeles | California | 90033 | — |
| UCLA CARE Center CRS | Los Angeles | California | 90035 | — |
| UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CRS | Los Angeles | California | 90095-1752 | — |
| Stanford AIDS Clinical Trials Unit CRS | Palo Alto | California | 94304-5350 | — |
| UCSD Antiviral Research Center CRS | San Diego | California | 92103 | — |
| Ucsf Hiv/Aids Crs | San Francisco | California | 94110 | — |
| Univ. of California San Francisco NICHD CRS | San Francisco | California | 94143 | — |
| University of Colorado Hospital CRS | Aurora | Colorado | 80045 | — |
| Denver Public Health CRS | Denver | Colorado | 80204 | — |
| Georgetown University CRS (GU CRS) | Washington D.C. | District of Columbia | 20007 | — |
| Children's National Med. Ctr. ATN CRS | Washington D.C. | District of Columbia | 20010 | — |
| Howard Univ. Washington DC NICHD CRS | Washington D.C. | District of Columbia | 20060 | — |
| Pediatric Perinatal HIV Clinical Trials Unit CRS | Miami | Florida | 33136 | — |
| The Ponce de Leon Center CRS | Atlanta | Georgia | 30308-2012 | — |
| Northwestern University CRS | Chicago | Illinois | 60611 | — |
| Rush University CRS | Chicago | Illinois | 60612 | — |
| Tulane Univ. New Orleans NICHD CRS | New Orleans | Louisiana | 70112-2699 | — |
| IHV Baltimore Treatment CRS | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University CRS | Baltimore | Maryland | 21205 | — |
| Massachusetts General Hospital CRS (MGH CRS) | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital Therapeutics Clinical Research Site (BWH TCRS) CRS | Boston | Massachusetts | 02115 | — |
| Bmc Actg Crs | Boston | Massachusetts | 02118 | — |
| Boston Medical Center Ped. HIV Program NICHD CRS | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconess Med. Ctr., ACTG CRS | Boston | Massachusetts | 02215 | — |
| Wayne State Univ. CRS | Detroit | Michigan | 48201 | — |
| Henry Ford Hosp. CRS | Detroit | Michigan | 48202 | — |
| Washington University Therapeutics (WT) CRS | St Louis | Missouri | 63110 | — |
| Cooper Univ. Hosp. CRS | Camden | New Jersey | 08103 | — |
| New Jersey Medical School Clinical Research Center CRS | Newark | New Jersey | 07103 | — |
| Rutgers - New Jersey Medical School CRS | Newark | New Jersey | 07103 | — |
| Weill Cornell Chelsea CRS | New York | New York | 10011 | — |
| NY Univ. HIV/AIDS CRS | New York | New York | 10016 | — |
| Nyu Ny Nichd Crs | New York | New York | 10016 | — |
| Metropolitan Hosp. NICHD CRS | New York | New York | 10029 | — |
| Columbia P&S CRS | New York | New York | 10032-3732 | — |
| Columbia IMPAACT CRS | New York | New York | 10032 | — |
| Harlem ACTG CRS | New York | New York | 10037 | — |
| Trillium Health ACTG CRS | Rochester | New York | 14607 | — |
| Univ. of Rochester ACTG CRS | Rochester | New York | 14642 | — |
| Bronx-Lebanon Hosp. Ctr. CRS | The Bronx | New York | 10457 | — |
| Chapel Hill CRS | Chapel Hill | North Carolina | 27514 | — |
| Duke Univ. Med. Ctr. Adult CRS | Durham | North Carolina | 27710 | — |
| Cincinnati CRS | Cincinnati | Ohio | 45267-0405 | — |
| Case Clinical Research Site | Cleveland | Ohio | 44106 | — |
| MetroHealth CRS | Cleveland | Ohio | 44109 | — |
| Ohio State University CRS | Columbus | Ohio | 43210 | — |
| The Research & Education Group-Portland CRS | Portland | Oregon | 97210 | — |
| Penn Therapeutics, CRS | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson Univ. Med. Ctr. CRS | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh CRS | Pittsburgh | Pennsylvania | 15213-2582 | — |
| The Miriam Hospital Clinical Research Site (TMH CRS) CRS | Providence | Rhode Island | 02906 | — |
| St. Jude Children's Research Hospital CRS | Memphis | Tennessee | 38105 | — |
| Vanderbilt Therapeutics (VT) CRS | Nashville | Tennessee | 37204 | — |
| Trinity Health and Wellness Center CRS | Dallas | Texas | 75208 | — |
| Houston AIDS Research Team CRS | Houston | Texas | 77030 | — |
| Texas Children's Hospital CRS | Houston | Texas | 77030 | — |
| Virginia Commonwealth Univ. Medical Ctr. CRS | Richmond | Virginia | 23298 | — |
| University of Washington AIDS CRS | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00537394, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 4, 2021 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00537394 live on ClinicalTrials.gov.