Study Evaluating the Efficacy and Safety of Topical Diclofenac Spray in Osteoarthritis of the Knee: Trial II
Public ClinicalTrials.gov record NCT00546832. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The Efficacy and Safety of TDS-943 in the Treatment of Osteoarthritis of the Knee: Pivotal Study II
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to evaluate the efficacy and safety of TDS-943 (topical diclofenac spray) compared to oral celecoxib and placebo in subjects with osteoarthritis of the knee. The main hypotheses are that TDS-943 will be better than placebo and no worse than celecoxib.
Study identification
- NCT ID
- NCT00546832
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 650 participants
Conditions and interventions
Conditions
Interventions
- TDS-943 (topical diclofenac sodium 4% spray) Drug
- celecoxib Drug
- placebo Other
Drug · Other
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2007
- Primary completion
- Sep 30, 2008
- Completion
- Oct 31, 2008
- Last update posted
- Oct 12, 2010
2007 – 2008
United States locations
- U.S. sites
- 49
- U.S. states
- 26
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | 35209 | — |
| Not listed | Birmingham | Alabama | 35244 | — |
| Not listed | Chandler | Arizona | 85225 | — |
| Not listed | Phoenix | Arizona | 85032 | — |
| Not listed | Little Rock | Arkansas | 72205 | — |
| Not listed | Anaheim | California | 92801 | — |
| Not listed | Anaheim | California | 92804 | — |
| Not listed | Foothill Ranch | California | 92610 | — |
| Not listed | Irvine | California | 92618 | — |
| Not listed | Westlake Village | California | 91361 | — |
| Not listed | Denver | Colorado | 80209 | — |
| Not listed | Danbury | Connecticut | 06810 | — |
| Not listed | Milford | Connecticut | 06460 | — |
| Not listed | Stanford | Connecticut | 06905 | — |
| Not listed | Boynton Beach | Florida | 33472 | — |
| Not listed | Delray Beach | Florida | 33484 | — |
| Not listed | New Smyrna Beach | Florida | 32168 | — |
| Not listed | Ococee | Florida | 34761 | — |
| Not listed | Sarasota | Florida | 34239 | — |
| Not listed | St. Petersburg | Florida | 33702 | — |
| Not listed | Blue Ridge | Georgia | 30513 | — |
| Not listed | Marietta | Georgia | 30066 | — |
| Not listed | Savannah | Georgia | 31406 | — |
| Not listed | Boise | Idaho | 83702 | — |
| Not listed | Chicago | Illinois | 60611 | — |
| Not listed | Overland Park | Kansas | 66202 | — |
| Not listed | Towson | Maryland | 21286 | — |
| Not listed | Brockton | Massachusetts | 02301 | — |
| Not listed | Kalamazoo | Michigan | 49009 | — |
| Not listed | Kansas City | Missouri | 64114 | — |
| Not listed | Omaha | Nebraska | 68144 | — |
| Not listed | Berlin | New Jersey | 08009 | — |
| Not listed | Medford | New Jersey | 08055 | — |
| Not listed | Brooklyn | New York | 11214 | — |
| Not listed | Asheville | North Carolina | 28801 | — |
| Not listed | Cincinnati | Ohio | 45246 | — |
| Not listed | Cleveland | Ohio | 44121 | — |
| Not listed | Marion | Ohio | 43302 | — |
| Not listed | Oklahoma City | Oklahoma | 73103 | — |
| Not listed | Oklahoma City | Oklahoma | 73112 | — |
| Not listed | Bensalem | Pennsylvania | 19020 | — |
| Not listed | Duncansville | Pennsylvania | 16635 | — |
| Not listed | Charleston | South Carolina | 29406 | — |
| Not listed | Austin | Texas | 78704 | — |
| Not listed | Nederland | Texas | 77627 | — |
| Not listed | San Antonio | Texas | 78209 | — |
| Not listed | San Antonio | Texas | 78229 | — |
| Not listed | Virginia Beach | Virginia | 23455 | — |
| Not listed | Milwaukee | Wisconsin | 53209 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00546832, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 12, 2010 · Synced Sep 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00546832 live on ClinicalTrials.gov.