Effects of Titrated Oral Tolvaptan 15-60 mg Once Daily (QD) on Cognitive and Neurological Function in Elderly Hyponatremic Patients
Public ClinicalTrials.gov record NCT00550459. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Pilot, Phase 3B, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Study of the Effects of Titrated Oral Tolvaptan 15, 30, or 60 mg QD on Cognitive and Neurological Function in Elderly Hyponatremic Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Demonstrate an improvement in the composite scores of validated neurocognitive tests in elderly subjects with chronic sub-clinical (i.e., asymptomatic) hyponatremia.
Study identification
- NCT ID
- NCT00550459
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 57 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2007
- Primary completion
- Jan 31, 2009
- Completion
- Feb 28, 2009
- Last update posted
- Apr 27, 2011
2007 – 2009
United States locations
- U.S. sites
- 12
- U.S. states
- 10
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sarah. S. Olelewe, MD | Hawthorne | California | 90250 | — |
| Progressive Clinical Research | Vista | California | 92083 | — |
| Pikes Peak Cardiology | Colorado Springs | Colorado | 80907 | — |
| Innovative Research of West FL | Largo | Florida | 33770 | — |
| Coastal Nephrology Assoc. Research Center | Punta Gorda | Florida | 33950 | — |
| Rockdale Medical Research Associates | Conyers | Georgia | 30094 | — |
| Otis Barnum, DO | Natchitoches | Louisiana | 71457 | — |
| Lillestol Research, LLC | Fargo | North Dakota | 58106 | — |
| Carolina Research Associates | Columbia | South Carolina | 29201 | — |
| Wayne O. Wells, MD | Lebanon | Tennessee | 37087 | — |
| Memorial Clinical Associates | Houston | Texas | 77043 | — |
| Mitchell Rosner, MD | Charlottesville | Virginia | 22908 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00550459, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2011 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00550459 live on ClinicalTrials.gov.