Methotrexate-Inadequate Response Study
Open the official record
This page only displays public information reproduced from the official ClinicalTrials.gov record NCT00559585. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IIIB Multicenter, Randomized, Double-Blind, Double-Dummy Study to Compare the Efficacy and Safety of Abatacept Administered Subcutaneously and Intravenously in Subjects With Rheumatoid Arthritis, Receiving Background Methotrexate, and Experiencing an Inadequate Response to Methotrexate
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether a weekly subcutaneous dose of abatacept yields clinical efficacy comparable to that of monthly intravenous doses of abatacept in participants with rheumatoid arthritis and an inadequate response to current methotrexate therapy.
Study identification
- NCT ID
- NCT00559585
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,492 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2008 (Type not available)
- Primary completion
- Nov 2009 (Actual)
- Completion
- Sep 2014 (Actual)
- Last update posted
- Nov 9, 2015
2008 – 2014
United States locations
- U.S. sites
- 70
- U.S. states
- 30
- U.S. cities
- 66
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Rheumatology Associates, Pc | Birmingham | Alabama | 35205 | — |
| Coastal Clinical Research, Inc | Mobile | Alabama | 36608 | — |
| Advanced Arthritis Care & Research | Scottsdale | Arizona | 85258 | — |
| Catalina Pointe Clinical Research, Inc. | Tucson | Arizona | 85704 | — |
| St. Joseph'S Mercy Clinic | Hot Springs | Arkansas | 71913 | — |
| Talbert Medical Group | Huntington Beach | California | 92646 | — |
| Allergy & Rheumatology Medical Clinic, Inc. | La Jolla | California | 92037 | — |
| Valerius Medical Group &Research Ctr. Of Greater Long Beach | Long Beach | California | 90806 | — |
| Stanford University School Of Medicine | Palo Alto | California | 94304 | — |
| San Diego Arthritis Medical Clinic | San Diego | California | 92108 | — |
| Boulder Medical Center | Boulder | Colorado | 80304 | — |
| Arthritis Assoc And Osteo Ctr Of Col Sprgs | Colorado Springs | Colorado | 80910 | — |
| Denver Arthritis Clinic | Denver | Colorado | 80230 | — |
| Arthritis Center Of The Rockies, Pc | Loveland | Colorado | 80538 | — |
| Guadagnoli, Germano | Bridgeport | Connecticut | 06606 | — |
| Joao Nascimento | Bridgeport | Connecticut | 06606 | — |
| Clinical Research Center Of Ct/Ny | Danbury | Connecticut | 06810 | — |
| Arthritis And Rheumatic Disease Specialties | Aventura | Florida | 33180 | — |
| Arthritis & Osteoporosis Treatment Center, Pa | Orange Park | Florida | 32073 | — |
| Rheumatology Associates Of Central Florida | Orlando | Florida | 32806 | — |
| The Arthritis Center | Palm Harbor | Florida | 34684 | — |
| Sarasota Arthritis Research Center | Sarasota | Florida | 34239 | — |
| Arthritis & Rheumatology Of Georgia,Pc | Atlanta | Georgia | 30342 | — |
| Boise Rheumatology/ Intermountain Research Center, Inc | Boise | Idaho | 83702 | — |
| Coeur D'Alene Arthrit Clin | Coeur d'Alene | Idaho | 83814 | — |
| Quincy Medical Group | Quincy | Illinois | 62301 | — |
| Rockford Orthopedic Associates, Ltd. | Rockford | Illinois | 61107 | — |
| The Arthritis Center | Springfield | Illinois | 62704 | — |
| Klein And Associates, M.D., Pa | Cumberland | Maryland | 21502 | — |
| Clinical Pharmacology Study Group | Worcester | Massachusetts | 01610 | — |
| Shores Rheumatology, P. C. | Saint Clair Shores | Michigan | 48081 | — |
| Arthritis Assoicates Of Mississippi | Jackson | Mississippi | 39202 | — |
| Kansas City Internal Medicine | Lee's Summit | Missouri | 64086 | — |
| Physician Research Collaboration, Llc | Lincoln | Nebraska | 68516 | — |
| Allergy And Arthritis Associates | Dover | New Jersey | 07801 | — |
| Albuquerque Clinical Trials, Inc. | Albuquerque | New Mexico | 87102 | — |
| Albuquerque Rehabilitation & Rheumatology Pc | Albuquerque | New Mexico | 87102 | — |
| The Center For Rheumatology, Llp | Albany | New York | 12206 | — |
| Southern Tier Arthritis & Rheumatism | Olean | New York | 14760 | — |
| Arthritis Health Associates | Syracuse | New York | 13210 | — |
| Asheville Rheumatology & Osteoporosis Research Asso P. A. | Asheville | North Carolina | 28801 | — |
| The Arthritis Clinic & Carolina Bone & Joint | Charlotte | North Carolina | 28210 | — |
| Rheumatology | Durham | North Carolina | 27704 | — |
| Physicians East, Pa | Greenville | North Carolina | 27834 | — |
| Carolina Pharmaceutical Research | Statesville | North Carolina | 28625 | — |
| Carolina Arthritis Associates | Wilmington | North Carolina | 28401 | — |
| Cincinnati Rheumatic Disease Study Group | Cincinnati | Ohio | 45219 | — |
| Health Research Of Oklahoma | Oklahoma City | Oklahoma | 73103 | — |
| Oklahoma Center For Arthritis Therapy And Research | Tulsa | Oklahoma | 74104 | — |
| Healthcare Research Consultants | Tulsa | Oklahoma | 74135 | — |
| Pro Research | Eugene | Oregon | 97401 | — |
| Portland Rheumatology Clinic, Llc | Lake Oswego | Oregon | 97035 | — |
| East Penn Rheumatology Associates | Bethlehem | Pennsylvania | 18015 | — |
| Rheumatology Associates | Providence | Rhode Island | 02906 | — |
| Low Country Rheumatology, Pa | Charleston | South Carolina | 29406 | — |
| Columbia Arthritis Center | Columbia | South Carolina | 29204 | — |
| Carolina Health Specialists | Myrtle Beach | South Carolina | 29572 | — |
| Acme Research, Llc | Orangeburg | South Carolina | 29118 | — |
| Arthritis Clinic | Jackson | Tennessee | 38305 | — |
| Rheumatology Consultants Pllc | Knoxville | Tennessee | 37909 | — |
| The Arthritis Group, Pc | Memphis | Tennessee | 38104 | — |
| St. Thomas Hospital Tower East | Nashville | Tennessee | 37205 | — |
| Walter F. Chase | Austin | Texas | 78705 | — |
| Rheumatic Disease Clinical Research Center, Llc | Houston | Texas | 77004 | — |
| Accurate Clinical Research | Houston | Texas | 77034 | — |
| Texas Research Center | Sugarland | Texas | 77479 | — |
| Arthritis Clinic Of Northern Virginia, P.C. | Arlington | Virginia | 22205 | — |
| Center For Arthritis & Rheumatic Diseases, Pc | Chesapeake | Virginia | 23320 | — |
| South Puget Sound Clinincal Research Center | Olympia | Washington | 98502 | — |
| Tacoma Center For Arthritis Research Ps | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 133 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00559585, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 9, 2015 · Synced Nov 15, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.