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Completed Phase 3 Interventional Results available

VERxVE Study on Efficacy and Safety of Nevirapine XR in Comparison to Nevirapine IR With Truvada in Naive HIV+ Patients

ClinicalTrials.gov ID: NCT00561925

Public ClinicalTrials.gov record NCT00561925. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 13, 2026, 12:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomised, Double Blind, Double Dummy, Parallel Group, Active Controlled Trial to Evaluate the Antiviral Efficacy of 400 mg QD neVirapine Extended Release Formulation in Comparison to 200 mg BID neVirapinE Immediate Release in Combination With Truvada® in Antiretroviral Therapy naïve HIV-1 Infected Patients (VERxVE)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective of this study is to evaluate the efficacy of 400 mg QD nevirapine extended release (NVP XR) formulation versus 200 mg BID nevirapine immediate release (NVP IR) in ARV therapy naïve HIV-1 infected patients after 48 weeks of treatment. Secondary objectives are to evaluate safety and pharmacokinetics of NVP XR and NVP IR.

Study identification

NCT ID
NCT00561925
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Boehringer Ingelheim
Industry
Enrollment
1,068 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2007
Primary completion
Oct 31, 2011
Completion
Not listed
Last update posted
Apr 6, 2014

Started 2007

United States locations

U.S. sites
41
U.S. states
15
U.S. cities
33
Facility City State ZIP Site status
1100.1486.0040 Boehringer Ingelheim Investigational Site Birmingham Alabama
1100.1486.0013 Boehringer Ingelheim Investigational Site Phoenix Arizona
1100.1486.0017 Boehringer Ingelheim Investigational Site Bakersfield California
1100.1486.0001 Boehringer Ingelheim Investigational Site Beverly Hills California
1100.1486.0057 Boehringer Ingelheim Investigational Site Beverly Hills California
1100.1486.0059 Boehringer Ingelheim Investigational Site Beverly Hills California
1100.1486.0035 Boehringer Ingelheim Investigational Site Long Beach California
1100.1486.0025 Boehringer Ingelheim Investigational Site Los Angeles California
1100.1486.0034 Boehringer Ingelheim Investigational Site Los Angeles California
1100.1486.0041 Boehringer Ingelheim Investigational Site Los Angeles California
1100.1486.0032 Boehringer Ingelheim Investigational Site Sacramento California
1100.1486.0028 Boehringer Ingelheim Investigational Site San Diego California
1100.1486.0023 Boehringer Ingelheim Investigational Site Washington D.C. District of Columbia
1100.1486.0029 Boehringer Ingelheim Investigational Site Washington D.C. District of Columbia
1100.1486.0048 Boehringer Ingelheim Investigational Site Washington D.C. District of Columbia
1100.1486.0037 Boehringer Ingelheim Investigational Site Clearwater Florida
1100.1486.0043 Boehringer Ingelheim Investigational Site Fort Lauderdale Florida
1100.1486.0012 Boehringer Ingelheim Investigational Site Miami Florida
1100.1486.0007 Boehringer Ingelheim Investigational Site Miami Beach Florida
1100.1486.0039 Boehringer Ingelheim Investigational Site Orlando Florida
1100.1486.0050 Boehringer Ingelheim Investigational Site Vero Beach Florida
1100.1486.0014 Boehringer Ingelheim Investigational Site Wilton Manors Florida
1100.1486.0031 Boehringer Ingelheim Investigational Site Atlanta Georgia
1100.1486.0010 Boehringer Ingelheim Investigational Site Macon Georgia
1100.1486.0053 Boehringer Ingelheim Investigational Site Boise Idaho
1100.1486.0002 Boehringer Ingelheim Investigational Site Chicago Illinois
1100.1486.0026 Boehringer Ingelheim Investigational Site Chicago Illinois
1100.1486.0020 Boehringer Ingelheim Investigational Site Lexington Kentucky
1100.1486.0019 Boehringer Ingelheim Investigational Site Berkley Michigan
1100.1486.0006 Boehringer Ingelheim Investigational Site Kansas City Missouri
1100.1486.0027 Boehringer Ingelheim Investigational Site St Louis Missouri
1100.1486.0055 Boehringer Ingelheim Investigational Site Charlotte North Carolina
1100.1486.0003 Boehringer Ingelheim Investigational Site Huntersville North Carolina
1100.1486.0005 Boehringer Ingelheim Investigational Site Akron Ohio
1100.1486.0004 Boehringer Ingelheim Investigational Site Austin Texas
1100.1486.0018 Boehringer Ingelheim Investigational Site Dallas Texas
1100.1486.0038 Boehringer Ingelheim Investigational Site Dallas Texas
1100.1486.0044 Boehringer Ingelheim Investigational Site Fort Worth Texas
1100.1486.0054 Boehringer Ingelheim Investigational Site Harlingen Texas
1100.1486.0009 Boehringer Ingelheim Investigational Site Houston Texas
1100.1486.0046 Boehringer Ingelheim Investigational Site Annandale Virginia

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 161 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00561925, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 6, 2014 · Synced Sep 13, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00561925 live on ClinicalTrials.gov.

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