ClinicalTrials.gov record
A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee
ClinicalTrials.gov ID: NCT00565812
Public ClinicalTrials.gov record NCT00565812. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Long-Term, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Radiographic Study To Investigate The Safety And Efficacy Of Orally Administered SD-6010 In Subjects With Symptomatic Osteoarthritis Of The Knee
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this 2-year study is to evaluate the safety, tolerability and disease modifying efficacy of SD 6010, an inhibitor of inducible nitric oxide synthase (iNOS), in overweight and obese subjects with knee osteoarthritis. The efficacy of SD-6010 will be evaluated by radiography using joint space narrowing in the medial tibiofemoral compartment of the study knee as the primary endpoint.
Study identification
- NCT ID
- NCT00565812
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 1,457 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2007 (Type not available)
- Primary completion
- Oct 2011 (Actual)
- Completion
- Nov 2011 (Actual)
- Last update posted
- Dec 30, 2016
2007 – 2011
United States locations
- U.S. sites
- 120
- U.S. states
- 34
- U.S. cities
- 86
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Brookwood Internists, P.C. | Birmingham | Alabama | 35209 | — |
| Greystone Medical Center | Birmingham | Alabama | 35242 | — |
| Pivotal Research Centers | Peoria | Arizona | 85381 | — |
| Arizona Research Center | Phoenix | Arizona | 85023 | — |
| Pivotal Research Centers | Phoenix | Arizona | 85027 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| Martin Bowen Hefley Orthopedics | Little Rock | Arkansas | 72205 | — |
| Teton Research, LLC | Little Rock | Arkansas | 72205 | — |
| Med Center | Carmichael | California | 95608 | — |
| College Hospital Costa Mesa | Costa Mesa | California | 92627 | — |
| NeuroNetwork Trials | Costa Mesa | California | 92627 | — |
| Med Investigations, Inc. | Fair Oaks | California | 95628 | — |
| Sierra Clinical Research | Roseville | California | 95661 | — |
| University of California Davis Health System | Sacramento | California | 95817 | — |
| University of California Davis | Sacramento | California | 95817 | — |
| Scripps Clinic-Clinical Research | San Diego | California | 92128 | — |
| Plaza Medical Imaging | Santa Ana | California | 92704 | — |
| Denver Internal Medicine Group | Denver | Colorado | 80209 | — |
| Mountain View Clinical Research, Inc. | Denver | Colorado | 80209 | — |
| New West Physicians Clinical Research | Golden | Colorado | 80401 | — |
| Advanced Radiology Consultants | Fairfield | Connecticut | 06824 | — |
| Advanced Radiology Consultants | Stamford | Connecticut | 06902 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| New England Research Associates, LLC | Trumbull | Connecticut | 06611 | — |
| Southeastern Arthritis Center | Gainesville | Florida | 32607 | — |
| Southeastern Imaging & Diagnostics | Gainesville | Florida | 32607 | — |
| Southeastern Integrated Medical, PL, d/b/a Florida Medical Research Institute | Gainesville | Florida | 32607 | — |
| Jacksonville Center for Clincal Research | Jacksonville | Florida | 32216 | — |
| Memorial Hospital Jacksonville | Jacksonville | Florida | 32216 | — |
| Gold Coast Research, LLC | Plantation | Florida | 33317 | — |
| Marin E. Hale, M.D., P.A. | Plantation | Florida | 33317 | — |
| Sabiha Khan, M.D. | Plantation | Florida | 33324 | — |
| Kanner, Mendelson, Shteinman, LLC | West Palm Beach | Florida | 33407 | — |
| Radiant Research | West Palm Beach | Florida | 33407 | — |
| Rheumatology and Endocrinology Specialists of the Palm Beaches, P.A. | West Palm Beach | Florida | 33407 | — |
| North Georgia Clinical Research | Marietta | Georgia | 30060 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Preventive Medicine | Chicago | Illinois | 60611 | — |
| Rehabilitation Institue of Chicago | Chicago | Illinois | 60611 | — |
| NorthShore University HealthSystem | Evanston | Illinois | 60201 | — |
| NorthShore University HealthSystem | Glenview | Illinois | 60025 | — |
| Clinical Investigation Specialists, Inc. | Gurnee | Illinois | 60031 | — |
| Illinois Bone and Joint Institute, LLC | Morton Grove | Illinois | 60053 | — |
| The Arthritis Center | Springfield | Illinois | 62704 | — |
| NorthShore University HealthSystem | Vernon Hills | Illinois | 60061 | — |
| Ronald Keith Stegemoller, American Health Network | Avon | Indiana | 46123 | — |
| Floyd Memorial Hospital | New Albany | Indiana | 47150 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67205 | — |
| Family Medicine East, Chartered/Radiology | Wichita | Kansas | 67207 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67207 | — |
| Office of Manoj Kohli, M.D. | Lexington | Kentucky | 40517 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Commonwealth Biomedical Research, LLC | Madisonville | Kentucky | 42431 | — |
| TFD Research, LLC | Shreveport | Louisiana | 71115 | — |
| Rheumatology Associates | Portland | Maine | 04102 | — |
| The Center for Rheumatology and Bone Research | Rockville | Maryland | 20850 | — |
| The Center for Rheumatology and Bone Research | Wheaton | Maryland | 20902 | — |
| Miray Medical Center | Brockton | Massachusetts | 02301 | — |
| Phase III Clinical Research | Fall River | Massachusetts | 02720 | — |
| Fall River Clinical Research | Fall River | Massachusetts | 02721 | — |
| HCI Metromedic Walk-In | New Bedford | Massachusetts | 02740 | — |
| MedVadis Research Corporation | Wellesley Hills | Massachusetts | 02481-2106 | — |
| Fallon Clinic, Inc. (Drug Shipment) | Worcester | Massachusetts | 01605 | — |
| Fallon Clinic, Inc. | Worcester | Massachusetts | 01605 | — |
| Cadillac Clinical Research, LLC, located at Great Lakes Family Care | Cadillac | Michigan | 49601 | — |
| Arthritis and Osteoporosis Treatment and Research Center | Flowood | Mississippi | 39232 | — |
| Planters Clinic | Port Gibson | Mississippi | 39150 | — |
| North Mississippi Medical Center, Inc. | Tupelo | Mississippi | 38801 | — |
| Mercy Medical Group/Woodlake Research | Clarkson Valley | Missouri | 63011 | — |
| Dynamic Clinical Research, Inc. | Kansas City | Missouri | 64114 | — |
| Joan Prouty Moore, MD | Kansas City | Missouri | 64114 | — |
| Orthopaedic and Occupational Medicine | Kansas City | Missouri | 64114 | — |
| The Center for Pharmaceutical Research, P.C. | Kansas City | Missouri | 64114 | — |
| Affiliated Clinical Research, Inc. | Las Vegas | Nevada | 89106 | — |
| Office of Michael Mall, M.D. | Las Vegas | Nevada | 89109 | — |
| Nevada Imaging Centers | Las Vegas | Nevada | 89117 | — |
| Nevada Imaging Centers | Las Vegas | Nevada | 89118 | — |
| Office of Danka Michaels, MD | Las Vegas | Nevada | 89128 | — |
| Office of Stephen H. Miller, MD | Las Vegas | Nevada | 89144 | — |
| Regional Clinical Research, Inc. | Endwell | New York | 13760 | — |
| NYU Hospital for Joint Diseases | New York | New York | 10003 | — |
| VirtualScopics, Inc. | Rochester | New York | 14625 | — |
| Crouse Medical Practice, PLLC d/b/a Internist Associates of Central New York | Syracuse | New York | 13210 | — |
| Kernodle Clinic Inc. | Burlington | North Carolina | 27215 | — |
| Southeastern Radiology | Greensboro | North Carolina | 27407 | — |
| PharmQuest | Greensboro | North Carolina | 27408 | — |
| Research Institute of the Carolinas, PLLC | Mooresville | North Carolina | 28117 | — |
| PMG Research of Salisbury | Salisbury | North Carolina | 28144 | — |
| Piedmont Healthcare/Research | Statesville | North Carolina | 28625 | — |
| Carolina Arthritis Associates, PA | Wilmington | North Carolina | 28401 | — |
| PMG Research of Wilmington, LLC | Wilmington | North Carolina | 28401 | — |
| Internal Medicine Associates | Fargo | North Dakota | 58103 | — |
| Lillestol Research, LLC | Fargo | North Dakota | 58103 | — |
| Advantage Diagnostics | Beachwood | Ohio | 44122 | — |
| Rapid Medical Research, Inc. | Cleveland | Ohio | 44122 | — |
| Columbus Clinical Research, Inc. | Columbus | Ohio | 43213 | — |
| Optimed Research, LLC | Columbus | Ohio | 43235 | — |
| Lake Health Lyndhurst Clinic | Lyndhurst | Ohio | 44124 | — |
| East Penn Rheumatology Associates, PC | Bethlehem | Pennsylvania | 18015 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| BioImaging Technologies, Inc. | Newtown | Pennsylvania | 18940 | — |
| Memorial Hospital of Rhode Island | Pawtucket | Rhode Island | 02860 | — |
| Rheumatology Associates | Charleston | South Carolina | 29407 | — |
| Radiant Research, Inc. | Greer | South Carolina | 29651 | — |
| Parkway Medical Group | Fayetteville | Tennessee | 37334 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| D. Matthew Sellers MD PC | Knoxville | Tennessee | 37920 | — |
| Southwind Medical Specialists | Memphis | Tennessee | 38125 | — |
| Baylor Research Institute | Dallas | Texas | 75231 | — |
| Metroplex Clinical Research Center | Dallas | Texas | 75231 | — |
| Radiant Research San Antonio Northeast | San Antonio | Texas | 78217 | — |
| South Texas Radiology Imaging Center | San Antonio | Texas | 78217 | — |
| Oakwell Clinical Research, LLC | San Antonio | Texas | 78218 | — |
| Pivotal Research Centers | Midvale | Utah | 84047 | — |
| National Clinical Research - Norfolk, Inc. | Norfolk | Virginia | 23502 | — |
| National Clinical Research, Incorporated | Richmond | Virginia | 23294 | — |
| Advanced Pain Management | Virginia Beach | Virginia | 23454 | — |
| Tacoma Center for Arthritis Research, PS | Tacoma | Washington | 98405 | — |
| Clinical Investigation Specialists, Inc. | Kenosha | Wisconsin | 53142 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00565812, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 30, 2016 · Synced Nov 10, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00565812 live on ClinicalTrials.gov.