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Completed Phase 3 Interventional Results available

A Safety and Efficacy Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects

ClinicalTrials.gov ID: NCT00567255

Public ClinicalTrials.gov record NCT00567255. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 4:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double Blind, Placebo Controlled Study Comparing the Safety and Efficacy of Naltrexone Sustained Release (SR)/Bupropion Sustained Release (SR) and Placebo in Obese Subjects

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine whether the combination of naltrexone SR and bupropion SR is safe and effective in the treatment of obesity.

Study identification

NCT ID
NCT00567255
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Orexigen Therapeutics, Inc
Industry
Enrollment
1,496 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2007
Primary completion
May 31, 2009
Completion
May 31, 2009
Last update posted
Nov 20, 2014

2007 – 2009

United States locations

U.S. sites
36
U.S. states
26
U.S. cities
34
Facility City State ZIP Site status
Lovelace Scientific Resources Phoenix Arizona 85016
HOPE Research Institute Phoenix Arizona 85050
HealthStar Research Hot Springs Arkansas 71913
Northern California Research Carmichael California 98608
Sierra Medical Research Fresno California 93710
Pharmacology Research Institute Newport Beach California 92660
Center for Human Nutrition University of Colorado Health Sciences Center Denver Colorado 80220
Chase Medical Research, LLC Waterbury Connecticut 06708
George Washington University Washington D.C. District of Columbia 20037
Suncoast Clinical Research Palm Harbor Florida 34684
Comprehensive NeuroScience, Inc Atlanta Georgia 30328
Clinical Research Atlanta Stockbridge Georgia 30281
Northwest Indiana Center for Clinical Research Valparaiso Indiana 46383
Trover Center for Clinical Studies Madisonville Kentucky 42431
Nutrition and Weight Mangement Center Boston Medical Center Boston Massachusetts 02118
Milford Emergency Associates, Inc Milford Massachusetts 01757
Summit Research Network, Inc. Okemos Michigan 48864
Twin Cities Clinical Research Brooklyn Center Minnesota 55430
Mercy Health Research St Louis Missouri 63141
Radiant Research, Inc. St Louis Missouri 63141
Clinical Research Center of Nevada Las Vegas Nevada 89104
Endocrinology & Diabetes Consultants Dover New Hampshire 03820
Lovelace Scientific Resources Albuquerque New Mexico 87108
Central New York Clinical Research Manlius New York 13104
Comprehensive Weight Control Program New York New York 10021
Behavioral Medical Research Staten Island New York 10305
Metrolina Medical Research Charlotte North Carolina 28209
Patient Priority Cincinnati Ohio 45242
Wells Institute For Health Awareness Kettering Ohio 45429
The Portland Clinic Portland Oregon 97205
Geisinger Medical Center Danville Pennsylvania 17822
Mountain View Clinical Research Greer South Carolina 29349
Palmetto Medical Research Mt. Pleasant South Carolina 29464
Clinical Research Associates, Inc. Nashville Tennessee 37203
The Cooper Institute Dallas Texas 75230
Summit Research Network, Inc. Seattle Washington 98104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00567255, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 20, 2014 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00567255 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →