Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

ELND005 in Patients With Mild to Moderate Alzheimer's Disease

ClinicalTrials.gov ID: NCT00568776

Public ClinicalTrials.gov record NCT00568776. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 27, 2026, 3:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Safety and Efficacy Study of Oral ELND005 (AZD-103) in Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the dose-related safety and efficacy of multiple oral dosages of ELND005 as treatment for Alzheimer's disease (AD).

Study identification

NCT ID
NCT00568776
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
OPKO Health, Inc.
Industry
Enrollment
353 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2007
Primary completion
Apr 30, 2010
Completion
Apr 30, 2010
Last update posted
Oct 31, 2019

2007 – 2010

United States locations

U.S. sites
50
U.S. states
25
U.S. cities
47
Facility City State ZIP Site status
Banner Alzheimer's Institute Phoenix Arizona 85006 —
Sun Health Research Institute Sun City Arizona 85351 —
University of Arizona, Health Sciences Center, Dept. of Neurology Tucson Arizona 85724 —
Margolin Brain Institute Fresno California 93720 —
Collaborative NeuroScience Network, Inc. Garden Grove California 92845 —
UCLA Alzheimer's Disease Center, Dept. of Neurology Los Angeles California 90095 —
UC Irvine Medical Center Orange California 92868 —
UCSF Medical Center, Dept. of Neurology San Francisco California 94143 —
Yale University School of Medicine, Alzheimer's Disease Research Unit New Haven Connecticut 06510 —
Georgetown University Medical Center, Dept. of Neurology Washington D.C. District of Columbia 20057 —
Brain Matters Research, Inc. Delray Beach Florida 33445 —
Sunrise Clinical Research, Inc Hollywood Florida 33021 —
Miami Jewish Home and Hospital For The Aged Miami Florida 33137 —
Avision Research Associates, LLC Miami Florida 33173 —
Compass Research, LLC Orlando Florida 32806 —
Roskamp Institute Sarasota Florida 34243 —
Neurology Clinical Research, Inc. Sunrise Florida 33351 —
University of South Florida Suncoast Alzheimer's and Gerontology Center Tampa Florida 33617 —
Premiere Research Institute West Palm Beach Florida 33407 —
Emory University, Dept. of Neurology Atlanta Georgia 30329 —
Dekalb Neurology Associates, LLC Decatur Georgia 30033 —
Department of Neurology - Indiana University Medical Center Indianapolis Indiana 46202 —
University of Kansas Medical Center, Department of Neurology Kansas City Kansas 66160 —
Innovative Clinical Concepts Paducah Kentucky 42003 —
Brigham and Women's Hospital, Dept. of Neurology Boston Massachusetts 02115 —
University of Michigan, Taubman Health Care Center, Dept. of Neurology Ann Arbor Michigan 48109 —
University of Nevada School of Medicine Las Vegas Nevada 89102 —
Comprehensive Clinical Research Berlin New Jersey 08009 —
The Memory Enhancement Center of America, Inc. Eatontown New Jersey 07724 —
Global Medical Institutes Princeton New Jersey 08540 —
Albuquerque Neuroscience, Inc. Albuquerque New Mexico 87109 —
Upstate Clinical Research, LLC Albany New York 12205 —
Neurological Associates of Albany, PC Albany New York 12208 —
Mount Sinai Medical Center New York New York 10029 —
Columbia University Sergievsky Center New York New York 10032 —
AD-CARE, Monroe Community Hospital Rochester New York 14620 —
Raleigh Neurology Associates Raleigh North Carolina 27607 —
Neurology & Neuroscience Center of Ohio Toledo Ohio 43623 —
Medford Neurological and Spine Clinic Medford Oregon 97504 —
Summit Research Newtwork, Inc. Portland Oregon 97210 —
Abington Neurological Associates, Inc. Abington Pennsylvania 19001 —
The Clinical Trial Center, LLC Jenkintown Pennsylvania 19046 —
University of Pittsburgh Alzheimer Disease Research Clinic Pittsburgh Pennsylvania 15213 —
Butler Hospital, Memory and Aging Center Providence Rhode Island 02906 —
Alliance for Neuro Research, LLC dba Absher Neurology, PA Greenville South Carolina 29615 —
Radiant Research San Antonio San Antonio Texas 78229 —
University of Utah, Dept. of Neurology Salt Lake City Utah 84108 —
Clinical Neuroscience Research Associates, Inc-The Memory Clinic Bennington Vermont 05201 —
University of Vermont Medical Center, Fletcher Allen Health Care, Dept. of Neurology Burlington Vermont 05405 —
University of Virginia Health System Charlottesville Virginia 22903 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00568776, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 31, 2019 · Synced Sep 27, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00568776 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →