Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome
Public ClinicalTrials.gov record NCT00570128. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 10-Week, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Donepezil Hydrochloride (Aricept®) in the Treatment of the Cognitive Dysfunction Exhibited by Children With Down Syndrome
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether donepezil HCl is effective and safe in improving cognitive dysfunction exhibited by children and adolescents with Down syndrome (DS). Effectiveness will be measured by rating communication, daily living skills, and social skills and relationships in subjects aged 10 to 17.
Study identification
- NCT ID
- NCT00570128
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 129 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 10 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 16, 2007 (Actual)
- Primary completion
- Sep 5, 2008 (Actual)
- Completion
- Sep 5, 2008 (Actual)
- Last update posted
- Apr 19, 2021
2007 – 2008
United States locations
- U.S. sites
- 31
- U.S. states
- 19
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| Clinical Study Centers, L.L.C. | Little Rock | Arkansas | 72205 | — |
| Neufeld Medical Group, Inc. | Los Angeles | California | 90048 | — |
| Children's Hospital and Research Center at Oakland | Oakland | California | 94609 | — |
| University of California, Irvine Medical Center, Department of Pediatrics | Orange | California | 92868 | — |
| UCSD Pediatric Pharmacology Research Unit | San Diego | California | 92123 | — |
| Rocky Mountain Pediatrics | Lakewood | Colorado | 80214 | — |
| Neuropsychiatric Research Center of South West Florida | Fort Myers | Florida | 33912 | — |
| Miami Children's Hospital, Clinical Research Center | Miami | Florida | 33155-3009 | — |
| Community Research Foundation | Miami | Florida | 33155 | — |
| Miami Children's Hospital, Brain Institute | Miami | Florida | 33155 | — |
| Meridien Research | St. Petersburg | Florida | 33709 | — |
| Lazlo J. Mate, MD | West Palm Beach | Florida | 33407 | — |
| Child Neurology Associates, PC | Atlanta | Georgia | 30342 | — |
| Medical Genetics and Neuro Development Center | Zionsville | Indiana | 46077 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Saint Mayr's Health Care | Grand Rapids | Michigan | 49503 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101-2529 | — |
| Washington University School of Medicine, Division of Genetics and Genomic Medicine | St Louis | Missouri | 63110 | — |
| Midwest Children's Health Research Institute, LLC | Lincoln | Nebraska | 68504 | — |
| Clinical Research Center of New Jersey | Voorhees Township | New Jersey | 08043 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Metrohealth Medical Center, Division of Psychiatry | Cleveland | Ohio | 44109 | — |
| Valko and Associates | Toledo | Ohio | 43606 | — |
| Tulsa Clinical Research LLC | Tulsa | Oklahoma | 74104-5428 | — |
| Medical University of South Carolina, Division of Genetics and Developmental and Behavioral Pediatrics | Charleston | South Carolina | 29425 | — |
| Vanderbilt Children's Hospital | Nashville | Tennessee | 37232-9225 | — |
| Down Syndrome Clinic of Houston | Houston | Texas | 77030 | — |
| Alamo City Clinical Research, LLC | San Antonio | Texas | 78258 | — |
| Road Runner Research | San Antonio | Texas | 78258 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98004 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00570128, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 19, 2021 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00570128 live on ClinicalTrials.gov.