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Completed Phase 2 Interventional Results available

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome

ClinicalTrials.gov ID: NCT00570128

Public ClinicalTrials.gov record NCT00570128. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 2:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 10-Week, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Donepezil Hydrochloride (Aricept®) in the Treatment of the Cognitive Dysfunction Exhibited by Children With Down Syndrome

Study identification

NCT ID
NCT00570128
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Eisai Inc.
Industry
Enrollment
129 participants

Conditions and interventions

Conditions

Interventions

  • Donepezil HCl Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
10 Years to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 15, 2007
Primary completion
Sep 4, 2008
Completion
Sep 4, 2008
Last update posted
Apr 18, 2021

2007 – 2008

United States locations

U.S. sites
31
U.S. states
19
U.S. cities
28
Facility City State ZIP Site status
Phoenix Children's Hospital Phoenix Arizona 85016
Clinical Study Centers, L.L.C. Little Rock Arkansas 72205
Neufeld Medical Group, Inc. Los Angeles California 90048
Children's Hospital and Research Center at Oakland Oakland California 94609
University of California, Irvine Medical Center, Department of Pediatrics Orange California 92868
UCSD Pediatric Pharmacology Research Unit San Diego California 92123
Rocky Mountain Pediatrics Lakewood Colorado 80214
Neuropsychiatric Research Center of South West Florida Fort Myers Florida 33912
Miami Children's Hospital, Clinical Research Center Miami Florida 33155-3009
Community Research Foundation Miami Florida 33155
Miami Children's Hospital, Brain Institute Miami Florida 33155
Meridien Research St. Petersburg Florida 33709
Lazlo J. Mate, MD West Palm Beach Florida 33407
Child Neurology Associates, PC Atlanta Georgia 30342
Medical Genetics and Neuro Development Center Zionsville Indiana 46077
Hurley Medical Center Flint Michigan 48503
Saint Mayr's Health Care Grand Rapids Michigan 49503
Regions Hospital Saint Paul Minnesota 55101-2529
Washington University School of Medicine, Division of Genetics and Genomic Medicine St Louis Missouri 63110
Midwest Children's Health Research Institute, LLC Lincoln Nebraska 68504
Clinical Research Center of New Jersey Voorhees Township New Jersey 08043
Duke University Medical Center Durham North Carolina 27710
Metrohealth Medical Center, Division of Psychiatry Cleveland Ohio 44109
Valko and Associates Toledo Ohio 43606
Tulsa Clinical Research LLC Tulsa Oklahoma 74104-5428
Medical University of South Carolina, Division of Genetics and Developmental and Behavioral Pediatrics Charleston South Carolina 29425
Vanderbilt Children's Hospital Nashville Tennessee 37232-9225
Down Syndrome Clinic of Houston Houston Texas 77030
Alamo City Clinical Research, LLC San Antonio Texas 78258
Road Runner Research San Antonio Texas 78258
Northwest Clinical Research Center Bellevue Washington 98004

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00570128, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 18, 2021 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00570128 live on ClinicalTrials.gov.

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