Dosing Flexibility Study in Patients With Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT00580840. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IIIb Open-label run-in Double-blind, Placebo Controlled, Randomized Study to Evaluate the Safety/Efficacy of Certolizumab Pegol Administered Concomitantly With Stable-dose Methotrexate in Patients With Active Rheumatoid Arthritis.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
During the run-in period, CZP will be administered at 400 mg (2 injections) at Wks 0, 2, and 4 and 200 mg with placebo (1 injection placebo, 1 injection CZP) at Wks 6, 8, 10, 12, 14 and 16. At Wk 18 patients will be grouped as responders or non-responders based on results of the ACR20 at Week 16.
Study identification
- NCT ID
- NCT00580840
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 333 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2007
- Primary completion
- Nov 30, 2010
- Completion
- Feb 28, 2011
- Last update posted
- Aug 1, 2018
2007 – 2011
United States locations
- U.S. sites
- 50
- U.S. states
- 23
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Huntsville | Alabama | — | — |
| Not listed | Montgomery | Alabama | — | — |
| Not listed | Gilbert | Arizona | — | — |
| Not listed | Paradise Valley | Arizona | — | — |
| Not listed | Tucson | Arizona | — | — |
| Not listed | Little Rock | Arkansas | — | — |
| Not listed | Huntington Beach | California | — | — |
| Not listed | La Jolla | California | — | — |
| Not listed | Los Angeles | California | — | — |
| Not listed | Palm Desert | California | — | — |
| Not listed | Sacramento | California | — | — |
| Not listed | San Diego | California | — | — |
| Not listed | Colorado Springs | Colorado | — | — |
| Not listed | Aventura | Florida | — | — |
| Not listed | Clearwater | Florida | — | — |
| Not listed | Gainesville | Florida | — | — |
| Not listed | Jacksonville | Florida | — | — |
| Not listed | Jupiter | Florida | — | — |
| Not listed | Melbourne | Florida | — | — |
| Not listed | Sarasota | Florida | — | — |
| Not listed | Bogart | Georgia | — | — |
| Not listed | Morton Grove | Illinois | — | — |
| Not listed | Vernon Hills | Illinois | — | — |
| Not listed | Lexington | Kentucky | — | — |
| Not listed | Portland | Maine | — | — |
| Not listed | Haverhill | Massachusetts | — | — |
| Not listed | Pittsfield | Massachusetts | — | — |
| Not listed | Worcester | Massachusetts | — | — |
| Not listed | Rochester | Minnesota | — | — |
| Not listed | Kansas City | Missouri | — | — |
| Not listed | Lincoln | Nebraska | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Reno | Nevada | — | — |
| Not listed | Albany | New York | — | — |
| Not listed | Mineola | New York | — | — |
| Not listed | Syracuse | New York | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Monroe | North Carolina | — | — |
| Not listed | Wilmington | North Carolina | — | — |
| Not listed | Cleveland | Ohio | — | — |
| Not listed | Perrysburg | Ohio | — | — |
| Not listed | Norman | Oklahoma | — | — |
| Not listed | Oklahoma City | Oklahoma | — | — |
| Not listed | Duncansville | Pennsylvania | — | — |
| Not listed | Simpsonville | South Carolina | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Sugar Land | Texas | — | — |
| Not listed | Tyler | Texas | — | — |
| Not listed | Vancouver | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00580840, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 1, 2018 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00580840 live on ClinicalTrials.gov.