Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 2 Interventional

A Study of Mapatumumab in Combination With Paclitaxel and Carboplatin in Subjects With Non-small Cell Lung Cancer

ClinicalTrials.gov ID: NCT00583830

Public ClinicalTrials.gov record NCT00583830. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 12:56 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy and Safety of Mapatumumab in Combination With Carboplatin and Paclitaxel as First Line Therapy in Subjects With Advanced Non-Small Cell Lung Cancer (NSCLC)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy (disease response) and safety of mapatumumab in combination with carboplatin and paclitaxel as first line therapy in subjects with advanced non-small cell lung cancer (NSCLC).

Study identification

NCT ID
NCT00583830
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Human Genome Sciences Inc.
Industry
Enrollment
111 participants

Conditions and interventions

Interventions

Biological · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 2007 (Type not available)
Primary completion
Nov 2010 (Actual)
Completion
Feb 2011 (Actual)
Last update posted
Aug 8, 2013

2007 – 2011

United States locations

U.S. sites
16
U.S. states
12
U.S. cities
16
Facility City State ZIP Site status
Birmingham Hematology and Oncology Associates, LLC Birmingham Alabama 35213 —
Desert Hematology Oncology Medical Group, Inc. Rancho Mirage California 92270 —
University of Colorado Health Sciences Center Aurora Colorado 80045 —
Osceola Cancer Center Kissimmee Florida 34741 —
Palm Beach Cancer Institute West Palm Beach Florida 33401 —
Rush University Medical Center Chicago Illinois 60612 —
LaGrange Oncology Associates LaGrange Illinois 60525 —
Orchard Research, LLC Skokie Illinois 60076 —
Kentuckiana Cancer Institute, PLLC Louisville Kentucky 40202 —
University of Maryland, Greenebaum Cancer Center Baltimore Maryland 21201 —
Chevy Chase Health Care Chevy Chase Maryland 20815 —
Hackensack University Medical Center Hackensack New Jersey 07601 —
Medical University of South Carolina: Hollings Cancer Center Charleston South Carolina 29425 —
The Sarah Cannon Cancer Center Nashville Tennessee 37203 —
UT Health Science Center at San Antonio, Be Well Center San Antonio Texas 78229 —
Fairfax-Northern Virginia Hematology Oncology, PC Fairfax Virginia 22031 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00583830, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 8, 2013 · Synced Oct 29, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00583830 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →