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Completed Phase 2 Interventional

A Safety, Efficacy and Tolerability Study of SEP-225289

ClinicalTrials.gov ID: NCT00584974

Public ClinicalTrials.gov record NCT00584974. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:14 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Blind, Placebo-Controlled Study Examining The Safety, Efficacy, and Tolerability of SEP-225289 in Subjects With Major Depressive Disorder (Including Atypical and Melancholic Features)

Study identification

NCT ID
NCT00584974
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Enrollment
523 participants

Conditions and interventions

Interventions

  • SEP-225289 Drug
  • Venlafaxine Drug
  • placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2007
Primary completion
Apr 30, 2009
Completion
Apr 30, 2009
Last update posted
Feb 22, 2012

2007 – 2009

United States locations

U.S. sites
51
U.S. states
22
U.S. cities
46
Facility City State ZIP Site status
Not listed Little Rock Arkansas 72211
Not listed Arcadia California 91007
Not listed Beverly Hills California 90210
Not listed Costa Mesa California 92626
Not listed Garden Grove California 92845
Not listed Glendale California 91204
Not listed Irvine California 92618
Not listed Lafayette California 94549
Not listed Oceanside California 92056
Not listed San Diego California 92103
Not listed Upland California 91786
Not listed Denver Colorado 80204
Not listed Denver Colorado 80239
Not listed New Britain Connecticut 06050
Not listed Bradenton Florida 34208
Not listed Fort Myers Florida 33912
Not listed Jacksonville Florida 32216
Not listed Lauderhill Florida 33139
Not listed Maitland Florida 32751
Not listed North Miami Florida 33161
Not listed Sanford Florida 32771
Not listed Atlanta Georgia 30328
Not listed Atlanta Georgia 30341
Not listed Smyrna Georgia 30080
Not listed Park Ridge Illinois 60068
Not listed Lake Charles Louisiana 70601
Not listed Boston Massachusetts 02135
Not listed Braintree Massachusetts 02184
Not listed Flowood Mississippi 39232
Not listed Saint Charles Missouri 63301
Not listed Clementon New Jersey 08021
Not listed Albuquerque New Mexico 87109
Not listed Brooklyn New York 11235
Not listed New York New York 10021
Not listed New York New York 10023
Not listed New York New York 10075
Not listed The Bronx New York 10454
Not listed The Bronx New York 10467
Not listed Raleigh North Carolina 27609
Not listed Cincinnati Ohio 45227
Not listed Dayton Ohio 45408
Not listed Middleburg Heights Ohio 44130
Not listed Oklahoma City Oklahoma 73112
Not listed Portland Oregon 97210
Not listed Philadelphia Pennsylvania 19149
Not listed Austin Texas 78756
Not listed Dallas Texas 75231
Not listed Houston Texas 77040
Not listed Irving Texas 75062
Not listed Midlothian Virginia 23112
Not listed Seattle Washington 98104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00584974, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 22, 2012 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00584974 live on ClinicalTrials.gov.

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