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Completed Phase 4 Interventional Results available

Combining Medications to Enhance Depression Outcomes

ClinicalTrials.gov ID: NCT00590863

Public ClinicalTrials.gov record NCT00590863. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 16, 2026, 5:58 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Study identification

NCT ID
NCT00590863
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Enrollment
665 participants

Conditions and interventions

Interventions

  • Escitalopram + Bupropion SR Drug
  • SSRI + placebo Drug
  • Venlafaxine XR + Mirtazapine Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 29, 2008
Primary completion
Aug 31, 2009
Completion
Aug 31, 2009
Last update posted
Apr 22, 2014

2008 – 2009

United States locations

U.S. sites
15
U.S. states
13
U.S. cities
15
Facility City State ZIP Site status
Tuscalossa VA Mental Health Clinic Tuscaloosa Alabama 35404
Harbor UCLA Family Health Care Center Harbor City California 90710
UCLA Internal Medicine Clinic Los Angeles California 90024
Veterans Affairs Medical Center/FIRM Primary Care Clinic San Diego California 92161
Northwestern Psychiatric Outpatient Treatment Care Center Chicago Illinois 60611
Clinical Research Institute Wichita Kansas 67214
MGH/Northshore Medical Center (Salem Psychiatric Facility) Salem Massachusetts 01970
General Psychiatric Ambulatory Clinic Ann Arbor Michigan 48105
Irving Goldman Primary Care at North Shore Hospital New York New York 11040
UNC Chapel Hill Adult Diagnostic & Treatment Clinic Chapel Hill North Carolina 27599-7160
Laureate Psychiatric Clinic and Hospital Tulsa Oklahoma 74135
Bellefield Clinic of WPIC Pittsburgh Pennsylvania 15213
Vine Hill Community Clinic Nashville Tennessee 37212
UT Southwestern Family Medicine Clinic Dallas Texas 75390
VCU Outpatient Psychiatry Clinic Richmond Virginia 23298

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00590863, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 22, 2014 · Synced May 16, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00590863 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →