ClinicalTrials.gov record
Tamoxifen Citrate or Letrozole With or Without Bevacizumab in Treating Women With Stage IIIB or Stage IV Breast Cancer
ClinicalTrials.gov ID: NCT00601900
Public ClinicalTrials.gov record NCT00601900. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Endocrine Therapy With or Without Anti-VEGF Therapy: A Randomized, Phase III Trial of Endocrine Therapy Alone or Endocrine Therapy Plus Bevacizumab (NSC 704865) for Women With Hormone Receptor-Positive Advanced Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized phase III trial studies tamoxifen citrate or letrozole together with bevacizumab to see how well it works compared with tamoxifen citrate or letrozole alone in treating women with stage IIIB or stage IV breast cancer. Estrogen can cause the growth of breast cancer cells. Hormone therapy using tamoxifen citrate or letrozole may fight breast cancer by blocking the use of estrogen by the tumor cells. Immunotherapy with monoclonal antibodies, such as bevacizumab, may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. It is not yet known whether giving hormone therapy is more effective with or without bevacizumab in treating advanced breast cancer.
Study identification
- NCT ID
- NCT00601900
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 394 participants
Conditions and interventions
Conditions
Interventions
- Bevacizumab Biological
- Laboratory Biomarker Analysis Other
- Letrozole Drug
- Questionnaire Administration Other
- Tamoxifen Citrate Drug
Biological · Other · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 24, 2008 (Actual)
- Primary completion
- Jun 30, 2014 (Actual)
- Completion
- Jan 29, 2024 (Actual)
- Last update posted
- Aug 28, 2026
2008 – 2024
United States locations
- U.S. sites
- 521
- U.S. states
- 45
- U.S. cities
- 358
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Providence Hospital | Mobile | Alabama | 36608 | — |
| Sparks Regional Medical Center | Fort Smith | Arkansas | 72901 | — |
| East Bay Medical Oncology Hematology Medical Associates-Antioch | Antioch | California | 94531 | — |
| Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California | 94704 | — |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | 91505 | — |
| Mills-Peninsula Medical Center | Burlingame | California | 94010 | — |
| East Bay Radiation Oncology Center | Castro Valley | California | 94546 | — |
| Eden Hospital Medical Center | Castro Valley | California | 94546 | — |
| Valley Medical Oncology Consultants-Castro Valley | Castro Valley | California | 94546 | — |
| Adventist Health Cancer Care Center Chico | Chico | California | 95973 | — |
| Community Cancer Institute | Clovis | California | 93611 | — |
| Bay Area Breast Surgeons Inc | Emeryville | California | 94608 | — |
| Valley Medical Oncology Consultants-Fremont | Fremont | California | 94538 | — |
| Marin General Hospital | Greenbrae | California | 94904 | — |
| Los Angeles General Medical Center | Los Angeles | California | 90033 | — |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Contra Costa Regional Medical Center | Martinez | California | 94553-3156 | — |
| Fremont - Rideout Cancer Center | Marysville | California | 95901 | — |
| Memorial Medical Center | Modesto | California | 95355 | — |
| El Camino Hospital | Mountain View | California | 94040 | — |
| Sutter Cancer Research Consortium | Novato | California | 94945 | — |
| Highland General Hospital | Oakland | California | 94602 | — |
| Alta Bates Summit Medical Center - Summit Campus | Oakland | California | 94609 | — |
| Bay Area Tumor Institute | Oakland | California | 94609 | — |
| Hematology and Oncology Associates-Oakland | Oakland | California | 94609 | — |
| Tom K Lee Inc | Oakland | California | 94609 | — |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| East Bay Medical Oncology Hematology Medical Associates Inc-Pleasant Hill | Pleasant Hill | California | 94523 | — |
| John Muir Health Cancer Medical Group | Pleasant Hill | California | 94523 | — |
| Valley Care Health System - Pleasanton | Pleasanton | California | 94588 | — |
| Valley Medical Oncology Consultants | Pleasanton | California | 94588 | — |
| Pomona Valley Hospital Medical Center | Pomona | California | 91767 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Zuckerberg San Francisco General Hospital | San Francisco | California | 94110 | — |
| California Pacific Medical Center-Pacific Campus | San Francisco | California | 94115 | — |
| UCSF Medical Center-Mount Zion | San Francisco | California | 94115 | — |
| East Bay Medical Oncology Hematology Associates Inc | San Leandro | California | 94578 | — |
| Doctors Medical Center- JC Robinson Regional Cancer Center | San Pablo | California | 94806 | — |
| Saint Helena Hospital | St. Helena | California | 94574 | — |
| Gene Upshaw Memorial Tahoe Forest Cancer Center | Truckee | California | 96161 | — |
| Northbay Cancer Center | Vacaville | California | 95687 | — |
| Sutter Solano Medical Center/Cancer Center | Vallejo | California | 94589 | — |
| The Medical Center of Aurora | Aurora | Colorado | 80012 | — |
| Boulder Community Hospital | Boulder | Colorado | 80301 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| AdventHealth Porter | Denver | Colorado | 80210 | — |
| Presbyterian - Saint Lukes Medical Center - Health One | Denver | Colorado | 80218 | — |
| Saint Joseph Hospital - Cancer Centers of Colorado | Denver | Colorado | 80218 | — |
| Rose Medical Center | Denver | Colorado | 80220 | — |
| Western States Cancer Research NCORP | Denver | Colorado | 80222 | — |
| Swedish Medical Center | Englewood | Colorado | 80113 | — |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado | 81501 | — |
| Banner North Colorado Medical Center | Greeley | Colorado | 80631 | — |
| Saint Anthony Hospital | Lakewood | Colorado | 80228 | — |
| AdventHealth Littleton | Littleton | Colorado | 80122 | — |
| Sky Ridge Medical Center | Lone Tree | Colorado | 80124 | — |
| Longmont United Hospital | Longmont | Colorado | 80501 | — |
| Banner McKee Medical Center | Loveland | Colorado | 80539 | — |
| Saint Mary Corwin Medical Center | Pueblo | Colorado | 81004 | — |
| North Suburban Medical Center | Thornton | Colorado | 80229 | — |
| Intermountain Health Lutheran Hospital | Wheat Ridge | Colorado | 80401 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Smilow Cancer Hospital Care Center at Saint Francis | Hartford | Connecticut | 06105 | — |
| Middlesex Hospital | Middletown | Connecticut | 06457 | — |
| The Hospital of Central Connecticut | New Britain | Connecticut | 06050 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Stamford Hospital/Bennett Cancer Center | Stamford | Connecticut | 06904 | — |
| Beebe Medical Center | Lewes | Delaware | 19958 | — |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | — |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | — |
| Boca Raton Regional Hospital | Boca Raton | Florida | 33486 | — |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| Florida Cancer Specialists-Gainesville Cancer Center | Gainesville | Florida | 32605 | — |
| Jupiter Medical Center | Jupiter | Florida | 33458 | — |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| University Cancer and Blood Center LLC | Athens | Georgia | 30607 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Atlanta Regional CCOP | Atlanta | Georgia | 30342 | — |
| Emory Saint Joseph's Hospital | Atlanta | Georgia | 30342 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| Augusta University Medical Center | Augusta | Georgia | 30912 | — |
| WellStar Cobb Hospital | Austell | Georgia | 30106 | — |
| John B Amos Cancer Center | Columbus | Georgia | 31904 | — |
| Emory Decatur Hospital | Decatur | Georgia | 30033 | — |
| Dublin Hematology Oncology Care PC | Dublin | Georgia | 31021 | — |
| Piedmont Fayette Hospital | Fayetteville | Georgia | 30214 | — |
| Eisenhower Army Medical Center | Fort Eisenhower | Georgia | 30905 | — |
| Northeast Georgia Medical Center-Gainesville | Gainesville | Georgia | 30501 | — |
| Northside Hospital - Gwinnett | Lawrenceville | Georgia | 30046 | — |
| Atrium Health Navicent | Macon | Georgia | 31201 | — |
| Wellstar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| Southern Regional Medical Center | Riverdale | Georgia | 30274 | — |
| Harbin Clinic Medical Oncology and Clinical Research | Rome | Georgia | 30165 | — |
| Hawaii Cancer Care Inc - Waterfront Plaza | Honolulu | Hawaii | 96813 | — |
| Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Straub Clinic and Hospital | Honolulu | Hawaii | 96813 | — |
| University of Hawaii Cancer Center | Honolulu | Hawaii | 96813 | — |
| Queen's Cancer Center - Kuakini | Honolulu | Hawaii | 96817 | — |
| The Cancer Center of Hawaii-Liliha | Honolulu | Hawaii | 96817 | — |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | — |
| Maui Memorial Medical Center | Wailuku | Hawaii | 96793 | — |
| Pacific Cancer Institute of Maui | Wailuku | Hawaii | 96793 | — |
| Pali Momi Medical Center | ‘Aiea | Hawaii | 96701 | — |
| OSF Saint Anthony's Health Center | Alton | Illinois | 62002 | — |
| Rush - Copley Medical Center | Aurora | Illinois | 60504 | — |
| OSF Saint Joseph Medical Center | Bloomington | Illinois | 61701 | — |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | — |
| Graham Hospital Association | Canton | Illinois | 61520 | — |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | — |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | — |
| Memorial Hospital | Carthage | Illinois | 62321 | — |
| Mount Sinai Hospital Medical Center | Chicago | Illinois | 60608 | — |
| John H Stroger Jr Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Mercy Hospital and Medical Center | Chicago | Illinois | 60616 | — |
| Presence Resurrection Medical Center | Chicago | Illinois | 60631 | — |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | — |
| Advocate Illinois Masonic Medical Center | Chicago | Illinois | 60657 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Heartland Cancer Research NCORP | Decatur | Illinois | 62526 | — |
| Advocate Good Samaritan Hospital | Downers Grove | Illinois | 60515 | — |
| Ascension Alexian Brothers - Elk Grove Village | Elk Grove Village | Illinois | 60007 | — |
| Elmhurst Memorial Hospital | Elmhurst | Illinois | 60126 | — |
| Eureka Hospital | Eureka | Illinois | 61530 | — |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | — |
| Freeport Memorial Hospital/Leonard C Ferguson Cancer Center | Freeport | Illinois | 61032 | — |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Illinois CancerCare-Havana | Havana | Illinois | 62644 | — |
| Mason District Hospital | Havana | Illinois | 62644 | — |
| Duly Health and Care Joliet | Joliet | Illinois | 60435 | — |
| Presence Saint Mary's Hospital | Kankakee | Illinois | 60901 | — |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | — |
| AMITA Health Adventist Medical Center | La Grange | Illinois | 60525 | — |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | — |
| Mcdonough District Hospital | Macomb | Illinois | 61455 | — |
| Garneau, Stewart C MD (UIA Investigator) | Moline | Illinois | 61265 | — |
| Porubcin, Michael MD (UIA Investigator) | Moline | Illinois | 61265 | — |
| Sharis, Christine M MD (UIA Investigator) | Moline | Illinois | 61265 | — |
| Spector, David MD (UIA Investigator) | Moline | Illinois | 61265 | — |
| Stoffel, Thomas J MD (UIA Investigator) | Moline | Illinois | 61265 | — |
| Trinity Medical Center | Moline | Illinois | 61265 | — |
| Holy Family Medical Center | Monmouth | Illinois | 61462 | — |
| Illinois CancerCare-Monmouth | Monmouth | Illinois | 61462 | — |
| SSM Health Good Samaritan | Mount Vernon | Illinois | 62864 | — |
| Carle BroMenn Medical Center | Normal | Illinois | 61761 | — |
| Carle Cancer Institute Normal | Normal | Illinois | 61761 | — |
| Illinois CancerCare-Community Cancer Center | Normal | Illinois | 61761 | — |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | — |
| Ottawa Regional Hospital and Healthcare Center | Ottawa | Illinois | 61350 | — |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | — |
| OSF Saint Francis Radiation Oncology at Pekin | Pekin | Illinois | 61554 | — |
| Proctor Hospital | Peoria | Illinois | 61614 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | — |
| Illinois Valley Hospital | Peru | Illinois | 61354 | — |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | — |
| Perry Memorial Hospital | Princeton | Illinois | 61356 | — |
| Illinois CancerCare-Spring Valley | Spring Valley | Illinois | 61362 | — |
| Springfield Memorial Hospital | Springfield | Illinois | 62781 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Franciscan Saint Francis Health-Beech Grove | Beech Grove | Indiana | 46107 | — |
| Elkhart Clinic | Elkhart | Indiana | 46514-2098 | — |
| Michiana Hematology Oncology PC-Elkhart | Elkhart | Indiana | 46514 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Fort Wayne Medical Oncology and Hematology Inc-Parkview | Fort Wayne | Indiana | 46845 | — |
| Ascension Saint Vincent Indianapolis Hospital | Indianapolis | Indiana | 46260 | — |
| Community Howard Regional Health | Kokomo | Indiana | 46904 | — |
| IU Health La Porte Hospital | La Porte | Indiana | 46350 | — |
| IU Health Arnett Cancer Care | Lafayette | Indiana | 47904 | — |
| Franciscan Saint Anthony Health-Michigan City | Michigan City | Indiana | 46360 | — |
| Michiana Hematology Oncology PC-Mishawaka | Mishawaka | Indiana | 46545 | — |
| Saint Joseph Regional Medical Center-Mishawaka | Mishawaka | Indiana | 46545 | — |
| Michiana Hematology Oncology PC-Plymouth | Plymouth | Indiana | 46563 | — |
| Reid Health | Richmond | Indiana | 47374 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Northern Indiana Cancer Research Consortium | South Bend | Indiana | 46628 | — |
| Michiana Hematology Oncology PC-Westville | Westville | Indiana | 46391 | — |
| McFarland Clinic - Ames | Ames | Iowa | 50010 | — |
| Constantinou, Costas L MD (UIA Investigator) | Bettendorf | Iowa | 52722 | — |
| University of Iowa Healthcare Cancer Services Quad Cities | Bettendorf | Iowa | 52722 | — |
| UI Health Care Mission Cancer and Blood - West Des Moines Clinic | Clive | Iowa | 50325 | — |
| Mercy Capitol | Des Moines | Iowa | 50307 | — |
| Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Iowa-Wide Oncology Research Coalition NCORP | Des Moines | Iowa | 50309 | — |
| UI Health Care Mission Cancer and Blood - Des Moines Clinic | Des Moines | Iowa | 50309 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| UI Health Care Mission Cancer and Blood - Laurel Clinic | Des Moines | Iowa | 50314 | — |
| Iowa Lutheran Hospital | Des Moines | Iowa | 50316 | — |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | — |
| Ottumwa Regional Health Center | Ottumwa | Iowa | 52501 | — |
| Siouxland Regional Cancer Center | Sioux City | Iowa | 51101 | — |
| Mercy Medical Center-Sioux City | Sioux City | Iowa | 51102 | — |
| Saint Luke's Regional Medical Center | Sioux City | Iowa | 51104 | — |
| HaysMed | Hays | Kansas | 67601 | — |
| Hutchinson Regional Medical Center | Hutchinson | Kansas | 67502 | — |
| University of Kansas Cancer Center | Kansas City | Kansas | 66160 | — |
| Olathe Cancer Center | Olathe | Kansas | 66061 | — |
| Mercy Hospital Pittsburg | Pittsburg | Kansas | 66762 | — |
| Salina Regional Health Center | Salina | Kansas | 67401 | — |
| Cotton O'Neil Cancer Center / Stormont Vail Health | Topeka | Kansas | 66606 | — |
| University of Kansas Health System Saint Francis Campus | Topeka | Kansas | 66606 | — |
| Our Lady Bellefonte Hospital | Ashland | Kentucky | 41101 | — |
| Doctors Carrol, Sheth, Raghavan | Louisville | Kentucky | 40215 | — |
| Hematology/Oncology Clinic PLLC | Baton Rouge | Louisiana | 70809 | — |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809 | — |
| Ochsner Health Center-Summa | Baton Rouge | Louisiana | 70809 | — |
| Ochsner Health Center-Covington | Covington | Louisiana | 70433 | — |
| Louisiana State University Health Science Center | New Orleans | Louisiana | 70112 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| Ochsner Baptist Medical Center | New Orleans | Louisiana | 70115 | — |
| Ochsner Medical Center Jefferson | New Orleans | Louisiana | 70121 | — |
| Harold Alfond Center for Cancer Care | Augusta | Maine | 04330 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| New England Cancer Specialists | Westbrook | Maine | 04092 | — |
| University of Maryland/Greenebaum Cancer Center | Baltimore | Maryland | 21201 | — |
| Veterans Administration Medical Center-Baltimore | Baltimore | Maryland | 21201 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | — |
| Christiana Care - Union Hospital | Elkton | Maryland | 21921 | — |
| Frederick Memorial Hospital | Frederick | Maryland | 21701 | — |
| Meritus Medical Center | Hagerstown | Maryland | 21742 | — |
| Kaiser Permanente - Largo Medical Center | Largo | Maryland | 20774 | — |
| Kaiser Permanente Lutherville - Timonium Medical Center | Lutherville | Maryland | 21093 | — |
| Kaiser Permanente - Shady Grove Medical Center | Rockville | Maryland | 20850 | — |
| Holy Cross Hospital | Silver Spring | Maryland | 20910 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Addison Gilbert Hospital | Gloucester | Massachusetts | 01930 | — |
| Cape Cod Hospital | Hyannis | Massachusetts | 02601 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | — |
| Holy Family Hospital | Methuen | Massachusetts | 01844 | — |
| Dana-Farber/Brigham and Women's Cancer Center at Milford Regional | Milford | Massachusetts | 01757 | — |
| Newton-Wellesley Hospital | Newton | Massachusetts | 02462 | — |
| Michigan Cancer Research Consortium NCORP | Ann Arbor | Michigan | 48106 | — |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor | Ann Arbor | Michigan | 48106 | — |
| Bronson Battle Creek | Battle Creek | Michigan | 49017 | — |
| McLaren Cancer Institute-Bay City | Bay City | Michigan | 48706 | — |
| Spectrum Health Big Rapids Hospital | Big Rapids | Michigan | 49307 | — |
| Corewell Health Dearborn Hospital | Dearborn | Michigan | 48124 | — |
| Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Henry Ford Health Saint John Hospital | Detroit | Michigan | 48236 | — |
| Michigan State University Clinical Center | East Lansing | Michigan | 48824 | — |
| OSF Saint Francis Hospital and Medical Group | Escanaba | Michigan | 49829 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Genesys Regional Medical Center-West Flint Campus | Flint | Michigan | 48532 | — |
| McLaren Cancer Institute-Flint | Flint | Michigan | 48532 | — |
| Cancer Research Consortium of West Michigan NCORP | Grand Rapids | Michigan | 49503 | — |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Grand Rapids | Michigan | 49503 | — |
| Trinity Health Grand Rapids Hospital | Grand Rapids | Michigan | 49503 | — |
| Allegiance Health | Jackson | Michigan | 49201 | — |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Ascension Borgess Hospital | Kalamazoo | Michigan | 49048 | — |
| Karmanos Cancer Institute at McLaren Greater Lansing | Lansing | Michigan | 48910 | — |
| University of Michigan Health - Sparrow Lansing | Lansing | Michigan | 48912 | — |
| Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | 48154 | — |
| UP Health System Marquette | Marquette | Michigan | 49855 | — |
| MyMichigan Medical Center Midland | Midland | Michigan | 48670 | — |
| Mercy Health Partners-Hackley Campus | Muskegon | Michigan | 49442 | — |
| Trinity Health Muskegon Hospital | Muskegon | Michigan | 49444 | — |
| Corewell Health Lakeland Hospitals - Niles Hospital | Niles | Michigan | 49120 | — |
| McLaren Cancer Institute-Northern Michigan | Petoskey | Michigan | 49770 | — |
| Trinity Health Saint Joseph Mercy Oakland Hospital | Pontiac | Michigan | 48341 | — |
| Lake Huron Medical Center | Port Huron | Michigan | 48060 | — |
| MyMichigan Medical Center Saginaw | Saginaw | Michigan | 48601 | — |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | — |
| Corewell Health Lakeland Hospitals - Saint Joseph Hospital | Saint Joseph | Michigan | 49085 | — |
| Henry Ford Health Providence Southfield Hospital | Southfield | Michigan | 48075 | — |
| Munson Medical Center | Traverse City | Michigan | 49684 | — |
| Henry Ford Health Warren Hospital | Warren | Michigan | 48093 | — |
| University of Michigan Health - West | Wyoming | Michigan | 49519 | — |
| Medini, Eitan MD (UIA Investigator) | Alexandria | Minnesota | 56308 | — |
| Essentia Health Cancer Center | Duluth | Minnesota | 55805 | — |
| Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | 55805 | — |
| Miller-Dwan Hospital | Duluth | Minnesota | 55805 | — |
| Etzell, Paul S MD (UIA Investigator) | Fergus Falls | Minnesota | 56537 | — |
| Swenson, Wade II, MD (UIA Investigator) | Fergus Falls | Minnesota | 56537 | — |
| Mayo Clinic Health Systems-Mankato | Mankato | Minnesota | 56001 | — |
| Coborn Cancer Center at Saint Cloud Hospital | Saint Cloud | Minnesota | 56303 | — |
| Saint Cloud Hospital | Saint Cloud | Minnesota | 56303 | — |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Singing River Hospital | Pascagoula | Mississippi | 39581 | — |
| Central Care Cancer Center - Bolivar | Bolivar | Missouri | 65613 | — |
| Cox Cancer Center Branson | Branson | Missouri | 65616 | — |
| Southeast Missouri Hospital | Cape Girardeau | Missouri | 63701 | — |
| Mercy Cancer Center - Cape Girardeau | Cape Girardeau | Missouri | 63703 | — |
| Saint Francis Medical Center | Cape Girardeau | Missouri | 63703 | — |
| MU Health - University Hospital/Ellis Fischel Cancer Center | Columbia | Missouri | 65212 | — |
| MU Health Care Goldschmidt Cancer Center | Jefferson City | Missouri | 65109 | — |
| Freeman Health System | Joplin | Missouri | 64804 | — |
| University Health Truman Medical Center | Kansas City | Missouri | 64108 | — |
| Phelps Health Delbert Day Cancer Institute | Rolla | Missouri | 65401 | — |
| Cancer Research for the Ozarks NCORP | Springfield | Missouri | 65804 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| CoxHealth South Hospital | Springfield | Missouri | 65807 | — |
| Saint Louis Cancer and Breast Institute-South City | St Louis | Missouri | 63109 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Comprehensive Cancer Care PC | St Louis | Missouri | 63141 | — |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | — |
| Saint Louis-Cape Girardeau CCOP | St Louis | Missouri | 63141 | — |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | — |
| Northern Rockies Radiation Oncology Center | Billings | Montana | 59101 | — |
| Saint Vincent Healthcare | Billings | Montana | 59101 | — |
| Montana Cancer Consortium NCORP | Billings | Montana | 59102 | — |
| Saint Vincent Frontier Cancer Center | Billings | Montana | 59102 | — |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | — |
| Saint James Community Hospital and Cancer Treatment Center | Butte | Montana | 59701 | — |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Berdeaux, Donald MD (UIA Investigator) | Great Falls | Montana | 59405 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Northern Montana Hospital | Havre | Montana | 59501 | — |
| Saint Peter's Community Hospital | Helena | Montana | 59601 | — |
| Glacier Oncology PLLC | Kalispell | Montana | 59901 | — |
| Kalispell Medical Oncology | Kalispell | Montana | 59901 | — |
| Logan Health Medical Center | Kalispell | Montana | 59901 | — |
| Montana Cancer Specialists | Missoula | Montana | 59802 | — |
| Saint Patrick Hospital - Community Hospital | Missoula | Montana | 59802 | — |
| Community Medical Center | Missoula | Montana | 59804 | — |
| Guardian Oncology and Center for Wellness | Missoula | Montana | 59804 | — |
| Nebraska Cancer Specialists/Oncology Hematology West PC | Grand Island | Nebraska | 68803 | — |
| Nebraska Cancer Research Center | Lincoln | Nebraska | 68510 | — |
| Great Plains Health Callahan Cancer Center | North Platte | Nebraska | 69101 | — |
| Missouri Valley Cancer Consortium | Omaha | Nebraska | 68106 | — |
| Alegent Health Immanuel Medical Center | Omaha | Nebraska | 68122 | — |
| Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | — |
| Creighton University Medical Center | Omaha | Nebraska | 68131 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| New Hampshire Oncology Hematology PA-Concord | Concord | New Hampshire | 03301 | — |
| Cheshire Medical Center-Dartmouth-Hitchcock Keene | Keene | New Hampshire | 03431 | — |
| LRGHealthcare-Lakes Region General Hospital | Laconia | New Hampshire | 03246 | — |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center | Lebanon | New Hampshire | 03756 | — |
| Solinsky Center for Cancer Care | Manchester | New Hampshire | 03103 | — |
| Saint Joseph Hospital | Nashua | New Hampshire | 03060 | — |
| Cooper Hospital University Medical Center | Camden | New Jersey | 08103 | — |
| CentraState Medical Center | Freehold | New Jersey | 07728 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| Overlook Hospital | Summit | New Jersey | 07902 | — |
| Inspira Medical Center Vineland | Vineland | New Jersey | 08360 | — |
| Hematology Oncology Associates of Central New York-East Syracuse | East Syracuse | New York | 13057 | — |
| Elmhurst Hospital Center | Elmhurst | New York | 11373 | — |
| Arnot Ogden Medical Center/Falck Cancer Center | Elmira | New York | 14905 | — |
| Adirondack Cancer Center | Glens Falls | New York | 12801 | — |
| Queens Hospital Center | Jamaica | New York | 11432 | — |
| Mount Sinai Union Square | New York | New York | 10003 | — |
| Mount Sinai West | New York | New York | 10019 | — |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| Ralph Lauren Center for Cancer Care and Prevention | New York | New York | 10035 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| NYP/Weill Cornell Medical Center | New York | New York | 10065 | — |
| Highland Hospital | Rochester | New York | 14620 | — |
| Interlakes Foundation Inc-Rochester | Rochester | New York | 14623 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Staten Island University Hospital | Staten Island | New York | 10305 | — |
| Montefiore Medical Center-Weiler Hospital | The Bronx | New York | 10461 | — |
| Montefiore Medical Center-Wakefield Campus | The Bronx | New York | 10466 | — |
| Montefiore Medical Center - Moses Campus | The Bronx | New York | 10467 | — |
| Faxton-Saint Luke's Healthcare | Utica | New York | 13502 | — |
| Randolph Hospital | Asheboro | North Carolina | 27203 | — |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | — |
| Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | 28203 | — |
| Wayne Memorial Hospital | Goldsboro | North Carolina | 27534 | — |
| Cone Health Cancer Center | Greensboro | North Carolina | 27403 | — |
| ECU Health Oncology Kinston | Kinston | North Carolina | 28501 | — |
| Annie Penn Memorial Hospital | Reidsville | North Carolina | 27320 | — |
| Rutherford Hospital | Rutherfordton | North Carolina | 28139 | — |
| Southeast Clinical Oncology Research Consortium NCORP | Winston-Salem | North Carolina | 27104 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Mid Dakota Clinic | Bismarck | North Dakota | 58501 | — |
| Saint Alexius Medical Center | Bismarck | North Dakota | 58501 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Altru Cancer Center | Grand Forks | North Dakota | 58201 | — |
| Trinity Cancer Care Center | Minot | North Dakota | 58701 | — |
| Mary Rutan Hospital | Bellefontaine | Ohio | 43311 | — |
| Aultman Health Foundation | Canton | Ohio | 44710 | — |
| Adena Regional Medical Center | Chillicothe | Ohio | 45601 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| Columbus NCI Community Oncology Research Program | Columbus | Ohio | 43215 | — |
| Grant Medical Center | Columbus | Ohio | 43215 | — |
| Mount Carmel Health Center West | Columbus | Ohio | 43222 | — |
| Doctors Hospital | Columbus | Ohio | 43228 | — |
| Grandview Hospital | Dayton | Ohio | 45405 | — |
| Good Samaritan Hospital - Dayton | Dayton | Ohio | 45406 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Miami Valley Hospital North | Dayton | Ohio | 45415 | — |
| Dayton Veterans Affairs Medical Center | Dayton | Ohio | 45428 | — |
| Grady Memorial Hospital | Delaware | Ohio | 43015 | — |
| Blanchard Valley Hospital | Findlay | Ohio | 45840 | — |
| Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | 45005-1066 | — |
| Wayne Hospital | Greenville | Ohio | 45331 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Fairfield Medical Center | Lancaster | Ohio | 43130 | — |
| Saint Rita's Medical Center | Lima | Ohio | 45801 | — |
| Marietta Memorial Hospital | Marietta | Ohio | 45750 | — |
| Knox Community Hospital | Mount Vernon | Ohio | 43050 | — |
| Licking Memorial Hospital | Newark | Ohio | 43055 | — |
| Southern Ohio Medical Center | Portsmouth | Ohio | 45662 | — |
| Springfield Regional Medical Center | Springfield | Ohio | 45504 | — |
| Upper Valley Medical Center | Troy | Ohio | 45373 | — |
| Saint Ann's Hospital | Westerville | Ohio | 43081 | — |
| Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center | Wilmington | Ohio | 45177 | — |
| Greene Memorial Hospital | Xenia | Ohio | 45385 | — |
| Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | 43701 | — |
| Natalie Warren Bryant Cancer Center at Saint Francis | Tulsa | Oklahoma | 74136 | — |
| Saint Charles Health System | Bend | Oregon | 97701 | — |
| Clackamas Radiation Oncology Center | Clackamas | Oregon | 97015 | — |
| Legacy Mount Hood Medical Center | Gresham | Oregon | 97030 | — |
| Providence Milwaukie Hospital | Milwaukie | Oregon | 97222 | — |
| Providence Newberg Medical Center | Newberg | Oregon | 97132 | — |
| Providence Willamette Falls Medical Center | Oregon City | Oregon | 97045 | — |
| Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | 97210 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Adventist Medical Center | Portland | Oregon | 97216 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Kaiser Permanente Northwest | Portland | Oregon | 97227 | — |
| Legacy Emanuel Hospital and Health Center | Portland | Oregon | 97227 | — |
| Legacy Meridian Park Hospital | Tualatin | Oregon | 97062 | — |
| Jefferson Abington Hospital | Abington | Pennsylvania | 19001 | — |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19010 | — |
| Doylestown Hospital | Doylestown | Pennsylvania | 18901 | — |
| Paoli Memorial Hospital | Paoli | Pennsylvania | 19301 | — |
| West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| University of Pittsburgh Cancer Institute (UPCI) | Pittsburgh | Pennsylvania | 15232 | — |
| Guthrie Medical Group PC-Robert Packer Hospital | Sayre | Pennsylvania | 18840 | — |
| Mercy Hospital | Scranton | Pennsylvania | 18501 | — |
| Scranton Hematology Oncology | Scranton | Pennsylvania | 18510 | — |
| Grand View Hospital | Sellersville | Pennsylvania | 18960 | — |
| Chester County Hospital | West Chester | Pennsylvania | 19380 | — |
| Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| UPMC Susquehanna | Williamsport | Pennsylvania | 17701 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| Hematology and Oncology Associates of Rhode Island Inc | Cranston | Rhode Island | 02920 | — |
| Memorial Hospital of Rhode Island | Pawtucket | Rhode Island | 02860 | — |
| Kent Hospital | Warwick | Rhode Island | 02886 | — |
| AnMed Health Cancer Center | Anderson | South Carolina | 29621 | — |
| AnMed Health Hospital | Anderson | South Carolina | 29621 | — |
| McLeod Regional Medical Center | Florence | South Carolina | 29506 | — |
| Saint Francis Hospital | Greenville | South Carolina | 29601 | — |
| Spartanburg Medical Center | Spartanburg | South Carolina | 29303 | — |
| Avera Cancer Institute-Aberdeen | Aberdeen | South Dakota | 57401 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | 57104 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Medical X-Ray Center | Sioux Falls | South Dakota | 57105 | — |
| Avera McKennan Hospital and University Health Center | Sioux Falls | South Dakota | 57117-5045 | — |
| Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | 57117-5134 | — |
| Erlanger Medical Center | Chattanooga | Tennessee | 37403 | — |
| Doctor's Hospital of Laredo | Laredo | Texas | 78041 | — |
| Sentara Martha Jefferson Hospital | Charlottesville | Virginia | 22901 | — |
| Danville Regional Medical Center | Danville | Virginia | 24541 | — |
| Kaiser Permanente - Fair Oaks Medical Center | Fairfax | Virginia | 22033 | — |
| Providence Regional Cancer System-Centralia | Centralia | Washington | 98531 | — |
| Saint Francis Hospital | Federal Way | Washington | 98003 | — |
| Saint Clare Hospital | Lakewood | Washington | 98499 | — |
| Providence - Saint Peter Hospital | Olympia | Washington | 98506-5166 | — |
| MultiCare Good Samaritan Hospital | Puyallup | Washington | 98372 | — |
| Providence Sacred Heart Medical Center and Children's Hospital | Spokane | Washington | 99204 | — |
| Providence Holy Family Hospital | Spokane | Washington | 99208 | — |
| Rockwood Clinic | Spokane | Washington | 99220 | — |
| MultiCare Allenmore Hospital | Tacoma | Washington | 98405 | — |
| Saint Joseph Medical Center | Tacoma | Washington | 98405 | — |
| PeaceHealth Southwest Medical Center | Vancouver | Washington | 98664 | — |
| West Virginia University Charleston Division | Charleston | West Virginia | 25304 | — |
| Wheeling Hospital/Schiffler Cancer Center | Wheeling | West Virginia | 26003 | — |
| Langlade Hospital and Cancer Center | Antigo | Wisconsin | 54409 | — |
| Aurora Cancer Care-Southern Lakes VLCC | Burlington | Wisconsin | 53105 | — |
| Marshfield Clinic-Chippewa Center | Chippewa Falls | Wisconsin | 54729 | — |
| Marshfield Clinic Cancer Center at Sacred Heart | Eau Claire | Wisconsin | 54701 | — |
| Aurora Cancer Care-Franklin | Franklin | Wisconsin | 53132 | — |
| Aurora Health Care Germantown Health Center | Germantown | Wisconsin | 53022 | — |
| Aurora Cancer Care-Glendale | Glendale | Wisconsin | 53212 | — |
| Green Bay Oncology at Saint Vincent Hospital | Green Bay | Wisconsin | 54301-3526 | — |
| Bellin Memorial Hospital | Green Bay | Wisconsin | 54301 | — |
| Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | 54301 | — |
| Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | 54303 | — |
| Aurora BayCare Medical Center | Green Bay | Wisconsin | 54311 | — |
| Mercyhealth Hospital and Cancer Center - Janesville | Janesville | Wisconsin | 53548 | — |
| Aurora Cancer Care-Kenosha South | Kenosha | Wisconsin | 53142 | — |
| Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| SSM Health Dean Medical Group - South Madison Campus | Madison | Wisconsin | 53715 | — |
| Holy Family Memorial Hospital | Manitowoc | Wisconsin | 54221 | — |
| Aurora Bay Area Medical Group-Marinette | Marinette | Wisconsin | 54143 | — |
| Bay Area Medical Center | Marinette | Wisconsin | 54143 | — |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | — |
| Marshfield Medical Center | Marshfield | Wisconsin | 54449 | — |
| Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Aurora Sinai Medical Center | Milwaukee | Wisconsin | 53233 | — |
| Marshfield Medical Center - Minocqua | Minocqua | Wisconsin | 54548 | — |
| ProHealth Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | 53066 | — |
| Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin | 54154 | — |
| Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh | Wisconsin | 54904 | — |
| Aurora Cancer Care-Racine | Racine | Wisconsin | 53406 | — |
| Aspirus Cancer Care - James Beck Cancer Center | Rhinelander | Wisconsin | 54501 | — |
| Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | 54868 | — |
| HSHS Saint Nicholas Hospital | Sheboygan | Wisconsin | 53081 | — |
| Vince Lombardi Cancer Clinic-Sheboygan | Sheboygan | Wisconsin | 53081 | — |
| Aspirus Cancer Care - Stevens Point | Stevens Point | Wisconsin | 54481 | — |
| Aurora Medical Center in Summit | Summit | Wisconsin | 53066 | — |
| Vince Lombardi Cancer Clinic-Two Rivers | Two Rivers | Wisconsin | 54241 | — |
| Aurora Cancer Care-Waukesha | Waukesha | Wisconsin | 53188 | — |
| ProHealth Waukesha Memorial Hospital | Waukesha | Wisconsin | 53188 | — |
| Aspirus Regional Cancer Center | Wausau | Wisconsin | 54401 | — |
| Aurora Cancer Care-Milwaukee West | Wauwatosa | Wisconsin | 53226 | — |
| Aurora West Allis Medical Center | West Allis | Wisconsin | 53227 | — |
| Marshfield Medical Center - Weston | Weston | Wisconsin | 54476 | — |
| Aspirus Cancer Care - Wisconsin Rapids | Wisconsin Rapids | Wisconsin | 54494 | — |
| Marshfield Clinic - Wisconsin Rapids Center | Wisconsin Rapids | Wisconsin | 54494 | — |
| Rocky Mountain Oncology | Casper | Wyoming | 82609 | — |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00601900, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 28, 2026 · Synced Oct 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00601900 live on ClinicalTrials.gov.