Safety and Efficacy Study of ADL5859 in Participants With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
Public ClinicalTrials.gov record NCT00603265. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group, Multicenter Study to Assess the Safety and Efficacy of ADL5859 100 mg BID in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the effectiveness of ADL5859 in relieving the pain associated with diabetic peripheral neuropathy (DPN) compared with placebo and duloxetine (a marketed drug approved for the treatment of painful DPN). The pain symptoms of DPN are thought to be due to damage to nerves caused by the diabetes.
Study identification
- NCT ID
- NCT00603265
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Industry
- Enrollment
- 226 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2007 (Type not available)
- Primary completion
- Aug 2008 (Actual)
- Completion
- Aug 2008 (Actual)
- Last update posted
- Jul 1, 2015
2007 – 2008
United States locations
- U.S. sites
- 27
- U.S. states
- 14
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Integrated Research Group | Riverside | California | 92506 | — |
| Torrance Clinical Research | Torrance | California | 90505 | — |
| FPA Clinical Research | Kissimmee | Florida | 34741 | — |
| Innovative Research of West Florida, Inc. | Largo | Florida | 33770 | — |
| Panhandle Family Care Associates & Emerald Coast Research Grp, Inc. | Marianna | Florida | 32446 | — |
| Renstar Medical Research | Ocala | Florida | 34471 | — |
| Radiant Research-St.Petersburg | Pinellas Park | Florida | 33781 | — |
| Doctor's Research Network | South Miami | Florida | 33143 | — |
| Metabolic Research Institute, Inc. | West Palm Beach | Florida | 33401 | — |
| Laszlo J. Mate, MD | West Palm Beach | Florida | 33407 | — |
| The Pain Treatment Center of the Bluegrass | Lexington | Kentucky | 40503 | — |
| Beacon Clinical Research | Brockton | Massachusetts | 02301 | — |
| Healthcare Research | Florissant | Missouri | 63031 | — |
| Creighton Diabetes Center, Creighton Univ. Sch. of Medicine | Omaha | Nebraska | 68131 | — |
| Advanced Biomedical Research of America | Las Vegas | Nevada | 89123 | — |
| Clnical Study Center of Asheville | Asheville | North Carolina | 28801 | — |
| Radiant Research-Akron | Mogadore | Ohio | 44260 | — |
| Neurology & Neuroscience Center of Ohio | Toledo | Ohio | 43623 | — |
| Aquilo Research | Yukon | Oklahoma | 73099 | — |
| Clinical Research Consultants, Research Department | Medford | Oregon | 97504 | — |
| Advanced Regional Center for Clinical Research (Ankle & Foot Care) | Altoona | Pennsylvania | 16602 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Nerve & Muscle Center of Texas | Houston | Texas | 77030 | — |
| Invisions Consultants LLC | San Antonio | Texas | 78217 | — |
| Diabetes & Glandular Disease Research Associates | San Antonio | Texas | 78229 | — |
| S.A.M. Clinical Research Center | San Antonio | Texas | 78229 | — |
| Tidewater Integrated Medical Research | Virginia Beach | Virginia | 23451 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00603265, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 1, 2015 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00603265 live on ClinicalTrials.gov.