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Completed Phase 3 Interventional

MOTION, Safinamide in Early IPD, as add-on to Dopamine Agonist

ClinicalTrials.gov ID: NCT00605683

Public ClinicalTrials.gov record NCT00605683. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 5, 2026, 7:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Double-blind, Placebo-controlled Randomised Trial to Determine the Efficacy and Safety of a Low (50 mg/Day) and High (100 mg/Day) Dose of Safinamide, as add-on Therapy, in Subjects With Early Idiopathic Parkinson's Disease Treated With a Stable Dose of a Single Dopamine Agonist

Study identification

NCT ID
NCT00605683
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Newron Pharmaceuticals SPA
Industry
Enrollment
679 participants

Conditions and interventions

Interventions

  • Safinamide (as add-on therapy) Drug

Drug

Eligibility (public fields only)

Age range
30 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2007
Primary completion
Dec 31, 2011
Completion
Feb 29, 2012
Last update posted
Oct 28, 2013

2007 – 2012

United States locations

U.S. sites
31
U.S. states
17
U.S. cities
30
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama
Arizona Neurological Institute Phoenix Arizona
Pacific Neuroscience Medical Group Oxnard California
San Francisco Clinical Research Center San Francisco California
Parkinson's Institute Sunnyvale California
Institute for Neurodegenerative Disorders New Haven Connecticut
Parkinson's Disease and Movement Disorder Center Boca Raton Florida
Neurologic Consultants P.A. Fort Lauderdale Florida
University Of Florida Gainesville Florida
Parkinson's Disease Treatment Center of SW Florida Port Charlotte Florida
Neurology Clinical Research Inc. Sunrise Florida
University Of South Florida Medical Center Tampa Florida
Emory University Atlanta Georgia
Medical College of Georgia Augusta Georgia
Columbus Research Institute Columbus Georgia
Northwestern University PD and Movement Disorders Center Chicago Illinois
University of Kansas Medical Center Kansas City Kansas
University of Maryland Medical Center Baltimore Maryland
Boston University School of Medicine Boston Massachusetts
Parkinson's Disease and Movement Disorders Center of Albany Albany New York
North Shore Medical Center Manhasset New York
Columbia University Medical Center New York New York
New York University New York New York
The Neurological Institute Charlotte North Carolina
Duke University Health Systems Druham North Carolina
Cleveland Clinic Cleveland Ohio
Neurology Specialists Dayton Ohio
Oregon Health & Science University Portland Oregon
Lankenau Hospital Wynnewood Pennsylvania
Butler Hospital Providence Rhode Island
Baylor College of Medicine Houston Texas

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 94 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00605683, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 28, 2013 · Synced May 5, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00605683 live on ClinicalTrials.gov.

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