Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study)
Public ClinicalTrials.gov record NCT00609180. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Prospective, Randomized, Multi-Center Trial of Initial Trophic Enteral Feeding Followed by Advancement to Full-Calorie Enteral Feeding vs. Early Advancement to Full-Calorie Enteral Feeding in Patients With Acute Lung Injury (ALI) or Acute Respiratory Distress Syndrome (ARDS) and Prospective, Randomized, Blinded, Placebo-Controlled, Multi-Center Trial of Omega-3 Fatty Acid, Gamma-Linolenic Acid, and Anti-Oxidant Supplementation in the Management of Acute Lung Injury (ALI) or Acute Respiratory Distress Syndrome (ARDS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are medical conditions that occur when there is severe inflammation and increased fluids in both lungs, making it difficult for the lungs to function properly. Hospital treatment for a person with ALI/ARDS often includes the use of a breathing machine, or ventilator, until the person is able to breathe without assistance. Initiating proper nutrition through a feeding tube early in a person's hospital stay may help to improve recovery, but the optimal timing, composition, and amount of feeding treatments are unknown. This study will evaluate whether early or delayed full-calorie feeding through a feeding tube is more effective in reducing recovery time and increasing survival rates in people with ALI/ARDS. The study will also determine whether supplementing the feedings with omega-3 fatty acids and antioxidants benefits people with ALI/ARDS.
Study identification
- NCT ID
- NCT00609180
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 272 participants
Conditions and interventions
Conditions
Interventions
- Minimal (Trophic) Feeding Behavioral
- Full Feeding Behavioral
- Omega-3 Fatty Acids and Antioxidant Supplements Dietary Supplement
- Placebo Dietary Supplement
Behavioral · Dietary Supplement
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2007 (Type not available)
- Primary completion
- Feb 2009 (Actual)
- Completion
- Apr 2009 (Actual)
- Last update posted
- Apr 13, 2016
2007 – 2009
United States locations
- U.S. sites
- 41
- U.S. states
- 14
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of San Francisco-Fresno Medical Center | Fresno | California | — | — |
| University of California, Davis Medical Center | Sacramento | California | — | — |
| UCSF-Moffitt Hospital | San Francisco | California | — | — |
| UCSF-San Francisco General Hospital | San Francisco | California | — | — |
| Centura St. Anthony Central Hospital | Denver | Colorado | — | — |
| Denver Health Medical Center | Denver | Colorado | — | — |
| Rose Medical Center | Denver | Colorado | — | — |
| University of Colorado Health Sciences Center | Denver | Colorado | — | — |
| Washington Hospital Center | Washington D.C. | District of Columbia | — | — |
| Baton Rouge General Hospital-Blue Bonnet | Baton Rouge | Louisiana | — | — |
| Baton Rouge General Hospital-Midcity | Baton Rouge | Louisiana | — | — |
| Earl K. Long Medical Center | Baton Rouge | Louisiana | — | — |
| Our Lady of the Lake Regional Medical Center | Baton Rouge | Louisiana | — | — |
| Medical Center of Louisiana | New Orleans | Louisiana | — | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | — | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | — | — |
| Baltimore VA Medical Center | Baltimore | Maryland | — | — |
| Johns Hopkins Bayview Medical Center | Baltimore | Maryland | — | — |
| Johns Hopkins Hospital | Baltimore | Maryland | — | — |
| University of Maryland Shock Trauma Center | Baltimore | Maryland | — | — |
| Baystate Medical Center | Springfield | Massachusetts | — | — |
| Rochester Methodist Hospital | Rochester | Minnesota | — | — |
| St. Mary's Hospital, Mayo Clinic | Rochester | Minnesota | — | — |
| University of North Carolina | Chapel Hill | North Carolina | — | — |
| Duke University Medical Center | Durham | North Carolina | — | — |
| Durham Regional Medical Center | Durham | North Carolina | — | — |
| Moses Cone Health System | Greensboro | North Carolina | — | — |
| Wesley Long Community Hospital | Greensboro | North Carolina | — | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | — | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | — | — |
| MetroHealth Medical Center | Cleveland | Ohio | — | — |
| University Hospitals of Cleveland | Cleveland | Ohio | — | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | — | — |
| Baylor College of Medicine | Houston | Texas | — | — |
| Intermountain Medical Center | Murray | Utah | — | — |
| McKay-Dee Hospital | Ogden | Utah | — | — |
| Utah Valley Regional Medical Center | Provo | Utah | — | — |
| LDS Hospital | Salt Lake City | Utah | — | — |
| University of Virginia Medical Center | Charlottesville | Virginia | — | — |
| Harborview Medical Center | Seattle | Washington | — | — |
| University of Washington | Seattle | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00609180, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2016 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00609180 live on ClinicalTrials.gov.