ClinicalTrials.gov record
Combination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer
ClinicalTrials.gov ID: NCT00613080
Public ClinicalTrials.gov record NCT00613080. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Evaluation of Preoperative Chemoradiotherapy Utilizing Intensity Modulated Radiation Therapy (IMRT) in Combination With Capecitabine and Oxaliplatin for Patients With Locally Advanced Rectal Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Giving these treatments before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving chemotherapy after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase II trial is studying the side effects and how well giving combination chemotherapy together with intensity-modulated radiation therapy works in treating patients undergoing surgery for locally advanced rectal cancer.
Study identification
- NCT ID
- NCT00613080
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 79 participants
Conditions and interventions
Conditions
Interventions
- capecitabine Drug
- oxaliplatin Drug
- resection Procedure
- radiation therapy Radiation
- FOLFOX Drug
Drug · Procedure · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2008 (Type not available)
- Primary completion
- Jan 2010 (Actual)
- Completion
- Dec 2016 (Actual)
- Last update posted
- Sep 25, 2018
2008 – 2016
United States locations
- U.S. sites
- 119
- U.S. states
- 28
- U.S. cities
- 97
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Providence Cancer Center at Providence Hospital | Mobile | Alabama | 36608 | — |
| Auburn Radiation Oncology | Auburn | California | 95603 | — |
| Radiation Oncology Centers - Cameron Park | Cameron Park | California | 95682 | — |
| Mercy Cancer Center at Mercy San Juan Medical Center | Carmichael | California | 95608 | — |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010-3000 | — |
| California Cancer Center - Woodward Park Office | Fresno | California | 93720 | — |
| Rebecca and John Moores UCSD Cancer Center | La Jolla | California | 92093-0658 | — |
| Radiation Oncology Center - Roseville | Roseville | California | 95661 | — |
| Radiological Associates of Sacramento Medical Group, Incorporated | Sacramento | California | 95815 | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| Veterans Affairs Medical Center - San Diego | San Diego | California | 92161 | — |
| Solano Radiation Oncology Center | Vacaville | California | 95687 | — |
| Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - Main Campus | Boca Raton | Florida | 33486 | — |
| University of Florida Shands Cancer Center | Gainesville | Florida | 32610-0232 | — |
| Baptist Cancer Institute - Jacksonville | Jacksonville | Florida | 32207 | — |
| Baptist-South Miami Regional Cancer Program | Miami | Florida | 33176 | — |
| Integrated Community Oncology Network - Orange Park | Orange Park | Florida | 32073 | — |
| Bay Medical | Panama City | Florida | 32401 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| John B. Amos Cancer Center | Columbus | Georgia | 31904 | — |
| Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center | Savannah | Georgia | 31403-3089 | — |
| Cancer Institute at St. John's Hospital | Springfield | Illinois | 62702 | — |
| Saint John's Cancer Center at Saint John's Medical Center | Anderson | Indiana | 46016 | — |
| Center for Cancer Care at Goshen General Hospital | Goshen | Indiana | 46526 | — |
| St. Vincent Oncology Center | Indianapolis | Indiana | 46260 | — |
| Cancer Center at Ball Memorial Hospital | Muncie | Indiana | 47303-3499 | — |
| Menorah Medical Center | Overland Park | Kansas | 66209 | — |
| Saint Luke's Hospital - South | Overland Park | Kansas | 66213 | — |
| Shawnee Mission Medical Center | Shawnee Mission | Kansas | 66204 | — |
| Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Dana-Farber/Brigham and Women's Cancer Center Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Boston University Cancer Research Center | Boston | Massachusetts | 02118 | — |
| Hudner Oncology Center at Saint Anne's Hospital - Fall River | Fall River | Massachusetts | 02721 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Mercy and Unity Cancer Center at Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Mercy and Unity Cancer Center at Unity Hospital | Fridley | Minnesota | 55432 | — |
| Minnesota Oncology Hematology, PA - Maplewood | Maplewood | Minnesota | 55109 | — |
| Virginia Piper Cancer Institute at Abbott - Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center | Robbinsdale | Minnesota | 55422-2900 | — |
| CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| Park Nicollet Cancer Center | Saint Louis Park | Minnesota | 55416 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| St. Francis Cancer Center at St. Francis Medical Center | Shakopee | Minnesota | 55379 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Minnesota Oncology Hematology, PA - Woodbury | Woodbury | Minnesota | 55125 | — |
| Regional Cancer Center at Singing River Hospital | Pascagoula | Mississippi | 39581 | — |
| Cancer Institute of Cape Girardeau, LLC | Cape Girardeau | Missouri | 63703 | — |
| Siteman Cancer Center at Barnes-Jewish St. Peters Hospital - St. Peters | City of Saint Peters | Missouri | 63376 | — |
| Truman Medical Center - Hospital Hill | Kansas City | Missouri | 64108 | — |
| Saint Luke's Cancer Institute at Saint Luke's Hospital | Kansas City | Missouri | 64111 | — |
| St. Joseph Medical Center | Kansas City | Missouri | 64114 | — |
| North Kansas City Hospital | Kansas City | Missouri | 64116 | — |
| Parvin Radiation Oncology | Kansas City | Missouri | 64116 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Saint Luke's East - Lee's Summit | Lee's Summit | Missouri | 64086 | — |
| Liberty Hospital | Liberty | Missouri | 64068 | — |
| Heartland Regional Medical Center | Saint Joseph | Missouri | 64506 | — |
| CCOP - Cancer Research for the Ozarks | Springfield | Missouri | 65802 | — |
| Hulston Cancer Center at Cox Medical Center South | Springfield | Missouri | 65807 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis | St Louis | Missouri | 63110 | — |
| Barnes-Jewish West County Hospital | St Louis | Missouri | 63141 | — |
| Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | — |
| CCOP - Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Renown Institute for Cancer at Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| Kingsbury Center for Cancer Care at Cheshire Medical Center | Keene | New Hampshire | 03431 | — |
| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756-0002 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740-6395 | — |
| Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton | Marlton | New Jersey | 08053 | — |
| J. Phillip Citta Regional Cancer Center at Community Medical Center | Toms River | New Jersey | 08755 | — |
| Maimonides Cancer Center at Maimonides Medical Center | Brooklyn | New York | 11219 | — |
| Monter Cancer Center of the North Shore-LIJ Health System | Lake Success | New York | 11042 | — |
| CCOP - North Shore University Hospital | Manhasset | New York | 11030 | — |
| Don Monti Comprehensive Cancer Center at North Shore University Hospital | Manhasset | New York | 11030 | — |
| Long Island Jewish Medical Center | New Hyde Park | New York | 11040 | — |
| Wayne Memorial Hospital, Incorporated | Goldsboro | North Carolina | 27534 | — |
| Wayne Radiation Oncology | Goldsboro | North Carolina | 27534 | — |
| Summa Center for Cancer Care at Akron City Hospital | Akron | Ohio | 44309-2090 | — |
| Barberton Citizens Hospital | Barberton | Ohio | 44203 | — |
| Charles M. Barrett Cancer Center at University Hospital | Cincinnati | Ohio | 45267 | — |
| Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center | Columbus | Ohio | 43210-1240 | — |
| Cancer Care Center, Incorporated | Salem | Ohio | 44460 | — |
| Precision Radiotherapy at University Pointe | West Chester | Ohio | 45069 | — |
| Cancer Treatment Center | Wooster | Ohio | 44691 | — |
| Oklahoma University Cancer Institute | Oklahoma City | Oklahoma | 73104 | — |
| Integris Oncology Services | Oklahoma City | Oklahoma | 73112 | — |
| Rosenfeld Cancer Center at Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19010 | — |
| Northeast Radiation Oncology Center | Dunmore | Pennsylvania | 18512 | — |
| Dale and Frances Hughes Cancer Center at Pocono Medical Center | East Stroudsburg | Pennsylvania | 18301 | — |
| Penn State Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Riddle Memorial Hospital Cancer Center | Media | Pennsylvania | 19063 | — |
| Upper Delaware Valley Cancer Center | Milford | Pennsylvania | 18337 | — |
| Cancer Center of Paoli Memorial Hospital | Paoli | Pennsylvania | 19301-1792 | — |
| Kimmel Cancer Center at Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107-5541 | — |
| Frankford Hospital Cancer Center - Torresdale Campus | Philadelphia | Pennsylvania | 19114 | — |
| CCOP - Main Line Health | Wynnewood | Pennsylvania | 19096 | — |
| Lankenau Cancer Center at Lankenau Hospital | Wynnewood | Pennsylvania | 19096 | — |
| Rhode Island Hospital Comprehensive Cancer Center | Providence | Rhode Island | 02903 | — |
| Hollings Cancer Center at Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center | Kingsport | Tennessee | 37662 | — |
| American Fork Hospital | American Fork | Utah | 84003 | — |
| Sandra L. Maxwell Cancer Center | Cedar City | Utah | 84720 | — |
| Jon and Karen Huntsman Cancer Center at Intermountain Medical Center | Murray | Utah | 84157 | — |
| Val and Ann Browning Cancer Center at McKay-Dee Hospital Center | Ogden | Utah | 84403 | — |
| Utah Valley Regional Medical Center - Provo | Provo | Utah | 84604 | — |
| LDS Hospital | Salt Lake City | Utah | 84103 | — |
| Utah Cancer Specialists at UCS Cancer Center | Salt Lake City | Utah | 84106 | — |
| Dixie Regional Medical Center - East Campus | St. George | Utah | 84770 | — |
| Norris Cotton Cancer Center - North | Saint Johnsbury | Vermont | 05819 | — |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | — |
| Southwest Virginia Regional Cancer Center at Wellmonth Health | Norton | Virginia | 24273 | — |
| Columbia Saint Mary's Hospital - Ozaukee | Mequon | Wisconsin | 53097 | — |
| Columbia-Saint Mary's Cancer Care Center | Milwaukee | Wisconsin | 53211 | — |
| Medical College of Wisconsin Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00613080, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 25, 2018 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00613080 live on ClinicalTrials.gov.