Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency
Public ClinicalTrials.gov record NCT00616811. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-center, Randomized, Double-blind, Active-controlled Clinical Trial to Evaluate the Safety and Tolerability of 24 Weeks Treatment With Vildagliptin (50 mg qd) Versus Sitagliptin (25 mg qd) in Patients With Type 2 Diabetes and Severe Renal Insufficiency
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This clinical trial is designed to provide additional information on the safety and tolerability of vildagliptin (50 mg once daily (qd)) and sitagliptin (25 mg qd) when used in patients with type 2 diabetes mellitus(T2DM) and severe renal insufficiency (Glomerular filtration rate (GFR) \< 30 mL/min) for a period of 24 weeks.
Study identification
- NCT ID
- NCT00616811
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 148 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2008 (Type not available)
- Primary completion
- Oct 2010 (Actual)
- Completion
- Oct 2010 (Actual)
- Last update posted
- Dec 17, 2020
2008 – 2010
United States locations
- U.S. sites
- 79
- U.S. states
- 32
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama Medical Center | Mobile | Alabama | — | — |
| Anasazi Internal Medicine | Phoenix | Arizona | — | — |
| University of Arkanasas for Medical Sciences | Little Rock | Arkansas | — | — |
| Office of William Zigrang | Burlingame | California | — | — |
| John Muir Clinical Research | Concord | California | — | — |
| Academic Medical Research Institute | Los Angeles | California | — | — |
| UCLA Medical Center | Los Angeles | California | — | — |
| Northern California Institute for Bone Health | Oakland | California | — | — |
| Dr. Wei Feng | Pasadena | California | — | — |
| Sierra Clinical Research - Orangevale | Roseville | California | — | — |
| Denver Nephrology PC | Denver | Colorado | — | — |
| Western Nephrology & Metabolic Bone Disease PC | Lakewood | Colorado | — | — |
| Western Nephrology & Metabolic Bone Disease PC | Westminster | Colorado | — | — |
| Hartford Hospital | Hartford | Connecticut | — | — |
| Nephrology Associates of South Miami | Aventura | Florida | — | — |
| University of Florida Shands Hospital | Gainesville | Florida | — | — |
| Center for Diabetes & Endocrine Care | Hollywood | Florida | — | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | — | — |
| Osler Medical Clinical Research | Melbourne | Florida | — | — |
| Tampa Bay Nephrology Associates | Tampa | Florida | — | — |
| Atlanta Diabetes Associates | Atlanta | Georgia | — | — |
| Emory Clinic | Atlanta | Georgia | — | — |
| University of Hawaii | Honolulu | Hawaii | — | — |
| Boise Kidney & Hypertension Institiute | Meridian | Idaho | — | — |
| Iowa Diabetes & Endocrinology Research Center PLC | Des Moines | Iowa | — | — |
| University of Iowa | Iowa City | Iowa | — | — |
| Cray Diabetes Education Center | Kansas City | Kansas | — | — |
| Cotton-O'Neil Diabetes & Endocrinology Center | Topeka | Kansas | — | — |
| Dolby Research, LLC | Baton Rouge | Louisiana | — | — |
| Metabolic Center of Louisiana | Baton Rouge | Louisiana | — | — |
| Bruce Samuels LLC | Covington | Louisiana | — | — |
| Crescent City Clinical Research Center | Metairie | Louisiana | — | — |
| Egan Healthcare | Metairie | Louisiana | — | — |
| Arthritis and Diabetes Clinic | Monroe | Louisiana | — | — |
| Northwest Louisiana Nephrology Research | Shreveport | Louisiana | — | — |
| Joslin Diabetes Center at North Arundel Hospital | Glen Burnie | Maryland | — | — |
| Biolab Research, LLC | Rockville | Maryland | — | — |
| Genesys Integrated Group Practice, PC | Flint | Michigan | — | — |
| Phillips Medical Services, PLLC | Jackson | Mississippi | — | — |
| Mississippi Medical Research, LLC | Picayune | Mississippi | — | — |
| Diabetes and Endocrinology Specialist, Inc | Chesterfield | Missouri | — | — |
| Jefferson City Medical Group | Jefferson City | Missouri | — | — |
| Arms, Dodge, Robinson, Wilber & Crouch, Inc. | Kansas City | Missouri | — | — |
| Washington U School of Medicine | St Louis | Missouri | — | — |
| Platte Valley Medical Group | Kearney | Nebraska | — | — |
| Creighton Diabetes Center | Omaha | Nebraska | — | — |
| Creighton Nephrology | Omaha | Nebraska | — | — |
| UMDNJ-Robert Wood Johnson | New Brunswick | New Jersey | — | — |
| University of New Mexico Health Science Center | Albuquerque | New Mexico | — | — |
| Downstate University of Brooklyn | Brooklyn | New York | — | — |
| HRRG | Orchard Park | New York | — | — |
| Mayo Clinic Rochester | Rochester | New York | — | — |
| SUNY - Upstate Medical University | Syracuse | New York | — | — |
| Meritcare Medical Group | Fargo | North Dakota | — | — |
| Hightop Medical Research Center | Cincinnati | Ohio | — | — |
| University of Cincinnati | Cincinnati | Ohio | — | — |
| The Ohio State University Medical Center | Columbus | Ohio | — | — |
| Willamette Valley Clinical Studies | Eugene | Oregon | — | — |
| Lehigh Valley Hospital-Dept. of Medicine Research | Allentown | Pennsylvania | — | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | — | — |
| Renal Endocrine Associates, P. C. | Pittsburgh | Pennsylvania | — | — |
| Aiken Center for Clinical Research | Aiken | South Carolina | — | — |
| Medical U of South Carolina | Charleston | South Carolina | — | — |
| SC Nephrology and Hyptertension Center, Inc. | Orangeburg | South Carolina | — | — |
| Sumter Medical Specialists | Sumter | South Carolina | — | — |
| AM Diabetes and Endocrinology Center | Bartlett | Tennessee | — | — |
| Medical Nephrology Associates | Dyersburg | Tennessee | — | — |
| Dallas Diabetes & Endocrine Center | Dallas | Texas | — | — |
| North Texas Endocrine Center | Dallas | Texas | — | — |
| Texas Tech University Health Sciences | El Paso | Texas | — | — |
| Baylor Clinic (BCM 621) | Houston | Texas | — | — |
| Baylor College of Medicine | Houston | Texas | — | — |
| Allied Institute of Medicine | San Antonio | Texas | — | — |
| Central Utah Clinic | American Fork | Utah | — | — |
| Clinical Research and Consulting Center, LLC | Fairfax | Virginia | — | — |
| Medical College of Virginia | Richmond | Virginia | 23298 | — |
| Medical College of Virginia | Richmond | Virginia | — | — |
| Washington State University at Spokane | Spokane | Washington | — | — |
| UW Health - West | Madison | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00616811, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 17, 2020 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00616811 live on ClinicalTrials.gov.